Zobrazeno 1 - 8
of 8
pro vyhledávání: '"V. I. Uzgiris"'
Publikováno v:
Biochemistry. 16:593-600
Absorbance changes in the spectrum of cytochrome P-450 were related to the inhibition of [26-14C]cholesterol oxidation to [14C]isocaproate and pregnenolone in mitochondria from bovine corpus luteum produced by two types of ligands. Nitrogenous inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734c5eede5d2650020ced4bfcbccb090
https://doi.org/10.1021/bi00623a006
https://doi.org/10.1021/bi00623a006
Autor:
V. I. Uzgiris, Kiyoko Kashiwagi, Hilton A. Salhanick, P. E. Graves, M. Querner, E. N. McIntosh
Publikováno v:
Endocrinology. 102:1077-1087
The inhibitory activity of cyanoketone (CNK; 2alpha-cyano-4,4,17alpha-trimethyl-17beta-hydroxy-5-androsten-3-one), was investigated for enzymes of the respiratory chain and cholesterol side chain cleavage (CSCC). In bovine corpus luteum mitochondria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d9bac9d2149be0360c4c82d11c8eb9
https://doi.org/10.1210/endo-102-4-1077
https://doi.org/10.1210/endo-102-4-1077
Publikováno v:
Biochemistry. 10:2916-2923
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c328145389e17f9c9f641b56fe04c3c4
https://doi.org/10.1021/bi00791a019
https://doi.org/10.1021/bi00791a019
Publikováno v:
Biochemistry. 10:2909-2916
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8461c52e8246e992897ab031c5f2aed
https://doi.org/10.1021/bi00791a018
https://doi.org/10.1021/bi00791a018
Publikováno v:
Advances in experimental medicine and biology. 58(00)
The implications of ligand modified spectra of cytochrome P-450 in mitochondria from corpus luteum are considered. Mitochondria from bovine corpus luteum contain a single cytochrome P-450 which oxidizes cholesterol to pregnenolone and isocaproaldehyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::179dc956a12aa5585ae85d03ad98ce66
https://pubmed.ncbi.nlm.nih.gov/1155251
https://pubmed.ncbi.nlm.nih.gov/1155251
Publikováno v:
Endocrinology. 101(1)
Because aminoglutethimide is a potentially important drug in the treatment of certain maligancies as well as fertility control, its stereoisomers were studied for binding to corpus luteum mitochondrial cytochrome P-450 and inhibition of cholesterol s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be6ed2c7096523898ed53b0fed80e31a
https://pubmed.ncbi.nlm.nih.gov/862564
https://pubmed.ncbi.nlm.nih.gov/862564
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461590286
It is now well established that many reagents can modify the cytochrome P-450 spectrum. These modifications are produced. by the interaction of ligands with hemoprotein or the iron of the heme prosthetic group (13). The modified cytochrome P-450 diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d47249ce61fe4c28f0557778d070224
https://doi.org/10.1007/978-1-4615-9026-2_15
https://doi.org/10.1007/978-1-4615-9026-2_15
Publikováno v:
Endocrinology. 86(3)
Studies using intact bovine adrenocortical mitochondria reveal that clofibrate (chlorophenoxyisobutyrate, CPIB), a hypolipidemic drug, blocks steroid 11β-hydroxylation supported by malate or succinate without affecting the function of the mitochondr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359d7edbf5c5b6fec1d9197376dd5870
https://pubmed.ncbi.nlm.nih.gov/4391389
https://pubmed.ncbi.nlm.nih.gov/4391389