Zobrazeno 1 - 10 of 17 pro vyhledávání: '"V. I. Shmurak"'
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Akademický článek
Physicochemical and Functional Characterization of Medicinal Product Rinsulin® R
Autor: A. V. Babina, R. V. Drai, V. B. Saparova, A. N. Afanasyeva, P. G. Zaikin, V. I. Shmurak, T. E. Eltysheva, I. E. Makarenko
Publikováno v: Разработка и регистрация лекарственных средств, Vol 12, Iss 2, Pp 124-134 (2023)
Introduction. Currently, biosimilars have found quite widespread use in the treatment of a number of chronic and life-threatening diseases. Thanks to them, there is a significant decrease of the economic pressure of biological drugs on the health car
Externí odkaz: https://doaj.org/article/786a8dd4fc784d75aae394661378ffa3
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3
Serum albumin in health and disease: esterase, antioxidant, transporting and signaling properties
Autor: Richard O. Jenkins, Daria A. Belinskaia, Polina A Voronina, V. I. Shmurak, Nikolay V. Goncharov
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10318, p 10318 (2021)
The Publisher's final version can be found by following the DOI link. Open access article. Being one of the main proteins in the human body and many animal species, albumin plays a decisive role in the transport of various ions—electrically neutral
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2568ee265812a6ce7fe0565cd0af3a0
https://doi.org/10.3390/ijms221910318
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4
The Rat (Rattus norvegicus) as a Model Object for Acute Organophosphate Poisoning. 2. A System Analysis of the Efficacy of Green Tea Extract in Preventing Delayed Effects of Poisoning
Autor: V. I. Shmurak, M. K. Serebryakova, Pavel V. Avdonin, E. A. Korf, Daria A. Belinskaia, Maxim A. Terpilowski, V. E. Sobolev, Igor Kudryavtsev, Nikolay V. Goncharov
Publikováno v: Journal of Evolutionary Biochemistry and Physiology. 55:208-221
Studying the drugs of natural origin that promote recovery of an organism after acute poisoning with household and industrial toxicants, including organophosphates (OPs), is a challenge not only to toxicology but also informatics, which is a major to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::915d5756003f012d96a482e66330810c
https://doi.org/10.1134/s0022093019030062
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6
The Universal Soldier: Enzymatic and Non-Enzymatic Antioxidant Functions of Serum Albumin
Autor: Richard O. Jenkins, Nikolay V. Goncharov, Mikhail A. Vovk, V. I. Shmurak, Daria A. Belinskaia, Polina A Voronina, A. A. Batalova
Publikováno v: Antioxidants, Vol 9, Iss 966, p 966 (2020)
Antioxidants
open access article As a carrier of many biologically active compounds, blood is exposed to oxidants to a greater extent than the intracellular environment. Serum albumin plays a key role in antioxidant defence under both normal and oxidative stress
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38eb5b1a0d0f32d531679337b7b7546
https://www.mdpi.com/2076-3921/9/10/966
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7
Experimental modeling for delayed effects of organophosphates
Autor: Ekaterina Korf, V. I. Shmurak, Pavel V. Avdonin, Daria A. Belinskaia, Richard O. Jenkins, Nikolay V. Goncharov
The remote effects of acute poisoning with organophosphates (OPs) are poorly studied, and the experimental models used often disregard species-related traits. Here we compare two toxicological models, both with rats as the model animal and paraoxon (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130e904772948bf5e898acb545a0a3a4
https://doi.org/10.1016/b978-0-12-819090-6.00050-7
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8
Esterase Activity of Serum Albumin Studied by 1H NMR Spectroscopy and Molecular Modelling
Autor: Mikhail A. Vovk, Richard O. Jenkins, V. I. Shmurak, Daria A. Belinskaia, A. A. Batalova, Nikolay V. Goncharov, Polina A Voronina
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 10593, p 10593 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 19
The Publisher's final version can be found by following the DOI link. Open access article. Serum albumin possesses esterase and pseudo-esterase activities towards a number of endogenous and exogenous substrates, but the mechanism of interaction of va
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdff3ad355673f1785c0a17810fb643
https://doi.org/10.3390/ijms221910593
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9
Comparative analysis of esterase and paraoxonase activities of different serum albumin species
Autor: Nikolay V. Goncharov, M. A. Terpilovskii, Pavel V. Avdonin, V. I. Shmurak, D. A. Belinskaya
Publikováno v: Journal of Evolutionary Biochemistry and Physiology. 53:271-281
Enzymatic activities of three types of serum albumin—rat, bovine and human—were analyzed comparatively using a mathematical model. Kinetic and equilibrium constants of carboxylesterase and paraoxonase activities of albumin in Sudlow’s sites I a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a991b203efdf78e7d5fffcd8c442ce4
https://doi.org/10.1134/s0022093017040032
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10
In silico analysis of paraoxon binding by human and bovine serum albumin
Autor: P. P. Avdonin, K. I. Taborskaya, D. A. Belinskaya, V. I. Shmurak, Pavel V. Avdonin, Nikolay V. Goncharov
Publikováno v: Journal of Evolutionary Biochemistry and Physiology. 53:191-199
Albumin is known to be able to cleave ether bonds in organophosphates (OPs). Amino acids responsible for esterase and pseudo-esterase albumin activity towards OPs are not yet finally identified. Presumably, Sudlow’s site I with the Tyr150 residue s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49d4ba6e4385196cc983fd53fd017eac
https://doi.org/10.1134/s0022093017030036
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