Zobrazeno 1 - 10
of 81
pro vyhledávání: '"V. I. Mitashov"'
Publikováno v:
Biology Bulletin. 35:355-361
Molecular-genetic mechanisms of regeneration of adult newt (Pleurodeles waltl) retina were studied. For the first time, a comparative analysis of the expression of regulatory genes Pax6, Otx2, and Six3 and Fgf2 genes encoding signal molecules was per
Autor:
R. D. Zinovieva, Gennady T. Sukhikh, Yu. A. Smirnova, I. G. Panova, V. I. Mitashov, Yu. V. Markitantova, N. V. Firsova, O. V. Podgornyi
Publikováno v:
Biology Bulletin. 35:121-125
The expression of β-III tubulin, a marker protein of early neuronal cells, was studied by molecular genetic and immunochemical techniques. The study was performed with the eyes of human fetuses on weeks 8.5 to 27–28 of intrauterine development. Ex
Autor:
Gennady T. Sukhikh, R. D. Zinovieva, N. V. Firsova, I. G. Panova, Yu. V. Markitantova, V. I. Mitashov, Yu. A. Smirnova
Publikováno v:
Biology Bulletin. 35:113-120
The pattern of the PITX2 gene expression was studied in the cornea, lens, retina, iridocorneal complex (ICC), and eye coats of human fetuses at weeks 9.5–22 of intrauterine development. Using the PCR method, PITX2 expression in all these tissues wa
Autor:
I. G. Panova, Yu. V. Markitantova, R. D. Zinovieva, V. I. Mitashov, Yu. A. Smirnova, Gennady T. Sukhikh, N. V. Firsova
Publikováno v:
Biology Bulletin. 35:108-112
This study is part of the project aimed at identification and structural-functional analysis of the regulatory genes specific for multipotent embryonic stem cells (ESCs). For the first time, primers constructed on the basis of OCT4 and NANOG mRNAs we
Autor:
V. I. Mitashov
Publikováno v:
Russian Journal of Developmental Biology. 38:198-205
Comparative analysis of the early transformations of differentiated cells of the pigment epithelium, ciliary fold epithelium, and Muller glia in the eye of lower vertebrates and mammals during retina regeneration and cultivation was performed for the
Autor:
Yu. A. Smirnova, R. D. Zinov’eva, I. G. Panova, Gennady T. Sukhikh, V. I. Mitashov, Yu. V. Markitantova
Publikováno v:
Biology Bulletin. 33:339-346
Expression of transcription factors PAX6, PROX1, and PITX2 was evaluated in eye tissues after 9.5 and 22.0 weeks of human fetus development using polymerase chain reaction. Pax6, Prox1 and Pitx2 expression has been revealed in the cornea, lens, retin
Autor:
V. I. Mitashov, S. G. Vassetzky
Publikováno v:
Russian Journal of Developmental Biology. 37:123-126
Publikováno v:
Advances in Space Research. 38:1071-1078
The model of Wolffian lens regeneration was used to study the effect of microgravity on the proliferative activity of cell giving rise to the regenerating lens. In vivo experiments were performed aboard Russian biosatellites and under laboratory cond
Autor:
V. I. Mitashov
Publikováno v:
Russian Journal of Developmental Biology. 36:240-246
Studies have been considered, which concern identification of regulatory genes in adult newts and their expression during retinal and lens regeneration. B.L. Astaurov repeatedly urged to join efforts of geneticists and embryologists in studies of the
Publikováno v:
Biology Bulletin. 31:428-436
We studied tissue-specific expression of homeobox genes Pax6, Prox1, and Six3 during regeneration of the retina and lens. In the native retina, mRNA of Pax6, Prox1, and Six3 was predominantly localized in ganglion cells and in the inner nuclear layer