Zobrazeno 1 - 10
of 26
pro vyhledávání: '"V. I. Kazey"'
Autor:
A. L. Khokhlov, D. Yu. Grebenkin, E. K. Faeva, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 12, Iss 1, Pp 142-153 (2023)
Introduction. As a part of the registration of the drug product a bioequivalence study of the fixed-dose combination "Ezetimibe + rosuvastatin" (JSC "Sanofi-aventis group", Russia) compared with coadministered Ezetrol® (ezetimibe) and Crestor® (ros
Externí odkaz:
https://doaj.org/article/0772376aaac44f4fa872234488c64c39
Autor:
S. B. Fitilev, Yu. F. Glukhov, S. V. Lukyanov, V. I. Kazey, I. B. Bondareva, A. V. Vozzhaev, I. I. Shkrebniova, D. A. Kliuev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 3, Pp 10-19 (2022)
Relevance. As part of the conducted open non-randomized phase I clinical trial the pharmacokinetics (PK) of the first Russian novel antiplatelet agent Angipur (nonpeptide glycoprotein IIb/IIIa receptor inhibitor) was studied.Aim of the research was t
Externí odkaz:
https://doaj.org/article/bbfa144af3a940a6a9dd174d364c51a6
Autor:
A. L. Khokhlov, D. Yu. Grebenkin, E. K. Faeva, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 61-74 (2022)
Introduction. The advantages of fixed-dose combination losartan + amlodipine + rosuvastatin compared to mono-drugs and two-component combinations are to increase the therapeutic efficacy, to reduce the cost of the product and to make the drug easier
Externí odkaz:
https://doaj.org/article/0c36285512054bd1a052f528905cda52
Autor:
I. G. Gordeev, V. I. Kazey, A. V. Kapashin, E. Е. Luchinkina, A. A. Globenko, А. L. Vladykin, E. A. Jain, A. I. Cherenkova, I. A. Kokorin, N. N. Levchuk, Т. V. Smolina, Р. D. Sobolev, S. Yu. Gorbacheva
Publikováno v:
Антибиотики и Химиотерапия, Vol 66, Iss 1-2, Pp 19-25 (2021)
Relevance. Pentanedioic acid imidazolyl ethanamide (PAIE) has been used clinically as an antiviral agent for a long time, however, there is no information in the available literature concerning the dependence of PAIE pharmacokinetics on isoenzymes po
Externí odkaz:
https://doaj.org/article/80543123a18547c9a7e048ffd9e3a8d7
Autor:
S. B. Fitilev, Yu. F. Glukhov, S. V. Lukyanov, A. V. Vozzhaev, I. I. Shkrebniova, V. I. Kazey, I. B. Bondareva
Publikováno v:
Кардиоваскулярная терапия и профилактика, Vol 21, Iss 3 (2022)
Aim. To study the tolerability, safety, pharmacokinetics (PK) and pharmacodynamics of single intravenous infusions of Angipur in healthy male volunteers.Material and methods. The Phase I trial included 20 healthy male volunteers (mean age, 30,8±7,7
Externí odkaz:
https://doaj.org/article/57e93bdde320438eaa2e3187eda7f1ee
Autor:
V. Kubesh, A. L. Khokhlov, A. M. Shitova, Yu. A. Dzhurko, V. I. Kazey, A. A. Khokhlov, A. E. Miroshnikov, O. V. Lebedeva, I. K. Klaus, A. V. Zyatenkov
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 9, Iss 4, Pp 155-163 (2020)
Introduction. A fixed dose combination of telmisartan and amlodipine is widely used in clinical practice during hypertension treatment. Combination of telmisartan and amlodipine demonstrates potentiating synergistic effect on blood pressure decrease.
Externí odkaz:
https://doaj.org/article/8bfbbc454e4d40dba257927d6c21b606
Publikováno v:
Рациональная фармакотерапия в кардиологии, Vol 16, Iss 3, Pp 348-355 (2020)
Aim. To compare the kinetics of dissolution (in vitro) and some pharmacodynamic and pharmacokinetic parameters of branded generic preparations of acetylsalicylic acid (ASA) in buffered form in cardioprotective doses [ASA 75 mg+Mg(OH)2 15.2 mg], which
Externí odkaz:
https://doaj.org/article/13a11a623597417da5b4b49edfd8e8c6
Autor:
N. V. Eremina, V. I. Kazey, O. Y. Kravtsova, E. I. Skrabelinskaya, A. V. Purmal, A. D. Durnev
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 1, Pp 38-43 (2020)
An experimental drug CBL0100 is developed as an antifungal agent for topical application. In order to assess the effect of composition of the formulation on transdermal absorption, a comparative absorption study of its pharmacokinetics and biodistrib
Externí odkaz:
https://doaj.org/article/6c9aa5c06f764d4b948c85029caf8807
Autor:
N. B. Abramenko, P. I. Vnukova, E. S. Golovina, I. E. Makarenko, A. A. Mosikian, A. G. Nikiforova, P. V. Gremyakova, V. I. Kazey
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 8, Iss 3, Pp 70-78 (2019)
Introduction. IImmunogenicity identification of therapeutic proteins, such as human insulin analogues, is one of the most relevant and significant area in medicine and pharmaceuticals. Determination the possibility of producing neutralizing antibodie
Externí odkaz:
https://doaj.org/article/9e0df99d461c4dada32752a690fe9619
Autor:
E. A. Kashukh, E. A. Poluektova, A. V. Kudryavtseva, G. S. Krasnov, V. I. Kazey, P. D. Sobolev, P. V. Gremyakova, V. T. Ivashkin
Publikováno v:
Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 29, Iss 4, Pp 38-49 (2019)
Aim. To assess the effect of rifaximin and a multi-strain probiotic on the intestinal microbiome and the indicators of cardiovascular risk in patients with coronary heart disease (CHD).Materials and methods. A study conducted during the 2016–2019 p
Externí odkaz:
https://doaj.org/article/6fe27df85c254bf0acf5d7e109c167fb