Zobrazeno 1 - 8 of 8 pro vyhledávání: '"V. I. Bakhtina"'
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Akademický článek
Comparison of fragment analysis and PCR electrophoresis methods for the detection of FLT3‑ITD mutations in patients with acute myeloid leukemia
Autor: I. E. Maslyukova, D. V. Kurochkin, E. V. Martynova, V. I. Bakhtina, T. N. Subbotina
Publikováno v: Онкогематология, Vol 17, Iss 4, Pp 118-125 (2022)
Background. The presence of the FLT3-ITD mutations in patients with AML serves as a marker of poor prognosis, which is included in the ELN 2017 risk stratification guideline. The main criterion for dividing patients into groups according to the predi
Externí odkaz: https://doaj.org/article/949671ee51664c06bc72c94200295a60
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2
Study of the Janus kinase 2 (JAK2) gene haplotype 46/1 association with driver mutations of chronic Ph-negative myeloproliferative neoplasms
Autor: I. А. Olkhovskiy, M. A. Stolyar, Yu. Yu. Komarovskiy, A. S. Gorbenko, V. I. Korchagin, E. A. Dunaeva, K. O. Mironov, V. I. Bakhtina, T. I. Olkhovik, E. V. Vasiliev, M. A. Mikhalev
Publikováno v: Russian journal of hematology and transfusiology. 67:377-387
Introduction. Haplotype JAK2 46/1 is associated with more frequent development of Ph-negative myeloproliferative neoplasms (MPN) and with an increased detection rate of the JAK2 V617F mutation. At the same time, the molecular mechanisms of such assoc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f77c73190051f30e010f0b9a114adb70
https://doi.org/10.35754/0234-5730-2022-67-3-377-387
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3
Use of the «BCR/ABL – multitest» kit in the algorithm of laboratory diagnostics of oncohematological diseases: economic aspects
Autor: M. A. Mikhalev, T I Olkhovik, M.A. Stolyar, E E Mochalova, K E Orlova, V I Bakhtina, E. V. Vasiliev, A. S. Gorbenko, I. A. Olkhovskiy
Publikováno v: Russian Clinical Laboratory Diagnostics. 66:571-576
Abnormal mRNAs of the hybrid BCR-ABL gene in the majority of cases initiate the synthesis of proteins with a mass of 210 kDa (p210), 190 kDa (p190), and 230 kDa (p230). Expression of the p210 variant is most common in CML (95% of cases), while the p1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31fe46c67a3bf4fe8e4d01241ef4598
https://doi.org/10.51620/0869-2084-2021-66-9-571-576
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4
Study of mRNA of WT1, BAALC, EVI1, PRAME and HMGA2 genes in whole blood samples
Autor: I. A. Olkhovskiy, A. S. Gorbenko, M. A. Stolyar, V. I. Bakhtina, M. A. Mikhalev, T. I. Olkhovik, A. B. Sudarikov, Yu. S. Sidorova, T. I. Pospelova, M. A. Kolesnikova, T. S. Kaporskaya, V. A. Lyskova
Publikováno v: Klinicheskaia laboratornaia diagnostika. 67(10)
Simultaneous quantitative measurement of mRNA of the WT1, BAALC, EVI1, PRAME and HMGA2 genes in whole blood samples reflects the specific pathological proliferative activity in acute leukemia and their ratio is promising as a diagnostic marker. The t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35592bbed34e51bc200e4c2624dd27ec
https://pubmed.ncbi.nlm.nih.gov/36315178
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5
Development of a method for the determination of the JAK2 gene mRNA in venous blood and assessment of its diagnostic value in oncohematology
Autor: M A, Stolyar, A S, Gorbenko, I A, Olkhovskiy, V I, Bakhtina, M A, Mikhalev, T I, Olkhovik, Yu Yu, Komarovskiy
Publikováno v: Klinicheskaia laboratornaia diagnostika. 66(6)
Overactive JAK pathway signaling is a hallmark of immune diseases and critically affects on inflammation and coagulation. A number of mutations in the JAK2 gene act as driving forces of myeloproliferative neoplasms (MPN), the pathogenesis of certain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1ee116d7a4f00a270c6fd5d81fa7667f
https://pubmed.ncbi.nlm.nih.gov/34105916
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6
A comparative protein profiling of lymphocytes from blood of patients with chronic lymphoid leukemia by high-resolution mass-spectrometry in search of new markers for heterogeneity and disease prognosis
Autor: M. A. Komarova, Anna S. Zamay, Yu. E. Glazyrin, V. I. Bakhtina, T. N. Zamay, Irina Demko, M. V. Silacheva
Publikováno v: Journal of Analytical Chemistry. 71:1242-1250
To find new markers of chronic lymphoid leukemia heterogeneity, a comparison of the proteomic profiles of pathologic and healthy lymphocytes from blood was carried out by high-resolution mass spectrometry and label-free quantitative analysis. A list
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5b1ca0b8a5bd8d742bac7fba22ac6cb
https://doi.org/10.1134/s1061934816130062
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