Zobrazeno 1 - 10
of 401
pro vyhledávání: '"V. Hingorani"'
Autor:
Dina V. Hingorani, Michael M. Allevato, Maria F. Camargo, Jacqueline Lesperance, Maryam A. Quraishi, Joseph Aguilera, Ida Franiak-Pietryga, Daniel J. Scanderbeg, Zhiyong Wang, Alfredo A. Molinolo, Diego Alvarado, Andrew B. Sharabi, Jack D. Bui, Ezra E. W. Cohen, Stephen R. Adams, J. Silvio Gutkind, Sunil J. Advani
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Monomethyl auristatin (MMAE), also known for its radiosensitizer properties, is a common antibody drug conjugate used for cancer therapy. Here the authors show that, in combination with radiotherapy, tumor-directed antibodies or peptides conjugated t
Externí odkaz:
https://doaj.org/article/72a567e57f8f44099d033840d2c36067
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
MMAF anti-HER2 antibody conjugates increase tumor G2/M fraction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1723b32cf892f5d409c14d9790a7e0db
https://doi.org/10.1158/1535-7163.22510615
https://doi.org/10.1158/1535-7163.22510615
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Antibody conjugation to drug and Cy5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a179658065a55345f7cf28265177a8b
https://doi.org/10.1158/1535-7163.22510627.v1
https://doi.org/10.1158/1535-7163.22510627.v1
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
MMAF anti-HER2 antibody conjugates spatial localization in HER2 negative tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae83cc61940585a81d6fb8e38d575c3
https://doi.org/10.1158/1535-7163.22510618
https://doi.org/10.1158/1535-7163.22510618
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Effect of auristatin antibody drug conjugates in combination with IR on mouse body weight.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18bb299fd6b025e9e09dc22f7a1e311e
https://doi.org/10.1158/1535-7163.22510609
https://doi.org/10.1158/1535-7163.22510609
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Statistical analysis of xenograft studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a1fd44762e98c536c352fc441be0ea
https://doi.org/10.1158/1535-7163.22510606
https://doi.org/10.1158/1535-7163.22510606
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
The most successful therapeutic strategies for locally advanced cancers continue to combine decades-old classical radiosensitizing chemotherapies with radiotherapy. Molecular targeted radiosensitizers offer the potential to improve the therapeutic ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd3f628464365f0f590a2f3623f5545
https://doi.org/10.1158/1535-7163.c.6539665.v1
https://doi.org/10.1158/1535-7163.c.6539665.v1
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Pertuzumab conjugated MMAE and IR tumor control.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad88318303c9787d3c2aff057aa22641
https://doi.org/10.1158/1535-7163.22510612.v1
https://doi.org/10.1158/1535-7163.22510612.v1
Autor:
Sunil J. Advani, Stephen R. Adams, Andrew M. Lowy, Ezra E.W. Cohen, Daniel J. Scanderbeg, Donald Pizzo, Seung M. Song, Joseph Aguilera, Maria F. Camargo, Matthew K. Doan, Dina V. Hingorani
Cell line HER2 expression and Anti-HER2 antibody drug conjugate binding.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29580e87e25ce1d3c47546e903b31bb3
https://doi.org/10.1158/1535-7163.22510624.v1
https://doi.org/10.1158/1535-7163.22510624.v1
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 365 (2021)
Recent advances in immunotherapy have revolutionized cancer therapy. Immunotherapies can engage the adaptive and innate arms of the immune system. Therapeutics targeting immune checkpoint inhibitors (i.e., CTLA-4; PD-1, and PD-L1) have shown efficacy
Externí odkaz:
https://doaj.org/article/e0910e6f97284d0b8db6239b45e3a1b6