Zobrazeno 1 - 10
of 576
pro vyhledávání: '"V. Harding"'
Autor:
K. Blighe, L. DeDionisio, K. A. Christie, B. Chawes, S. Shareef, T. Kakouli-Duarte, C. Chao-Shern, V. Harding, R. S. Kelly, L. Castellano, J. Stebbing, J. A. Lasky-Su, M. A. Nesbit, C. B. T. Moore
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-20 (2018)
Abstract The reporting of the first draft of the human genome in 2000 brought with it much hope for the future in what was felt as a paradigm shift toward improved health outcomes. Indeed, we have now mapped the majority of variation across human pop
Externí odkaz:
https://doaj.org/article/4feeada48a6a48378ba59474cc3eadf1
Autor:
Samuel Kraus, Megan L Fletcher, Urszula Łapińska, Krina Chawla, Evan Baker, Erin L Attrill, Paul O'Neill, Audrey Farbos, Aaron Jeffries, Edouard E Galyov, Sunee Korbsrisate, Kay B Barnes, Sarah V Harding, Krasimira Tsaneva-Atanasova, Mark A T Blaskovich, Stefano Pagliara
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012361 (2024)
The interactions between a virus and its host vary in space and time and are affected by the presence of molecules that alter the physiology of either the host or the virus. Determining the molecular mechanisms at the basis of these interactions is p
Externí odkaz:
https://doaj.org/article/b6c3583e1ed849f4a0d265bd93bc466b
Autor:
Jason R. Bush, Jun Han, Edward C. Deehan, Scott V. Harding, Madhura Maiya, Joshua Baisley, David Schibli, David R. Goodlett
Publikováno v:
Journal of Functional Foods, Vol 108, Iss , Pp 105740- (2023)
Histamine from our diet or gut microbes can trigger gastrointestinal disturbances, and resistant potato starch (RPS) has previously been shown to alleviate these symptoms while increasing levels of health-associated bacteria such as Akkermansia throu
Externí odkaz:
https://doaj.org/article/f3f8813ef36b4637b228547a9c9501a1
Autor:
Tetsuya Yoshimoto, Mizuho Kittaka, Andrew Anh Phuong Doan, Rina Urata, Matthew Prideaux, Roxana E. Rojas, Clifford V. Harding, W. Henry Boom, Lynda F. Bonewald, Edward M. Greenfield, Yasuyoshi Ueki
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
MYD88 mediates the signal of bacterial infection. Here, in the context of periodontal infection, the authors show that the MYD88 pathway in osteocytes plays a dominant role in regulating osteolysis.
Externí odkaz:
https://doaj.org/article/e16f005c0ee94c278ec83641515e371c
Autor:
Adam Pattinson, Sandeep Bahia, Gwénaëlle Le Gall, Christopher J. Morris, Sarah V. Harding, Michael McArthur
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Burkholderia pseudomallei is the causative agent of the tropical disease, melioidosis. It is intrinsically resistant to many antimicrobials and treatment requires an onerous regimen of intravenous and orally administered drugs. Relapse of disease and
Externí odkaz:
https://doaj.org/article/0101f21e0e53457f82fc61a592924bb5
Autor:
Thomas D. Troth, Ross S. McInnes, Steven J. Dunn, Jeremy Mirza, Annalise H. Whittaker, Sarah A. Goodchild, Nicholas J. Loman, Sarah V. Harding, Willem van Schaik
Publikováno v:
PLoS ONE, Vol 18, Iss 12 (2023)
Externí odkaz:
https://doaj.org/article/1367dcccf557459994a7c63ba0045ff3
Autor:
Kay B. Barnes, Marc Bayliss, Carwyn Davies, Mark I. Richards, Thomas R. Laws, Andreas Vente, Sarah V. Harding
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Burkholderia mallei, the causative agent of glanders, is principally a disease of equines, although it can also infect humans and is categorized by the U.S. Centers for Disease Control and Prevention as a category B biological agent. Human cases of g
Externí odkaz:
https://doaj.org/article/65b439ec2bce445b839620f425b81232
Publikováno v:
Antibiotics, Vol 12, Iss 7, p 1096 (2023)
This study determined the in vitro activity of finafloxacin against panels of bacterial strains, representative of those associated with infection in cystic fibrosis patients and predominately isolated from clinical cases of respiratory disease. Many
Externí odkaz:
https://doaj.org/article/d27cfcc8b3da418f8ae701b4b32bf37d
Autor:
Adam O. Whelan, Ian Cooper, Nicola Ooi, David Orr, Kevin Blades, James Kirkham, Amanda Lyons, Kay B. Barnes, Mark I. Richards, Anne-Marie Salisbury, Mark Craighead, Sarah V. Harding
Publikováno v:
Antibiotics, Vol 12, Iss 6, p 983 (2023)
Antimicrobial resistance is a global issue, and the investigation of alternative therapies that are not traditional antibiotics are warranted. Novel bacterial type II topoisomerase inhibitors (NBTIs) have recently emerged as a novel class of antibiot
Externí odkaz:
https://doaj.org/article/6d05f97764de41768e12f6520ccf2f5f
Autor:
Michelle Nelson, Kay B. Barnes, Carwyn H. Davies, Christopher K. Cote, J. Matthew Meinig, Sergei S. Biryukov, David N. Dyer, Ondraya Frick, Henry Heine, Denise A. Pfefferle, Amanda Horstman-Smith, Julie Barbaras, Sarah V. Harding
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 506 (2023)
Burkholderia pseudomallei, the causative agent of the disease melioidosis, has been isolated from the environment in 45 countries. The treatment of melioidosis is complex, requiring lengthy antibiotic regimens, which can result in the relapse of the
Externí odkaz:
https://doaj.org/article/c25b9392bed3404bb724de9c85736d57