Zobrazeno 1 - 10
of 47
pro vyhledávání: '"V. G. Bezlepkin"'
Publikováno v:
Biophysics. 64:528-532
—The effects of X-ray exposure on the mitochondrial genome were studied in the offspring of female mice exposed in the preconception period at doses of 0.5 and 2 Gy. Radiation effects were evaluated by the proportion of offspring with a 4974-bp mtD
Autor:
V. N. Antipova, Kirillova En, L. V. Malakhova, Sokolova Sn, M. G. Lomaeva, M L Zakharova, V. G. Bezlepkin
Publikováno v:
Biophysics. 61:1026-1032
The levels of large deletions in the mitochondrial DNA of workers at the Mayak Production Association (Mayak PA) who were exposed to external and combined occupational (external γ- and internal α-rays) radiation during the course of their duties we
Autor:
V. S. Skosyrev, Vasil'eva Gv, V. N. Antipova, V. G. Bezlepkin, L. V. Malachova, M. G. Lomaeva
Publikováno v:
Russian Journal of Genetics. 49:464-469
"GelAnalyzer" software, which is used to identify and correctly compare DNA fingerprints consisting of a large number of discrete bands, has been developed by the project to study the quantitative changes in DNA polymorphism patterns in animals and h
Autor:
Kirillova En, V. G. Bezlepkin, V. N. Antipova, Soboleva IIu, M. G. Lomaeva, L. V. Malakhova, Azhub I. Gaziev, Fomenko La, M L Zakharova, Sokolova Sn
Publikováno v:
Радиационная биология. Радиоэкология. 53:25-32
Long-term post-radiation changes in the level of microsatellite DNA polymorphism in peripheral blood of the male "Mayak" employees (Ozyorsk, Russia), who had been exposed to prolonged gamma-irradiation during professional activities, were studied. DN
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 56(2)
Evidence is presented indicating the differences in the polymorphism of microsatellite (MCS) repeats in DNA of somatic tissues in the offspring of BALB/c mice of different sex born from preconceptionally irradiated males or females. Brother-sister gr
Publikováno v:
Bulletin of Experimental Biology and Medicine. 152:431-434
Sibs groups of F1-offspring born by non-irradiated mice and by female mice exposed to X-ray radiation in preconceptive period (50-200 cGy) were compared. Arbitrary primed PCR revealed significantly increased polymorphism of simple DNA repeats in soma
Publikováno v:
Russian Journal of Genetics. 47:1221-1226
The level of genome instability (GI) was studied in the progeny of female mice exposed in the preconceptional period to radiation doses of 0.5, 1, and 2 Gy in comparison to that in the progeny of the same parent pairs born before irradiation of the f
Publikováno v:
Biophysics. 56:423-428
Large mtDNA deletions in mouse brain and spleen cells, induced by X-radiation at doses of 2 and 5 Gy were studied within four weeks after the exposure of animals to X-rays. Variations in the content of extra-cellular deleted mtDNA were examined in th
Publikováno v:
Biophysics. 55:142-147
Mutations in brain mtDNA of mice X-irradiated to 5 Gy were determined using a mismatch-specific endonuclease (CEL I) and by temporal temperature gradient gel electrophoresis (TTGE). The CEL I nuclease method allows simultaneous analysis of multiple D
Publikováno v:
Biomeditsinskaya Khimiya. 56:517-525
Quantitative and qualitative changes in circulating extracellular DNA (ec-DNA) of blood plasma are considered as markers for diagnosis and prognostic of tumor pathology. We investigated the content of mutant copies of the circulating extracellular mi