Zobrazeno 1 - 10
of 94
pro vyhledávání: '"V. Faberová"'
Autor:
D. Mihalová, Mária Ďurišová, Z. Kállay, Katarína Bauerová, P. Bohov, Štefan Bezek, Tomas Trnovec, V. Faberová, V. Koprda, V. Ščasnár, M. Kukan, L. Šortés
Publikováno v:
Life Sciences. 65:2003-2005
The aim of this paper is to provide a brief overview of most important results of stobadine kinetic studies in rats, dogs, and human volunteers. In these studies, stobadine dihydrochloride and stobadine dipalmitate was used for intravenous and oral a
Autor:
Svec P, E. Andelova, Attila Ziegelhöffer, D. Pancza, Adriana Adameova, Táňa Ravingerová, Magdaléna Kuželová, V. Faberová
Publikováno v:
Molecular and cellular biochemistry. 295(1-2)
Both, diabetes mellitus (DM) and hypercholesterolemia (HCH) are known as risk factors of ischemic heart disease, however, the effects of experimental DM, as well as of HCH alone, on ischemia/reperfusion-induced myocardial injury are not unequivocal.
Publikováno v:
Die Pharmazie. 60(9)
The use of inhibitors of enzyme acyl-CoA: cholesterol acyltransferase (ACAT) seems to be a novel potential approach for a therapeutic treatment of dyslipidaemias and atherosclerosis. VULM 1457 is an ACAT inhibitor, which has expressed potent hypolipi
Autor:
M Zemánek, Michal Dubovický, A. Gajdošík, Ladislav Šoltés, V. Eybl, Eduard Ujházy, V. Faberová
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 22(9)
The distribution of [ 3 H]-stobadine, a pyridoindole antioxidant, was investigated in New Zealand white rabbits and their fetuses on days 20 and 27 of gestation. The concentrations of [ 3 H]-stobadine were determined in maternal and fetal organs afte
Publikováno v:
General physiology and biophysics.
The tolerance of the new calcium antagonist VULM 993 was investigated in a series of toxicological studies. The following results were obtained: the maximum tolerated oral dose in acute toxicity was 10,000 mg/kg for mice and 6600 mg/kg for rats, for
Autor:
Adriana Adameova, Attila Ziegelhöffer, Magdaléna Kuželová, E. Andelova, Táňa Ravingerová, Ján Styk, Svec P, D. Pancza, V. Faberová
Publikováno v:
Journal of Molecular and Cellular Cardiology. 40:957-958
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 18(7)
The effect of propentofylline on regional [3H]-leucine incorporation into brain proteins was investigated during early reperfusion following permanent occlusion of vertebral arteries and reversible occlusion of the common carotid arteries of awake ra
Publikováno v:
Molecular and chemical neuropathology. 25(2-3)
The authors studied the effects of a combination of pentoxifylline and nimodipine on cerebral lipid peroxidation in postischemic rat brain. Pentoxifylline (40 mg/kg) and nimodipine (3 mg/kg) were administered per os 30 min before 5 min of ischemia (f
Publikováno v:
Ceskoslovenska fysiologie. 44(1)
Stobadine (STB), a cardioprotective drug, was investigated for its placental transfer in rabbits on the 20th and 27th day of gestation. The concentration of 3H-STB and its metabolites was determined in maternal and foetal plasma and organs at 0.5; 1;
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 17(3)
The pharmacokinetics of heptacaine, N-(2-(2-heptyloxyphenylcarbamoyloxy)ethyl)-piperidinium chloride, a new long-acting potent carbanilate type local anaesthetic, proposed for local anaesthesia in complex treatment of hemorrhoids, was studied followi