Výsledky vyhledávání - "V. E. Blokhin"

Changes in the Content of Sphingolipids in the Nigrostriatal Dopaminergic System in the Brain of Mice with a Neurotoxic Model of Parkinson’s Disease

Autor: M. A. Shupik, Olga A. Maloshitskaya, S A Sokolov, V. E. Blokhin, U A Gutner, Albert T. Lebedev, A. V. Alessenko, Michael V. Ugrumov

Publikováno v: Neurochemical Journal. 15:175-180

—It was shown that sphingolipids are necessary for the normal functioning of neurons, and disturbance of their metabolism accompanies the development of brain diseases, including Parkinson’s disease (PD). Since the possibilities for studying the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6cdd02ee4b6c85e7c8238bfc19ab231
https://doi.org/10.1134/s1819712421020021

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Alpha-Synuclein in the Blood of Mice in a Neurotoxic Model of Parkinson’s Disease

Autor: M. V. Ugryumov, V. E. Blokhin

Publikováno v: Neurochemical Journal. 15:18-23

—One of the priorities of neuroscience is the fight against socially relevant neurodegenerative diseases, including Parkinson’s disease (PD). Given the limited possibilities of studying the pathogenesis of this disease, the creation and detailed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebc4a6296e8429b4b2dff55cbccfa998
https://doi.org/10.1134/s1819712421010025

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The Neuroprotective Effect of N-Docosahexaenoyldopamine on Degenerating Dopaminergic Neurons of the Mesencephalon

Autor: A. I. Sturova, G. N. Zinchenko, E. R. Mingazov, Natalia Gretskaya, V. E. Blokhin, Michael V. Ugrumov, Vladimir V. Bezuglov, S. A. Surkov

Publikováno v: Biology Bulletin. 47:466-473

This study was aimed at evaluating the neuroprotective effect of N-docosahexaenoyldopamine (DHA-DA), an endogenous bioactive lipid of the neurolipin family, on mesencephalic dopaminergic neurons of mouse fetuses in a cell culture under exposure to 1-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::964ef9c836456ae8f9adbb0c1d2db446
https://doi.org/10.1134/s1062359020050106

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Dopamine Synthesis by Non-Dopaminergic Neurons in the Stratium of Mice with and without Degeneration of the Nigrostriatal Dopaminergic System

Autor: V. E. Blokhin, M. V. Ugryumov, T. S. Pronina

Publikováno v: Neurochemical Journal. 14:43-48

—In the past 15 years, it has been shown that dopamine (DA) is synthesized in the brain not only by dopaminergic neurons but also by non-dopaminergic neurons expressing one of the complementary enzymes tyrosine hydroxylase or aromatic L-amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db3913f06d7d45c07987506548f4daab
https://doi.org/10.1134/s1819712420010043

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[Development of early diagnosis of Parkinson's disease based on the search for biomarkers such as premotor symptoms and changes in blood]

Autor: Michael V. Ugrumov, Gusev Ei, M. A. Shupik, S A Sokolov, U A Gutner, D. A. Katunin, A. V. Alesenko, Malykhina Ea, Olga A. Maloshitskaya, V. G. Kucheryanu, M. R. Nodel, A. L. Kalinkin, N V Titova, V. E. Blokhin, M. Yu. Martinov, E A Katunina, E. N. Pavlova

Publikováno v: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 120(12)

To determine changes in the chemical composition of blood plasma in subjects at risk of Parkinson's disease (PD) at the prodromal stage compared with age control.Subjects at risk were selected for the presence of characteristic premotor symptoms, inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14442ada431563ba02e041eeaf6c2548
https://pubmed.ncbi.nlm.nih.gov/33459535

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Development of early diagnosis of Parkinson’s disease and comprehensive economic analysis of the effect of its implementation

Autor: A V Alesenko, T. S. Pronina, S A Vartanov, Gusev Ei, A. L. Kalinkin, M Yu Martynov, I A Denisova, S A Sokolov, T V Chubarova, M. R. Nodel, V. G. Kucheryanu, Victor Polterovich, V. E. Blokhin, M. A. Shupik, M V Shakleina, E A Katunina, M. V. Ugryumov, E. N. Pavlova

Publikováno v: Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 121:9

The paper summarizes the literature and author's data on the development of early (preclinical) diagnosis of Parkinson's disease (PD). Implementation of this diagnosis will promote the use of preventive therapy and change investments in diagnosis and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d88643cb46ec64017ce0cf1b80159d
https://doi.org/10.17116/jnevro20211210119

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