Zobrazeno 1 - 10
of 29
pro vyhledávání: '"V. Dodokhov"'
Autor:
Nadezhda I. Pavlova, Aleksey A. Bochurov, Vladislav A. Alekseev, Aleksandra T. Diakonova, Vladimir V. Dodokhov, Khariton A. Kurtanov
Publikováno v:
International Journal of Biomedicine, Vol 12, Iss 1, Pp 151-154 (2022)
The aim of this study was to investigate the relationship between the HTR2A 1438A/G (rs6311) SNP and the risk of nicotine addiction in Yakuts. Methods and Results: A total of 292 people of Yakut nationality were tested (77 women and 215 men). Two g
Externí odkaz:
https://doaj.org/article/8f3bcd1616b64f4cb710c6cd704d590f
Autor:
Nadezhda I. Pavlova, Aleksey A. Bochurov, Vladislav A. Alekseev, Aleksandra T. Diakonova, Vladimir V. Dodokhov, Khariton A. Kurtanov
Publikováno v:
International Journal of Biomedicine, Vol 12, Iss 1, Pp 155-159 (2022)
Background: Genome-wide association studies identified the region of chromosome 3p21.31 as having the strongest association with the severe COVID-19 and susceptibility to SARS-CoV-2 infection. The aim of our study was to investigate the frequency of
Externí odkaz:
https://doaj.org/article/a1ed268956904b228a31c1a49391d3c3
Autor:
Aleksandra T. Diakonova, Nadezhda I. Pavlova, Vladislav A. Alekseev, Lyubov S. Mironova, Khariton A. Kurtanov, Vladimir V. Dodokhov, Innokenty D. Ushnitsky
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss 4, Pp 576-580 (2021)
The aim of our study was to investigate the relationship between the MDR1 and MTHFR gene polymorphisms and non-syndromic cleft lip with or without cleft palate (NSCL/P) in the Yakut population in the Republic of Sakha (Yakutia). Methods and Results:
Externí odkaz:
https://doaj.org/article/c306a2ec034a472fbd003ce7154fc1da
Autor:
Nadezhda I. Pavlova, Aleksandra T. Diakonova, Vladislav A. Alekseev, Lyubov S. Mironova, Vladimir V. Dodokhov, Khariton A. Kurtanov, Innokenty D. Ushnitsky
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss 4, Pp 570-575 (2021)
Background: Non-syndromic cleft lip with or without cleft palate (NSCL/P) is one of the most common birth defects. NSCL/P can be broadly divided into cleft lip only (CLO), cleft palate only (CPO), and cleft lip with cleft palate (CLP) based on clinic
Externí odkaz:
https://doaj.org/article/b7e43c3a241e4d7eab6a130116963db8
Autor:
Nadezhda I. Pavlova, Aleksandra T. Diakonova, Vladislav A. Alekseev, Lyubovy A. Sydykova, Nadezhda E. Maksimova, Zoya A. Rudykh, Yana V. Chertovskikh, Dmitry A. Sychev, Vladimir V. Dodokhov, Tuyara I. Dmitrieva, Khariton A. Kurtanov
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss 3, Pp 355-360 (2021)
The goal of this study was to investigate the distribution of alleles and genotypes of the KCNJ11 rs5219, PPARG rs1801282, TCF7L2 rs7903146/rs12255372 SNPs in Yakuts with T2D, in comparison with other ethnic populations. Methods and Results: The stu
Externí odkaz:
https://doaj.org/article/456ba0290dfc4845a986cc0fcb9bc335
Autor:
Nadezhda I. Pavlova, Aleksandra T. Diakonova, Vladislav A. Alekseev, Yigulana P. Borisova, Vladimir V. Dodokhov, Tuyara I. Dmitrieva, Khariton A. Kurtanov
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss 3, Pp 367-371 (2021)
Background: The ABCB1 gene is responsible for resistance to various cytotoxic drugs. The product of the ABCB1 gene, P-glycoprotein (P-gp), acts as a transmembrane pump and influences the action of many drugs. More than 40 SNPs of the ABCB1 gene that
Externí odkaz:
https://doaj.org/article/0f12b25b405c44a48861f88b288d20db
Autor:
Khariton A. Kurtanov, Nadezhda I. Pavlova, Aleksandra T. Diakonova, Lyubovy A. Sydykova, Sardana V. Markova, Vladimir V. Dodokhov
Publikováno v:
International Journal of Biomedicine, Vol 10, Iss 4, Pp 438-441 (2020)
Background: The pathogenetic mechanisms of type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD) are closely related. Currently, multiple studies have demonstrated a link between the PNPLA3 148M variant and the development and progressi
Externí odkaz:
https://doaj.org/article/5441dcd84bb640d7bae062f5635205b1
Autor:
Khariton A. Kurtanov, Nadezhda I. Pavlova, Aleksandra T. Diakonova, Lyubovy A. Sydykova, Tuyara N. Aleksandrova, Yigulana P. Borisova, Vladimir V. Dodokhov
Publikováno v:
International Journal of Biomedicine, Vol 10, Iss 4, Pp 433-437 (2020)
Background: The first GWAS searching for such genetic factors identified the PNPLA3 gene as a major genetic determinant for the predisposition to nonalcoholic fatty liver disease in Hispanic, African American, and European American populations, accor
Externí odkaz:
https://doaj.org/article/e2ee0a72f1bb43e18380258b449d1369
Autor:
Nadezhda I. Pavlova, Khariton A. Kurtanov, Aleksandra T. Diakonova, Lyubov S. Mironova, Natalia A. Solovyeva, Yigulana P. Borisova, Vladimir V. Dodokhov, Innokenty D. Ushnitsky
Publikováno v:
International Journal of Biomedicine, Vol 10, Iss 1, Pp 50-53 (2020)
Background: The aim of this study was to search for associations between polymorphisms of the IRF6, MDR1, and MTHFR genes and the risk of congenital orofacial cleft (OFCs) among the population of the Republic of Sakha (Yakutia). Methods and Results:
Externí odkaz:
https://doaj.org/article/3392a71ebe4b419f944cb3bed6a9f57a
Autor:
Kh. A. Kurtanov, L. A. Sydykova, N. I. Pavlova, N. P. Filippova, V. V. Dodokhov, G. A. Apsolikhova, N. A. Solov'eva, A. T. D'yakonova, L. M. Neustroeva, M. A. Varlamova, N. V. Borisova
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 46, Iss 3, Pp 258-263 (2018)
Rationale: The association of rs738409 I148M polymorphism with type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease has been confirmed for several ethnic and territorial groups. Up to now, no such studies have been performed in the p
Externí odkaz:
https://doaj.org/article/af7b428718d3418181294bfbd9e9a8b6