Zobrazeno 1 - 10
of 15
pro vyhledávání: '"V. D. Gusarova"'
Autor:
V. D. Gusarova, M. S. Pantyushenko, V. M. Simonov, R. R. Shukurov, R. A. Khamitov, A. Yu. Vishnevskiy
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 19, Iss 1, Pp 39-49 (2019)
Recombinant tissue plasminogen activator (international nonproprietary name — alteplase) which was developed by «GENERIUM» (Russia) and received a marketing authorisation in Russia is completely analogous to Actilyse® which is used to treat medi
Externí odkaz:
https://doaj.org/article/de43b67d77524d59972f919586d09234
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 2, Pp 80-84 (2019)
The article discusses the development of a production technique for recombinant follicle-stimulating hormone used in the treatment of infertility, in the culture of Chinese hamster ovary cells. As part of the creation of the technological platform re
Externí odkaz:
https://doaj.org/article/1d44f86e9a6b4a849cf6927231a41100
Autor:
T. V. Budylskaya, D. V. Byrikhina, A. I. Gosudarev, V. D. Gusarova, F. M. Izhaeva, P. V. Mikhailov, D. A. Gusarov
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 0, Iss 1, Pp 74-85 (2019)
Biopharmaceuticals intended for gene therapy are mostly presented by supercoiled plasmid DNA obtained with bacteria cell lines. The properties of their formulations, including stability under different storage conditions, are barely studied. This art
Externí odkaz:
https://doaj.org/article/76a0936eb59442f9b13f8218878d28d5
Autor:
D. A. Gusarov, A. F. Mironov, P. V. Mikhailov, F. M. Izhaeva, V. I. Shvets, T. A. Budyl’skaya, V. D. Gusarova, A. I. Gosudarev, D. V. Byrikhina
Publikováno v:
Pharmaceutical Chemistry Journal. 48:822-829
The development of domestic biogenerics to replace imported drugs is among the main goals of the Pharma-2020 strategy. Insulin glargine, a therapeutic polypeptide with sustained glycolytic activity, is one of the most important biogenerics. A systema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23d555b8b7207ab0384e19c6d778a161
https://doi.org/10.1007/s11094-015-1203-2
https://doi.org/10.1007/s11094-015-1203-2
Autor:
S. A. Kosarev, E. D. Shibanova, V. D. Gusarova, E. A. Evteeva, T. V. Vorob’eva, D. A. Gusarov, D. I. Bairamashvili, I. V. Sokolova
Publikováno v:
Pharmaceutical Chemistry Journal. 46:234-240
Much attention is presently devoted to the treatment of lymphoma using monoclonal antibodies. Unfortunately, preparations such as Rituximab (MabThera) are not produced in the Russian Federation and must be imported from abroad. It was shown that H1-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::296b950bd72bc9466defd202a549e178
https://doi.org/10.1007/s11094-012-0769-1
https://doi.org/10.1007/s11094-012-0769-1
Publikováno v:
Journal of Chromatography B. 877:1216-1220
HPLC plays a key role in the preparative purification of human insulin. A21-desamidoinsulin is one of the impurities that possesses the chromatographic behavior similar to that of insulin and hence separation from this by-product is rather difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecce62a1b6f6c748255b94116915e61
https://doi.org/10.1016/j.jchromb.2009.02.062
https://doi.org/10.1016/j.jchromb.2009.02.062
Autor:
D. A. Gusarov, D. I. Bairamashvili, N. K. Senatorova, A. V. Mikhalev, V. D. Gusarova, V. A. Lasman, A. F. Mironov, A. V. Senatorov
Publikováno v:
Russian Journal of Bioorganic Chemistry. 35:47-53
A method for monitoring the manufacture of human insulin by HPLC was developed. The method was validated by the estimation of its linearity, accuracy, precision, specificity, and robustness; the limits of detection and quantitative assessment were al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f48dbc6bfa698d5138f2e67fea69fdd1
https://doi.org/10.1134/s1068162009010063
https://doi.org/10.1134/s1068162009010063
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 2:356-366
Studies of replacement therapy of diabetes mellitus resulted not only in introduction of series of forms of insulin available at pharmaceutical market but also in new insulin analogues, which exhibit better control of blood glucose level. The present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03aef67c8351a19f0e1cf802c08f7409
https://doi.org/10.1134/s1990750808040057
https://doi.org/10.1134/s1990750808040057
Autor:
D A, Gusarov, V D, Gusarova, A V, Mikhalev, V A, Lasman, D I, Bairamashvili, A F, Mironov, N K, Senatorova, A V, Senatorov
Publikováno v:
Bioorganicheskaia khimiia. 35(1)
A method for monitoring the manufacture of genetically engineered human insulin by HPLC was developed. The method was validated by the estimation of its linearity, correctness, accuracy, specificity, and stability; the limits of detection and quantit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c72c3c25b27028694f620dc5c8c3d178
https://pubmed.ncbi.nlm.nih.gov/19377522
https://pubmed.ncbi.nlm.nih.gov/19377522
Publikováno v:
Biomeditsinskaia khimiia. 54(6)
Studies of replacement therapy of diabetes mellitus resulted in introduction of series of forms of insulin and new insulin analogs which exhibit better control of blood glucose level. The present paper deals with basic tendencies in this field.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b4e878d4094a66527c820f9da13dc0d
https://pubmed.ncbi.nlm.nih.gov/19205422
https://pubmed.ncbi.nlm.nih.gov/19205422