Zobrazeno 1 - 10
of 53
pro vyhledávání: '"V. Cassella"'
Publikováno v:
BJPsych Open, Vol 3, Pp 285-290 (2017)
Background Efficacy of inhaled loxapine 5 or 10 mg in treating agitation was shown using the Positive and Negative Syndrome Scale – Excited Component (PANSS-EC) in two Phase III randomised, double-blind, placebo-controlled trials in 344 agitated p
Externí odkaz:
https://doaj.org/article/6badc39d965b45a5ac3181c15e9dc614
Autor:
Crystal Aguh, Eric Ghorayeb, Justine Koenigsberg, Steven Fakharzadeh, Natasha Atanaskova Mesinkovska, Lynne Napatalung, Justin M. Ko, Amy J. McMichael, Amy S. Paller, Fabio P. Nunes, Carolyn Goh, Paradi Mirmirani, Melissa Piliang, Amy M. DeLozier, Maryanne M. Senna, Kristen Lo Sicco, Chesahna Kindred, Pedram Yazdan, Antonella Tosti, Wilma F. Bergfeld, Maria K. Hordinsky, Brittany G. Craiglow, Kavita Gandhi, Marc Glashofer, Jerry Shapiro, Leslie Castelo-Soccio, Kathie P. Huang, Gurpreet Ahluwalia, Brett A. King, James V. Cassella, Julian Mackay-Wiggan
Publikováno v:
Journal of the American Academy of Dermatology. 86:359-364
Background The current classification for alopecia areata (AA) does not provide a consistent assessment of disease severity. Objective To develop an AA severity scale based on expert experience. Methods A modified Delphi process was utilized. An advi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69242a093be48db2de4f58b7a7f9e3c8
https://doi.org/10.1016/j.jaad.2021.08.043
https://doi.org/10.1016/j.jaad.2021.08.043
Autor:
Brett A. King, Natasha Atanaskova Mesinkovska, Paradi Mirmirani, Justin M. Ko, James V. Cassella
Publikováno v:
Journal of Investigative Dermatology Symposium Proceedings. 20:S62-S68
Previous QOL and disease burden studies have not captured all relevant aspects of living with alopecia areata (AA). To better understand the burden and everyday experience of living with moderate-to-severe AA, a cross-sectional, online, quantitative-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cac393e81172e197ec026efe832762f8
https://doi.org/10.1016/j.jisp.2020.05.007
https://doi.org/10.1016/j.jisp.2020.05.007
Akademický článek
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Autor:
Brett King, Natasha Mesinkovska, Paradi Mirmirani, Suzanne Bruce, Steve Kempers, Emma Guttman-Yassky, Janet L. Roberts, Amy McMichael, Maria Colavincenzo, Colleen Hamilton, Virginia Braman, James V. Cassella
Publikováno v:
Journal of the American Academy of Dermatology. 87(2)
Janus kinase (JAK) activation is suggested to have a pathological role in alopecia areata (AA). CTP-543, a deuterated compound that selectively inhibits JAK1 and JAK2, is being developed as an oral treatment for AA.To assess the safety and efficacy o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d9acdb826f9b872adac7b32f4c657d
https://pubmed.ncbi.nlm.nih.gov/35364216
https://pubmed.ncbi.nlm.nih.gov/35364216
Publikováno v:
BJPsych Open
Background Efficacy of inhaled loxapine 5 or 10 mg in treating agitation was shown using the Positive and Negative Syndrome Scale – Excited Component (PANSS-EC) in two Phase III randomised, double-blind, placebo-controlled trials in 344 agitated pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b79e3204cde3329f17d563f7a91f2860
https://doi.org/10.1192/bjpo.bp.117.005363
https://doi.org/10.1192/bjpo.bp.117.005363
Autor:
James V. Cassella, Daniel Friedman, John R. Pollard, Robert T. Wechsler, Jacqueline A. French, Edwin S. Kamemoto, Jouko I. T. Isojärvi, Lily Gong, Michael A. Gelfand, Blanca Vazquez
Publikováno v:
Epilepsia. 60(8)
Objective Treatment options for seizure clusters are limited; the need for easy-to-administer treatments remains. The Staccato system delivers drug deep into the lung via inhalation. In this phase 2a study, we investigated the ability of three differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77dd5200934e05e092fd5eae70738e8c
https://pubmed.ncbi.nlm.nih.gov/31268555
https://pubmed.ncbi.nlm.nih.gov/31268555
Publikováno v:
International Journal of Clinical Pharmacology and Therapeutics
Objective This randomized, double-blind, active- and placebo-controlled, crossover, thorough QT study assessed the effect of two inhaled loxapine doses on cardiac repolarization as measured by corrected QT (QTc) interval in healthy subjects (Clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4d8071a9744fe09ac5ffc982ef36930
http://europepmc.org/articles/PMC4611162
http://europepmc.org/articles/PMC4611162
Publikováno v:
Journal of Clinical Pharmacology
This randomized, double‐blind, placebo‐controlled, parallel‐group study was to determine the pharmacokinetic characteristics, safety, and tolerability of multiple doses of inhaled loxapine aerosol in subjects on a stable, oral, chronic antipsyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5870bfde814f5d0709dfe642e8d0ef1
http://europepmc.org/articles/PMC5029575
http://europepmc.org/articles/PMC5029575
Autor:
Sally Selim, Laura Rabinovich-Guilatt, Alexander A. Vinks, Tsuyoshi Fukuda, Mark A. Smith, Min Dong, James V. Cassella
Loxapine for inhalation is a drug-device combination product approved in adults for the acute treatment of agitation associated with schizophrenia or bipolar I disorder. The primary objective of this study was to develop a clinical trial protocol to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1a06a2280c7375a2f5d9f244046722
https://europepmc.org/articles/PMC5557705/
https://europepmc.org/articles/PMC5557705/
