Zobrazeno 1 - 10
of 29
pro vyhledávání: '"V. C. Broaddus"'
Autor:
Philip C. Hopewell, V C Broaddus
Publikováno v:
The International Journal of Tuberculosis and Lung Disease. 24:654-655
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::855b94c07e13f7b43fb9d135036c71ab
https://doi.org/10.5588/ijtld.20.0268
https://doi.org/10.5588/ijtld.20.0268
Autor:
V. C. Broaddus, Milena Marques Pagliarelli Acencio, Carlos Sergio Rocha Silva, Lisete R. Teixeira, Evaldo Marchi, Barbara Soares
Publikováno v:
Lung. 193:831-837
Several diseases have been related to asbestos exposure, including the pleural tumor mesothelioma. The mechanism of pleural injury by asbestos fibers is not yet fully understood. The inflammatory response with release of mediators leading to a dysreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc50263f8bad9f57efc3860fa6cf05fe
https://doi.org/10.1007/s00408-015-9744-4
https://doi.org/10.1007/s00408-015-9744-4
Autor:
Michele Carbone, V. C. Broaddus, Anne Tsao, M. C. Jaurand, G. Hillerdal, Bruce W. S. Robinson, Raja M. Flores, Harvey I. Pass, Steven M. Albelda, Kristina Kjærheim
Publikováno v:
Oncogene. 26:6959-6967
The eighth International Mesothelioma Interest Group (IMIG) meeting was held in Chicago, IL, United States, in 19–22 October 2006 to discuss mesothelioma – the cancer often linked to asbestos exposure. It is a very aggressive malignancy with a me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88fbc7279557dd5ebef86e23c0a844d0
https://doi.org/10.1038/sj.onc.1210515
https://doi.org/10.1038/sj.onc.1210515
Inhibition of autophagy sensitizes malignant pleural mesothelioma cells to dual PI3K/mTOR inhibitors
Autor:
Gabriela Ziltener, Emanuela Felley-Bosco, Dario Barbone, Walter Weder, V C Broaddus, Rolf A. Stahel, Nohemy Echeverry
Publikováno v:
Cell Death & Disease
Cell death & disease
Cell death & disease
Malignant pleural mesothelioma (MPM) originates in most of the cases from chronic inflammation of the mesothelium due to exposure to asbestos fibers. Given the limited effect of chemotherapy, a big effort is being made to find new treatment options.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8e8a892542c0a7af209f1051b3c7bb
https://pubmed.ncbi.nlm.nih.gov/25950487
https://pubmed.ncbi.nlm.nih.gov/25950487
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 25:111-118
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can induce apoptosis in certain tumor cells. In addition, TRAIL and chemotherapy can act cooperatively, possibly as a result of chemotherapy-induced increases in expression of a TRAIL re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb0a1ae897d9d68926de98e831033c7
https://doi.org/10.1165/ajrcmb.25.1.4472
https://doi.org/10.1165/ajrcmb.25.1.4472
Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen species
Publikováno v:
Journal of Clinical Investigation. 98:2050-2059
Mesothelial cells, the progenitor cell of the asbestos-induced tumor mesothelioma, are particularly sensitive to the toxic effects of asbestos, although the molecular mechanisms by which asbestos induces injury in mesothelial cells are not known. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f5d195b5baa6ec63f85a9c3505bc5f
https://doi.org/10.1172/jci119010
https://doi.org/10.1172/jci119010
Publikováno v:
Journal of Clinical Investigation. 96:1987-2001
The mechanism by which pleural mesothelial cells, the likely progenitor cells of asbestos-induced mesothelioma, recognize and internalize crocidolite asbestos is unknown. Because incubation of asbestos fibers with serum increases their association wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d906e6461addddc9124137b7eb3e1c68
https://doi.org/10.1172/jci118246
https://doi.org/10.1172/jci118246
Autor:
V. C. Broaddus
Publikováno v:
Seminars in Respiratory and Critical Care Medicine. 16:303-314
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dbceb9eaacd641a43cf4dfd4fdb64db
https://doi.org/10.1055/s-2007-1009841
https://doi.org/10.1055/s-2007-1009841
Autor:
V C Broaddus
Macrophages are the first inflammatory cells to respond to asbestos fibers and we have shown that they are the predominant inflammatory cell in the asbestos-induced tumor, mesothelioma. We are beginning to unravel the role of the macrophage in this i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::082d7dd5183697e95c54dfa5323de86f
https://doi.org/10.21236/ada582550
https://doi.org/10.21236/ada582550
Autor:
M. Sadick, A. M. Boylan, J. M. Hoeffel, Wai Lee Wong, Anan Chuntharapai, K. T. Hartiala, V. C. Broaddus, Caroline Hebert
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 267:L137-L144
Gram-negative endotoxin induces production of the potent chemotactic factor interleukin-8 (IL-8) in vitro; however, the importance of IL-8 in endotoxin-induced inflammation in vivo is unknown. We asked whether IL-8 is an important contributor to chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0398f0da2f7cc6129ac7460ff823bbd
https://doi.org/10.1152/ajplung.1994.267.2.l137
https://doi.org/10.1152/ajplung.1994.267.2.l137