Zobrazeno 1 - 10 of 42 pro vyhledávání: '"V. Brechler"'
1
Miniglucagon [glucagon-(19-29)] is a component of the positive inotropic effect of glucagon
Autor: Alain Kervran, Philippe Blache, V. Brechler, Dominique Bataille, Catherine Pavoine, Françoise Pecker, Dung Le-Nguyen, S. Laurent
Publikováno v: American Journal of Physiology-Cell Physiology. 260:C993-C999
Glucagon is well known for its cardiotonic effect, but its mechanism of action remains undetermined. In the present study, we showed that glucagon, under minimal degradation conditions, had no effect on the amplitude of contractility of beating chick
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a7e490bdb7a54b9f144c0be37a0cb0
https://doi.org/10.1152/ajpcell.1991.260.5.c993
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2
The renin-angiotensin system in hybrid NG108-15 cells. Renin gene is from mouse neuroblastoma, angiotensinogen and angiotensin-converting enzyme genes are of rat glioma origin
Autor: L, Laflamme, V, Brechler, T L, Reudelhuber, N, Gallo-Payet, C F, Deschepper
Publikováno v: Regulatory peptides. 77(1-3)
Angiotensin II (Ang II) increases the level of tyrosine phosphorylation of several proteins in nondifferentiated NG108-15 cells, a hybrid derived from the fusion of mouse neuroblastoma and rat glioma cells. Conversely, incubation of NG108-15 cells wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cb1ec55e35f7ff935bf14e4f322ba803
https://pubmed.ncbi.nlm.nih.gov/9809791
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4
Angiotensin II stimulates protein tyrosine phosphatase activity through a G-protein independent mechanism
Autor: V, Brechler, S, Reichlin, M, De Gasparo, S P, Bottari
Publikováno v: Receptorschannels. 2(2)
Most of angiotensin II's (Ang II) documented effects have been attributed to the interaction of this peptide with a G-protein coupled receptor termed AT1. The role and the signalling mechanisms of the more recently characterized AT2 receptor, which d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::110e0fc078bb689490b214de2ad1605d
https://pubmed.ncbi.nlm.nih.gov/7953293
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5
Angiotensin AT2 receptor mediated inhibition of particulate guanylate cyclase: a link with protein tyrosine phosphatase stimulation?
Autor: V, Brechler, N R, Levens, M, De Gasparo, S P, Bottari
Publikováno v: Receptorschannels. 2(2)
Ever since the identification of two distinct Ang II receptor subtypes, the function of the AT2 receptor has been a subject of debate. As opposed to the AT1 subtype, this receptor does not interact with G-proteins in most cell lines and tissues. We s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d488c6c99f39b0e1490a5642fd9673f2
https://pubmed.ncbi.nlm.nih.gov/7525002
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6
Inhibition by glucagon of the cGMP-inhibited low-Km cAMP phosphodiesterase in heart is mediated by a pertussis toxin-sensitive G-protein
Autor: Françoise Pecker, Catherine Pavoine, V. Brechler, E Garbarz, Rodolphe Fischmeister, R Hanf
Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 1992, 267 (22), pp.15496-501
ResearcherID
International audience; We have recently reported that glucagon activated the L-type Ca2+ channel current in frog ventricular myocytes and showed that this was linked to the inhibition of a membrane-bound low-Km cAMP phosphodiesterase (PDE) (Méry, P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c35f4ca5584321f3f4cf9707e1f27e
https://pubmed.ncbi.nlm.nih.gov/1353495
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7
Glucagon-(19-29) exerts a biphasic action on the liver plasma membrane Ca2+ pump which is mediated by G proteins
Autor: B. Roche, Françoise Pecker, Catherine Pavoine, M. Dufour, Sophie Lotersztajn, Dominique Bataille, Dung Le-Nguyen, V. Brechler
Publikováno v: The Journal of biological chemistry. 265(17)
We have recently shown that nanomolar concentrations of glucagon-(19-29), which can derive from native glucagon by proteolytic cleavage of the dibasic doublet Arg17-Arg18, inhibit the Ca2+ pump in liver plasma membrane vesicles independently of adeny
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd73df4a9434ccb7b85ebfc0978919c
https://pubmed.ncbi.nlm.nih.gov/2141022
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8
Glucagon stimulates the cardiac Ca2+ current by activation of adenylyl cyclase and inhibition of phosphodiesterase
Autor: Catherine Pavoine, Françoise Pecker, Pierre-François Méry, Rodolphe Fischmeister, V. Brechler
Publikováno v: Nature. 345(6271)
Glucagon exerts positive inotropic and chronotropic effects in the heart. Like its glycogenolytic effect in liver cells, the cardiac effects of glucagon are often correlated with adenylyl cyclase stimulation. Therefore, cyclic AMP-dependent phosphory
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b244d8f917b7ad3c37a24f5ad90cf4
https://pubmed.ncbi.nlm.nih.gov/2159595
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9
Hormonal and Non-Hormonal Regulation of Ca2+ Current and Adenylate Cyclase in Cardiac Cells
Autor: Rodolphe Fischmeister, Françoise Pecker, V. Brechler, Alvin Shrier, Pierre-François Méry, Catherine Pavoine
Publikováno v: Developments in Cardiovascular Medicine ISBN: 9781461288138
The influx of Ca2+ ions through transmembrane Ca2+ channels is fundamental in many aspects of cardiac function. Regulation of the heart beat by noradrenaline and acetylcholine (ACh) is in part mediated by the effects of these neurotransmitters on cal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::852b4c1676272c45144ee85bb9928131
https://doi.org/10.1007/978-1-4613-1513-1_3
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