Zobrazeno 1 - 10
of 68
pro vyhledávání: '"V. Bichko"'
Publikováno v:
Journal of Engineering Science and Technology Review, Vol 7, Iss 5, Pp 9-11 (2014)
The effect of thermal-strain cycle on residual strains in thin-walled circular seams of cylindrical shells using TIG butt welds was studied. Estimates were calculated using numerical modelling. The structure was made of corrosion-resistant austenit
Externí odkaz:
https://doaj.org/article/26b8779bb3c14b0aaa09e9effc556b67
Autor:
O. V. Zozulya, O. A. Kozyrev, O. S. Efremova, E. A. Orlova-Morozova, U. A. Kuimova, E. S. Ivanova, D. B. Sonin, N. G. Zakharova, F. I. Nagimova, V. V. Bichko, N. V. Kurina, A. V. Kravchenko, T. E. Shimonova, O. S. Tonkikh, V. V. Pokrovsky, A. A. Yakovlev, O. E. Chernova, N. V. Vostokova
Publikováno v:
Infekcionnye bolezni. 15:5-13
Autor:
Pavel M. Yamanushkin, Elena A. Bulanova, O. M. Korzinov, Vadim V. Bichko, Ezhova Ev, Andrey Alexandrovich Ivashchenko, Oleg D. Mitkin, Alexandre V. Ivachtchenko
Publikováno v:
Pharmaceutical Chemistry Journal. 49:352-361
A focused library of heterocyclic compounds including a 2-aminomethyl-1H-benzimidazole (1 – 19), 2-aminomethylindole (20 – 83), benzofuran-2-ylmethylamine (84 – 92), or 2-piperazin-1-ylmethylbenzoxazole (93) fragment was screened for the abilit
Autor:
O. M. Korzinov, V. Yu. Vedenskii, Vadim V. Bichko, Andrey Alexandrovich Ivashchenko, Ya. A. Ivanenkov, Elena A. Bulanova, Oleg D. Mitkin, Ilya Okun, Alexandre Vasilievich Ivachtchenko, I. A. Leneva, V. M. Kisil, Pavel M. Yamanushkin
Publikováno v:
Pharmaceutical Chemistry Journal. 49:151-162
Novel substituted 5-hydroxy-2-aminomethyl-1H-indole-3-carboxylic acids and their derivatives were synthesized. The antiviral properties of these compounds were investigated in relation to bovine viral diarrhea virus (BVDV), hepatitis C virus (HCV), a
Autor:
Ruben N. Karapetian, Natalia A. Shevkun, I. A. Leneva, I. T. Fedyakina, Oleg D. Mitkin, Olga O. Nevolina, Mark S. Veselov, Alexandre V. Ivachtchenko, Olga V. Mokrushina, Pavel M. Yamanushkin, Yan A. Ivanenkov, Vadim V. Bichko
Publikováno v:
Journal of Antimicrobial Chemotherapy. 69:1311-1324
Received 12 August 2013; returned 21 September 2013; revised 14 November 2013; accepted 4 December 2013Objectives:Developmentofanoveldrugcandidatewithimprovedactivityagainstinfluenzavirusneuraminidase(NA) compared with currently available therapeuti
Autor:
Oleg D. Mitkin, Natalia A. Shevkun, Dmitry V. Kravchenko, Ruben N. Karapetian, Mark S. Veselov, Yan A. Ivanenkov, Elena A. Bulanova, Angela G. Koryakova, Irina V. Kuznetsova, Vadim V. Bichko, Alexandre V. Ivachtchenko, Andrey S. Trifelenkov, Nina V. Chufarova, Natalia V. Vostokova, Pavel M. Yamanushkin
Publikováno v:
Journal of medicinal chemistry. 57(18)
A series of next in class small-molecule hepatitis C virus (HCV) NS5A inhibitors with picomolar potency containing 2-pyrrolidin-2-yl-5-{4-[4-(2-pyrrolidin-2-yl-1H-imidazol-5-yl)buta-1,3-diynyl]phenyl}-1H-imidazole cores was designed based on the SAR
Autor:
Mark S. Veselov, Natalia A. Shevkun, Ruben N. Karapetian, Alexandre V. Ivachtchenko, Vadim V. Bichko, Oleg D. Mitkin, Pavel M. Yamanushkin, I. A. Leneva, Yan A. Ivanenkov, Olga V. Borisova
Publikováno v:
The Journal of antimicrobial chemotherapy. 69(7)
Objectives Development of a novel drug candidate with improved potency against influenza virus neuraminidase compared with currently available therapeutics, and high activity against oseltamivir-resistant viruses. Methods A number of synthetic compou
Publikováno v:
Journal of Virological Methods. 75:199-204
Replication of hepatitis delta virus (HDV) is dependent on delta antigen (deltaAg), an HDV-encoded protein, which binds to HDV RNA and is capable of multimerization. To characterize HDV-specific ribonucleoprotein complexes (RNP) we used electrophores
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
The small, 195-amino-acid form of the hepatitis delta virus (HDV) antigen (δAg-S) is essential for genome replication, i.e., for the transcription, processing, and accumulation of HDV RNAs. To better understand this requirement, we used purified rec
Autor:
Vadim V. Bichko, Oleg D. Mitkin, Pavel M. Yamanushkin, Yan A. Ivanenkov, Olga V. Borisova, I. A. Leneva, Alexandre V. Ivachtchenko
Publikováno v:
Antiviral research. 100(3)
A medium-sized focused library of novel Oseltamivir structural analogues with promising antiviral activity was successfully synthesized using a combinatorial approach. The synthesized compounds were then thoroughly evaluated in neuraminidase- and cel