Design of 4-(4-dialkylaminostyryl) -pyridinium dyes for fluorescent detection of amyloid fibrils

Autor: D. I. Inshyn, V. B. Kovalska, Svitlana Chernii, S. M. Yarmoluk

Publikováno v: Biopolymers and Cell, Vol 32, Iss 4, Pp 289-299 (2016)

The pathological proteins aggregation into the fibrillar structures is common to a large group of amyloid-related disorders, such as neurodegenerative diseases. Accordingly, there is a need for development of analytical tools, particularly fluorescen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7e20c143119ceee8309426f6f611c8d
http://biopolymers.org.ua/pdf/32/4/289/

Fluorescent Detection of a Partially Unfolded Conformation of Beta-Lactoglobulin Using Squaraine Dyes

Autor: V. B. Kovalska, Sergiy M. Yarmoluk, Lucinda V. Reis, Paulo F. Santos, M. Yu. Losytskyy

Publikováno v: Macromolecular Symposia. 335:43-50

Summary Six benzothiazole squaraine dyes were studied as fluorescent probes for detection of thermally-induced conformation changes of amyloidogenic protein beta-lactoglobulin (BLG). Majority of dyes have shown a strong fluorescent response when comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53683af748908b1c279adf76a8288dc4
https://doi.org/10.1002/masy.201200120

Application of MALDI-TOF mass spectrometry for study on fibrillar and oligomeric aggregates of alpha-synuclein

Autor: Sergiy M. Yarmoluk, M. Losytskyy, V. V. Cherepanov, O.V. Severinovskaya, V. B. Kovalska, Vinod Subramaniam

Publikováno v: Biopolymers and Cell, 30(3), 190-196. National Academy of Sciences of Ukraine
Severinovskaya, O V, Kovalska, V B, Losytskyy, M Y, Cherepanov, V V, Subramaniam, V & Yarmoluk, S M 2014, ' Application of MALDI-TOF mass spectrometry for study on fibrillar and oligomeric aggregates of alpha-synuclein ', Biopolymers and Cell, vol. 30, no. 3, pp. 190-196 . https://doi.org/10.7124/bc.000895
Biopolymers and cell, 30(3), 190-196. National Academy of Sciences of Ukraine
Biopolymers and Cell, Vol 30, Iss 3, Pp 190-196 (2014)

Aim. To study the -synuclein (ASN) aggregates of different structural origin, namely amyloid fibrils and spherical oligomers, in comparison with a native protein. Methods. MALDI TOF mass spectrometry and atomic for- ce microscopy (AFM). Results. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48d7ce794f5f9f337677e9c97727459
https://research.vu.nl/en/publications/8010a9ea-fde5-4a12-ab53-a2faf9581985

Interaction of cyanine dyes with nucleic acids. 10. Synthesis and spectral properties of novel benzothiazol-4-[2,6-dimethylpyridinium] raonomethyne cyanine dyes

Autor: V. B. Kovalska, D. V. Krivorotenko, S. M. Yarmoluk

Publikováno v: Biopolymers and Cell. 16:145-152

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b87708b61e93c21603c4a6cd6953b474
https://doi.org/10.7124/bc.000561

Towards the anti-fibrillogenic activity of phthalocyanines with out-of-plane ligands: correlation with self-association proneness

Autor: M. Yu. Losytskyy, I. M. Tretyakova, V. B. Kovalska, Sergiy M. Yarmoluk, V. Ya. Chernii, S. V. Volkov, Svitlana Chernii

Publikováno v: Biopolymers and Cell, Vol 29, Iss 6, Pp 473-479 (2013)

Aim. The activity of five hafnium phthalocyanines containing out-of-plane ligands as inhibitors of reaction of insulin fibril formation is studied and correlation between their inhibitory properties and tendency to self-association is discussed. Meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16186e2d136a9a53a6221809d941371
http://dspace.nbuv.gov.ua/handle/123456789/153666