Zobrazeno 1 - 10
of 17
pro vyhledávání: '"V. Alexandra Moser"'
Autor:
V. Alexandra Moser, Michael J. Workman, Samantha J. Hurwitz, Rachel M. Lipman, Christian J. Pike, Clive N. Svendsen
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103238- (2021)
Summary: Apolipoprotein E4 (APOE4) is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD). APOE4 is known to affect the function of microglia, but to what extent this gene drives microglial gene expression has thus far not been
Externí odkaz:
https://doaj.org/article/fd27aedfef3942159b202a822dc10a26
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-20 (2018)
Abstract Background Obesity exerts negative effects on brain health, including decreased neurogenesis, impaired learning and memory, and increased risk for Alzheimer’s disease and related dementias. Because obesity promotes glial activation, chroni
Externí odkaz:
https://doaj.org/article/19d67b4a48804bc2a25fbc1f070f7641
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 7 (2013)
Although stress is implicated in the pathophysiology of mood and anxiety disorders, not all individuals who suffer stressful life events develop psychopathology. Differential susceptibility to stress may be influenced by genetically-mediated differen
Externí odkaz:
https://doaj.org/article/55ceb159d2354c0d83c3dffb77c44cc7
Autor:
Alexander H. Laperle, V. Alexandra Moser, Pablo Avalos, Bin Lu, Amanda Wu, Aaron Fulton, Stephany Ramirez, Veronica J. Garcia, Shaughn Bell, Ritchie Ho, George Lawless, Kristina Roxas, Saba Shahin, Oksana Shelest, Soshana Svendsen, Shaomei Wang, Clive N. Svendsen
Publikováno v:
Stem Cell Reports.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45bff8042fe4aae7b091bb411666ebb9
https://doi.org/10.1016/j.stemcr.2023.03.016
https://doi.org/10.1016/j.stemcr.2023.03.016
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-4 (2020)
Communications Biology
Communications Biology
Parabiosis, blood exchange and plasma transfer experiments have highlighted the rejuvenating properties of young blood. Our Communications Biology study demonstrated that young bone marrow transplantation attenuates cognitive decline in old mice, wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8ed20341ac255b7c93112a8e41a819c
http://link.springer.com/article/10.1038/s42003-020-0797-4
http://link.springer.com/article/10.1038/s42003-020-0797-4
Autor:
Kristina M. Roxas, Pablo Avalos, Ivy Dang, George Y. Liu, Shuang Chen, Wenxuan Zhang, V. Alexandra Moser, Helen S. Goodridge, Catherine Bresee, Clive N. Svendsen, Marlesa Godoy, Moshe Arditi, Alberto Yáñez, Melanie Das
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-10 (2019)
Communications Biology
Communications Biology
Restoration of cognitive function in old mice by transfer of blood or plasma from young mice has been attributed to reduced C–C motif chemokine ligand 11 (CCL11) and β2-microglobulin, which are thought to suppress neurogenesis in the aging brain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7f03db53f07ce02e9bbb8f0aa8f703
http://link.springer.com/article/10.1038/s42003-019-0298-5
http://link.springer.com/article/10.1038/s42003-019-0298-5
Autor:
Clive N. Svendsen, Todd E. Morgan, Mary Jo LaDu, V. Alexandra Moser, Caleb E. Finch, Christian J. Pike, Samuel Sances
Publikováno v:
Alzheimer's & Dementia. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8740d70d8ebedeb4a8ebd4ce83d092b0
https://doi.org/10.1016/j.jalz.2019.06.046
https://doi.org/10.1016/j.jalz.2019.06.046
Publikováno v:
Frontiers in Neuroendocrinology. 43:60-82
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder for which there are no effective strategies to prevent or slow its progression. Because AD is multifactorial, recent research has focused on understanding interactions among the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019f636e51488ae9ffe0cf74cddcded9
https://doi.org/10.1016/j.yfrne.2016.09.001
https://doi.org/10.1016/j.yfrne.2016.09.001
Autor:
Amy Christensen, V. Alexandra Moser, Jiahui Liu, Shunya Yagi, Amanda Zhou, Liisa A.M. Galea, Christian J. Pike, Christopher R. Beam
Risk for Alzheimer's disease (AD) is affected by multiple factors, including aging, obesity, and low testosterone. We previously showed that obesity and low testosterone independently and interactively exacerbate AD-related outcomes in young adult ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec154e72217c49b85aed08b8b16c6fa8
https://europepmc.org/articles/PMC6252085/
https://europepmc.org/articles/PMC6252085/
Autor:
V Alexandra, Moser, Christian J, Pike
Publikováno v:
eNeuro
Alzheimer’s disease (AD) risk is modified by both genetic and environmental risk factors, which are believed to interact to cooperatively modify pathogenesis. Although numerous genetic and environmental risk factors for AD have been identified, rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ed519eaae72aba2b649a115ba618391
https://pubmed.ncbi.nlm.nih.gov/28612048
https://pubmed.ncbi.nlm.nih.gov/28612048