Zobrazeno 1 - 10
of 14
pro vyhledávání: '"V. A. Shlyakhovenko"'
Autor:
A P, Burlaka, S V, Virko, V M, Grygorenko, O А, Samoylenko, A V, Verbinenko, V O, Shlyakhovenko
Publikováno v:
Experimental oncology. 44(2)
To assess the inducible NO-synthase activity and the total RNase activity in tissue samples and blood neutrophils of the patients with prostate intraepithelial neoplasia (PIN) and prostate cancer (PCa) of different stages.NO level was measured in tum
Autor:
О А Samoylenko, V O Shlyakhovenko
Publikováno v:
Experimental oncology. 41(3)
Ribonucleases are enzymes that destroy RNA, play an important role in protein synthesis, epigenetic regulation of genetic activity, cell proliferation and apoptosis. Ribonucleases are important antimicrobial, antiviral and immune defense factors. Des
Autor:
V O Shlyakhovenko
Publikováno v:
Experimental Oncology. 38:2-8
In the review, the use of the ribonucleases for cancer therapy is discussed. Using of epigenetic mechanisms of regulation — blocking protein synthesis without affecting the DNA structure — is a promising direction in the therapy. The ribonuclease
Autor:
V O, Shlyakhovenko
Publikováno v:
Experimental oncology. 38(1)
In the review, the use of the ribonucleases for cancer therapy is discussed. Using of epigenetic mechanisms of regulation--blocking protein synthesis without affecting the DNA structure--is a promising direction in the therapy. The ribonucleases isol
Autor:
S P, Zaletok, L, Gulua, L, Wicker, V A, Shlyakhovenko, S, Gogol, O, Orlovsky, O V, Karnaushenko, A, Verbinenko, V, Milinevska, O, Samoylenko, I, Todor, T, Turmanidze
Publikováno v:
Experimental oncology. 37(4)
To evaluate antitumor effect of plant polyphenol extracts from green tea, red wine lees and/or lemon peel alone and in combination with antitumor drugs on the growth of different transplanted tumors in experimental animals.Green tea extract (GTE) was
Publikováno v:
Experimental oncology. 37(2)
To study the influence of polyamine metabolism inhibitors on the growth, metastasis and ornithine decarboxylase (ODC) activity of Lewis lung carcinoma.Experiments were performed on female mice C57Bl/6 with Lewis lung carcinoma. Nω-hydroxy-nor-argini
Publikováno v:
Experimental oncology. 36(2)
The present status of investigations about the anticancer activity which is inherent to medicinal mushrooms, as well as their biomedical potential and future prospects are discussed. Mushroom products and extracts possess promising immunomodulating a
Publikováno v:
Experimental oncology. 35(3)
To increase the effectiveness of anticancer vaccine delivery and activity via its immobilization on reconstructed chromatin (RC).The hybrid mice of CDF-1 line with transplanted P-388 leukemia were used. Reconstructed chromatin was obtained from the t
Autor:
V A, Shlyakhovenko
Publikováno v:
Experimental oncology. 31(3)
This review summarizes data on ambiguous biological functions of ribonucleases (RNases) at tumor growth. In some cases the raised level of enzyme activity in biological fluids can be regarded as an additional marker of malignant growth (pancreas canc
Autor:
L V, Garmanchouk, O N, Pyaskovskaya, Yu V, Yanish, V A, Shlyakhovenko, O I, Dasyukevich, G I, Solyanik
Publikováno v:
Experimental oncology. 27(4)
To evaluate the influence of new antitumor preparation BC1 produced on the base of Aconitum species on viability and electrokinetic properties of endothelial cells for estimation of mechanisms of its antitumor and antimetastatic activity.Cytotoxic/cy