Zobrazeno 1 - 10
of 18
pro vyhledávání: '"V. Tsikalov"'
Publikováno v:
Chemistry of Natural Compounds. 56:193-196
N-Acetylmuramyl-L-alanyl-D-isoglutamine α-phenylglycoside was synthesized from α-phenyl-D-glucosaminide peracetate, which was obtained by fusing β-D-glucosamine pentaacetate with phenol and zinc chloride followed by deacetylation. α-Phenyl-N-acet
Publikováno v:
Chemistry of Natural Compounds. 54:1139-1142
N-Acetylmuramyl-L-alanyl-D-isoglutamine α-cyclooctyl- and α-cyclopentadecylglycosides were synthesized. The starting peracetylated α-N-glucosaminides were synthesized by reacting the cycloalkanols with peracetyl α-D-glucosaminyl chloride in the p
Publikováno v:
Chemistry of Natural Compounds. 53:929-932
β-Cyclooctyl-, β-cyclodecyl-, and β-cyclopentadecylglycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine were prepared in yields of 39, 18, and 25%, respectively, (calculated for muramic acid) via the reaction of β-cycloalkyl-4,6-O-isopropylidene
Autor:
O. V. Kalyuzhin, M. V. Kiselevsky, E. L. Mulik, V. N. Tsikalova, A. E. Zemlyakov, V. V. Tsikalov, F. N. Kuzovlev, V. Ya. Chirva
Publikováno v:
Russian Journal of Bioorganic Chemistry. 34:103-109
Symmetric secondary linear alcohols were proposed as aglycones for the synthesis of lipophilic glycosides of β-N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP). Pentadecan-8-ol, nonadecan-10-ol, and tricosan-12-ol were glycosylated by the oxazoline met
Autor:
V. V. Tsikalov, O. V. Kalyuzhin, V. N. Tsikalova, E. L. Mulik, A. E. Zemlyakov, V. Ya. Chirva
Publikováno v:
Scopus-Elsevier
The following glycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) were synthesized: β-4-tert-butylcyclohexyl MDP, β-2-(adamant-1-yl)ethyl MDP, β-2,2-diphenylethyl MDP, and β-2-(p-biphenyl) ethyl MDP. The starting peracetylated β-N-acetyl
Publikováno v:
Russian Journal of Bioorganic Chemistry. 29:286-292
Hexyl, octyl, and cyclohexyl β-glycosides and heptyl and cyclohexyl α-glycosides of muramyl dipeptide (MDP) were synthesized. Tests in vitro and in vivo revealed lower immunostimulating activities of MDP α-glycosides in comparison with the corresp
Publikováno v:
Chemistry of Natural Compounds. 30:390-394
The synthesis has been effected of alkyl β-glycosides containing spacers with amino and carboxy groups at the end. As “prespacers” we used benzyl and 4-azidobutyl esters of 6-(L-alanyl-D-isoglutaminylamino)hexanoic acid. The use of the butyl and
Autor:
N M, Zholobak, N Ia, Spivak, A E, Zemliakov, V V, Tsikalov, T A, Chupakhina, V O, Kur'ianov, V Ia, Chirva
Publikováno v:
Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993). 69(4)
The uninvestigated interferon (IFN)-inducing capacity of glycoside derivatives of N-acetylmuramoyl-L-alanyl-D-isoglutamine (MDP) has been studied. Most MDP glycosides tested in vitro were more active than the reference preparation MDP. Under the in v
Publikováno v:
Bioorganicheskaia khimiia. 32(4)
Anomeric pairs of alpha- and beta-dodecyl, alpha- and beta-(1-pentylhexyl), and alpha- and beta-cyclododecyl glycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) were synthesized. The starting beta-D-glucosaminides were obtained by the oxazoli
Publikováno v:
Bioorganicheskaia khimiia. 31(6)
The following glycosides of N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) were synthesized: beta-4-tert-butylcyclohexyl MDP, beta-2-(adamant-1-yl)ethyl MDP, beta-2,2-diphenylethyl MDP, and 3-2-(p-biphenyl)ethyl MDP. The starting peracetylated beta-N-