Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage

Autor: Douglas Meyer, Jacob Kames, Haim Bar, Anton A. Komar, Aikaterini Alexaki, Juan Ibla, Ryan C. Hunt, Luis V. Santana-Quintero, Anton Golikov, Michael DiCuccio, Chava Kimchi-Sarfaty

Publikováno v: Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)

Abstract Background Gene expression is highly variable across tissues of multi-cellular organisms, influencing the codon usage of the tissue-specific transcriptome. Cancer disrupts the gene expression pattern of healthy tissue resulting in altered co

Externí odkaz: https://doaj.org/article/c7ca96719b204fc496ee0de68b57825b

Effect of genotype in the production and quality of sweet sorghum juice [Sorghum bicolor (L.) Moench]

Autor: M. Galicia-Juarez, V. Pecina-Quintero, Ma. E. Cisneros-López, G. Chavez-Villalba, M. Espinosa-Ramirez, María G. Álvarez- Ojeda, Carlos E. Aíl-Catzim

Publikováno v: Agro Productividad.

Objectives: To evaluate the production of juice and sugar, the physicochemical parameters of the juice during extraction and quantify the differences between genotypes. Design/Methodology/Approach: An experiment under irrigation was established with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::795da427c27b37daa1efc493d8aeddae
https://doi.org/10.32854/agrop.v15i7.2335

Codon and Codon-Pair Usage Tables (CoCoPUTs): Facilitating Genetic Variation Analyses and Recombinant Gene Design

Autor: Nobuko Hamasaki-Katagiri, Anton A. Komar, John C. Athey, Aikaterini Alexaki, Luis V. Santana-Quintero, Phuc Vihn Nguyen Lam, Jacob Kames, David D. Holcomb, Haim Bar, Ekaterina Osipova, Vahan Simonyan, Chava Kimchi-Sarfaty

Publikováno v: Journal of Molecular Biology. 431:2434-2441

Usage of sequential codon-pairs is non-random and unique to each species. Codon-pair bias is related to but clearly distinct from individual codon usage bias. Codon-pair bias is thought to affect translational fidelity and efficiency and is presumed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acb78faad7d118568501f42791fdbb9
https://doi.org/10.1016/j.jmb.2019.04.021

Response Prediction to Isocitrate Dehydrogenase (IDH) Inhibitors in Patients with IDH1- or IDH2-Mutated Acute Myeloid Leukemia Using Clinical and Genomic Data

Autor: Sean Smith, Emma C. Scott, Lorraine Pelosof, Richard Pazdur, Joseph Wynne, V. Ashutosh Rao, R. Angelo de Claro, Amy S. Rosenberg, Nora Holmes, Alexander J. Ambinder, Wenming Xiao, Kelly J. Norsworthy, Yong Zhang, Catherine Lai, Svetlana Petrovskaya, Luis V. Santana-Quintero, Julia A. Beaver, Gabriel Ghiaur, Michael Colgan, Colleen McGuire, Dickran Kazandjian, Kamil Kural

Publikováno v: Blood. 138:1285-1285

Background: Ivosidenib (Servier Pharmaceuticals LLC) and enasidenib (Celgene) are inhibitors of mutant IDH1 and IDH2, respectively, approved for the treatment of relapsed/refractory (R/R) AML with an IDH1 or IDH2 mutation (ivosidenib is also approved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ec47c98aa7ecd02efe559abbbc7f55f
https://doi.org/10.1182/blood-2021-147099

Properties of the Binary Neutron Star Merger GW170817

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Publikováno v: Phys.Rev.X
Phys.Rev.X, 2019, 9 (1), pp.011001. ⟨10.1103/PhysRevX.9.011001⟩
Physical Review X, 9(1):011001, 1-32. American Physical Society
American Physical Society
Physical Review X, 9, 1, pp. 1-32
Physical Review X
Physical Review X, 9, 1-32
Physical Review X, 9(1):011001. American Physical Society
LIGO Scientific Collaboration Virgo Collaboration Abbott, B. P. Aloy Toras, Miguel Angel Cerdá Durán, Pablo Cordero Carrión, Isabel Font Roda, José Antonio Marquina Vila, Antonio Obergaulinger, M. Sanchis Gual, Nicolas Torres Forné, Alejandro 2019 Properties of the Binary Neutron Star Merger GW170817 Physical Review X 9 1 011001-1 011001-32
RODERIC. Repositorio Institucional de la Universitat de Valéncia
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LIGO Scientific Collaboration and Virgo Collaboration 2019, ' Properties of the Binary Neutron Star Merger GW170817 ', Physical Review X, vol. 9, no. 1, 011001, pp. 1-32 . https://doi.org/10.1103/PhysRevX.9.011001
Physical Review X, Vol 9, Iss 1, p 011001 (2019)
Physical Review X, 9(1):11001. American Physical Society
The LIGO Scientific Collaboration, Virgo Collaboration, Harry, I W, Keitel, D, Lundgren, A P & Nuttall, L K 2019, ' Properties of the binary neutron star merger GW170817 ', Physical Review X, vol. 9, no. 1, 011001 . https://doi.org/10.1103/PhysRevX.9.011001
Physical Review X (2019), Nr. 1
PHYSICAL REVIEW X

On August 17, 2017, the Advanced LIGO and Advanced Virgo gravitational-wave detectors observed a low-mass compact binary inspiral. The initial sky localization of the source of the gravitational-wave signal, GW170817, allowed electromagnetic observat

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http://hdl.handle.net/10281/243036