Zobrazeno 1 - 10
of 14
pro vyhledávání: '"V Y, Kuperman"'
Publikováno v:
Physica Medica. 95:140-147
To evaluate the combined effect of heterogeneous target dose and heterogeneous radiosensitivity on tumor control probability (TCP) for different number of fractions (NThe linear-quadratic (LQ) model is employed to study dependence of TCP on NFormula
Autor:
V. Y. Kuperman, L. M. Lubich
Publikováno v:
Medical Physics. 47:5383-5391
PURPOSE To assess the role of reoxygenation of hypoxic tumor cells in hypofractionated radiotherapy of prostate cancer. METHODS The considered radiobiological model is based on the assumption of two populations (compartments) of cells: oxygenated (ae
Autor:
L M Lubich, V Y Kuperman
Publikováno v:
Physics in Medicine & Biology. 66:155006
Purpose.To evaluate how heterogeneity of the target dose and heterogeneity of intra-tumor radiosensitivity affect biologically effective dose (BED) and tumor control probability (TCP) depending on the number of fractions (Nf).Methods.The dependences
Autor:
W.-C. Lam, V. Y. Kuperman
Publikováno v:
Medical Physics. 33:1067-1073
The purpose of this study is to describe four new delivery schemes for intensity-modulated radiation therapy(IMRT). In the first two schemes the order in which segments are delivered is varied from fraction to fraction. The last two delivery schemes
Autor:
V Y, Kuperman
Publikováno v:
Medical physics. 40(8)
To investigate the effect of radiation protraction on biologically effective dose (BED) in the case when dose per fraction is significantly greater than the standard dose of 2 Gy.By using the modified linear-quadratic model with monoexponential repai
Autor:
V Y, Kuperman, G S, Spradlin
Publikováno v:
Medical physics. 38(12)
The aim of this study is to evaluate how simultaneously increasing fraction time and dose per fraction affect biologically effective dose for the target (BED(tar)) while biologically effective dose for the normal tissue (BED(nt)) is fixed.In this inv
Autor:
V Y, Kuperman
Publikováno v:
Medical physics. 35(11)
In the current study the author analyzes general properties of three different models used to predict normal tissue complications due to radiation: (1) Surviving fraction of normal cells in the framework of the linear quadratic (LQ) equation for cell
Publikováno v:
Physics in medicine and biology. 53(12)
The effect of radiation protraction in step-and-shoot IMRT is investigated for treatment plans created with the help of direct aperture optimization. The latter approach can be used during inverse planning for all clinical linear accelerators with co
Autor:
V Y, Kuperman, W C, Lam
Publikováno v:
Medical physics. 33(4)
The purpose of this study is to describe four new delivery schemes for intensity-modulated radiation therapy (IMRT). In the first two schemes the order in which segments are delivered is varied from fraction to fraction. The last two delivery schemes
Publikováno v:
Journal of magnetic resonance imaging : JMRI. 9(5)
With conventional Fourier transform (FT) magnetic resonance imaging (MRI), it is difficult to perform contrast-enhanced three-dimensional (3D) MR angiography (MRA) with the temporal and spatial resolution necessary to depict the carotid arteries. How