Zobrazeno 1 - 10
of 11
pro vyhledávání: '"V W Byrnes"'
Autor:
Jacob M. Hoffman, V V Sardana, Christine L. Schneider, Jill A. Wolfgang, V W Byrnes, Emilio A. Emini, Krishna K. Murthy, Elizabeth Roth, William A. Schleif, Anthony M. Smith, Karl M. Gelotte, K E Cobb
Publikováno v:
AIDS Research and Human Retroviruses. 10:107-110
Autor:
Emilio A. Emini, Jeffrey Douglas, Richard J. Whitley, George M. Shaw, John C. Kappes, Ferdinand E. Massari, William I. Lapidus, Michael S. Saag, Kevin W. Anderson, Oscar L. Laskin, Carol Hildebrand, V W Byrnes, William A. Schleif
Publikováno v:
New England Journal of Medicine. 329:1065-1072
Background The non-nucleoside reverse transcriptase inhibitors are novel antiretroviral agents with selective activity in vitro against human immunodeficiency virus type 1 (HIV-1). They act through direct inhibition of reverse transcriptase and are n
Autor:
W J Long, J A Wolfgang, Jon H. Condra, V V Sardana, A J Schlabach, C L Schneider, J A Waterbury, B S Wolanski, William A. Schleif, V W Byrnes
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:1576-1579
The nonnucleoside reverse transcriptase (RT) inhibitors comprise a class of structurally diverse compounds that are functionally related and specific for the human immunodeficiency virus type 1 RT. Viral variants resistant to these compounds arise re
Autor:
J A Waterbury, S. Staszewski, Joseph Kessler, D W Lineberger, Emilio A. Emini, V W Byrnes, F. E. Massari
Publikováno v:
Journal of Virology. 69:2637-2639
A quantitative assessment of human immunodeficiency virus type 1 turnover in patient cell-free virion and infected-cell compartments under the dynamic conditions imposed by an effective antiviral therapy was performed. The turnover was rapid, and fol
Autor:
W. Stille, J. L. Ryan, C. Kreisl, V W Byrnes, C. S. Hildebrand, William A. Schleif, S. Durr, F. E. Massari, V. I. Taylor, C L Schneider, H. von Briesen, Emilio A. Emini, S. Staszewski, Gary B. Calandra, R. Göhler, K. K. Bakshi, B. Hoffstedt, H. Rübsamen-Waigmann, K. W. Anderson, A. Kober, J. A. Waterbury
Publikováno v:
The Journal of infectious diseases. 171(5)
L-697,661 is a human immunodeficiency virus type 1 (HIV-1)-specific nonnucleoside reverse transcriptase (RT) inhibitor. Its tolerability and activity in combination with zidovudine were evaluated in a 48-week double-blind study. One hundred nineteen
Autor:
Donald J. Graham, J A Wolfgang, W J Long, Emilio A. Emini, L Gotlib, William A. Schleif, Jon H. Condra, C L Schneider, V W Byrnes, A J Schlabach
Publikováno v:
Antimicrobial agents and chemotherapy. 38(6)
To evaluate the potential that multiply resistant human immunodeficiency virus type 1 variants may arise during combination nucleoside and nonnucleoside reverse transcriptase inhibitor therapy, we constructed a series of mutant reverse transcriptase
Publikováno v:
Positive-Strand RNA Viruses ISBN: 9783211825228
The nonnucleoside reverse transcriptase (RT) inhibitors are structurally diverse compounds that are specific inhibitors of the human immunodeficiency virus type 1 RT enzyme. The compounds are largely functionally identical and bind to a common site i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1d23810acdc25c6acb36117813db04a
https://doi.org/10.1007/978-3-7091-9326-6_2
https://doi.org/10.1007/978-3-7091-9326-6_2
Publikováno v:
Archives of virology. Supplementum. 9
The nonnucleoside reverse transcriptase (RT) inhibitors are structurally diverse compounds that are specific inhibitors of the human immunodeficiency virus type 1 RT enzyme. The compounds are largely functionally identical and bind to a common site i
Autor:
T. L. Ruffing, M. E. Goldman, Jon H. Condra, Julie A. O'Brien, Jacob M. Hoffman, V W Byrnes, Emilio A. Emini, V V Sardana, William A. Schleif
Publikováno v:
Antimicrobial agents and chemotherapy. 37(5)
Pyridinone derivatives are potent and specific inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and HIV-1 replication in cell culture. However, the potential clinical usefulness of these compounds as monotherapeuti