Zobrazeno 1 - 10
of 12
pro vyhledávání: '"V W, MacDonald"'
Autor:
V. W. Macdonald, R. Motterlini
Publikováno v:
Artificial Cells, Blood Substitutes, and Biotechnology. 22:565-575
To study the mechanism by which cell-free hemoglobin preparations may alter coronary vascular reactivity, we investigated the effect of human hemoglobin cross-linked between alpha chains with bis(3,5-dibromosalicyl)fumarate (alpha alpha Hb) on the va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42081a22a66e03db553552bf8202c9e1
https://doi.org/10.3109/10731199409117885
https://doi.org/10.3109/10731199409117885
Autor:
J C, Hsia, D L, Song, S S, Er, L T, Wong, P E, Keipert, C L, Gomez, A, Gonzales, V W, Macdonald, J R, Hess, R M, Winslow
Publikováno v:
Biomaterials, Artificial Cells and Immobilization Biotechnology. 20:587-595
We have studied the plasma half-life (T 1/2), oxygen-binding affinity (P50), organ distribution, and excretion of the individual molecular weight (MW) components of human hemoglobin polymerized with periodate-oxidized, ring-opened raffinose (oR poly-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdc12468c6da45cb9f5bdee45dd6a81
https://doi.org/10.3109/10731199209119687
https://doi.org/10.3109/10731199209119687
Publikováno v:
Biomaterials, Artificial Cells and Artificial Organs. 18:263-282
Unpurified stroma-free hemoglobin (SFH) from water-lysed human red blood cells, hemoglobin Ao (HbAo), and hemoglobin cross-linked between alpha chains with 3,5-bis-dibromosalicyl-fumarate (HbXLDBBF) were infused into isolated perfused rabbit hearts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a786a1a70e954b73e24cd02f2bccfd
https://doi.org/10.3109/10731199009117306
https://doi.org/10.3109/10731199009117306
Autor:
R. R. Leslie-Holt, V. W. Macdonald
The role of the Armed Services Blood Program Office (ASBPO) is to ensure quality blood products are provided during peacetime and war. Delays occurring during shipment of products into the area of operation can have negative consequences on platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9a1122471d9757fcf5d9080be320707
https://doi.org/10.21236/ada442933
https://doi.org/10.21236/ada442933
Autor:
F J, Rentas, V W, Macdonald, S W, Rothwell, S J, McFaul, L V, Asher, A M, Kennedy, P J, Hmel, C J, Meledandri, J M, Salata, R W, Harman, T J, Reid
Publikováno v:
Transfusion. 44(7)
In late January 2003, some blood centers and hospitals throughout the US voluntarily sus-pended the use of some RBC and plasma units for trans-fusion due to the presence of unknown white particulate matter (WPM) in these units. To better understand t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02e81cc6f05ef560450b63b3f65b02af
https://pubmed.ncbi.nlm.nih.gov/15225232
https://pubmed.ncbi.nlm.nih.gov/15225232
Publikováno v:
Biochimica et biophysica acta. 1495(2)
We investigated the toxicity of hemoglobin/myoglobin on endothelial cells under oxidative stress conditions that include cellular hypoxia and reduced antioxidant capacity. Bovine aorta endothelial cells (BAECs), grown on microcarrier beads, were subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b07784b93438d2b704ebeae15d3a6e7
https://pubmed.ncbi.nlm.nih.gov/10656972
https://pubmed.ncbi.nlm.nih.gov/10656972
Publikováno v:
The Journal of laboratory and clinical medicine. 123(5)
This report describes the tissue distribution and long-term (14-day) excretion of hemoglobin cross-linked between the alpha-chains (alpha alpha Hb) with carbon 14-labeled bis(3,5-dibromosalicyl)fumarate. Fully conscious, chronically cannulated rats (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c783ca291242e6530f23b05a15abbc6
https://pubmed.ncbi.nlm.nih.gov/8195676
https://pubmed.ncbi.nlm.nih.gov/8195676
Autor:
V. W. Macdonald, R. Motterlini
Publikováno v:
ResearcherID
Cell-free hemoglobin (Hb) preparations have been shown to alter vascular tone in vitro and in vivo. The high affinity of Hb for nitric oxide, the putative endothelium-derived relaxing factor (EDRF), may be primarily responsible for this activity, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726de19fbf836a789bfd7bd8e214139c
https://pubmed.ncbi.nlm.nih.gov/7508430
https://pubmed.ncbi.nlm.nih.gov/7508430
Autor:
V W MacDonald, F F Jöbsis
Publikováno v:
The Journal of General Physiology
The spectral characteristics of the pH-sensitive dyes neutral red (NR) and bromcresol purple (BCP) were utilized for studies of the changing intracellular pH (pHi) of sartorius muscles from Rana pipiens, both during the course of an isometric twitch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c7feb366dd37b489ff10618ee0a00b
http://europepmc.org/articles/PMC2228422
http://europepmc.org/articles/PMC2228422
Publikováno v:
The Journal of laboratory and clinical medicine. 105(1)
Severe iron deficiency anemia in rats causes a decrease in the activities of iron-containing enzymes in skeletal muscle mitochondria, and subsequent diminished respiratory activity has been linked to lowered work capacity. It was suggested that loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b45401ba1572d5d518cc715dd23174c1
https://pubmed.ncbi.nlm.nih.gov/2981941
https://pubmed.ncbi.nlm.nih.gov/2981941