Výsledky vyhledávání - "V V Ogurtsov"

Akademický článek

Synthesis and primary screening of the antioxidant activity of some 4-thioxo- and 4-imino- thiazolidin-2-ones

Autor: Z. І. Сhulovska, І. V. Drapak, T. I. Chaban, V. S. Matiychuk, I. G. Chaban, V. V. Ogurtsov

Publikováno v: Фармацевтичний журнал, Vol 1, Pp 17-25 (2021)

As a result of metabolic transformations of substances in the human body in the reactions of lipid peroxidation, reactive oxygen species are formed. Normally, the regulation of the production of activated oxygen metabolites and free radicals in human

Externí odkaz: https://doaj.org/article/1cf91c6d8d734d81afce7f72454489e5

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Akademický článek

Development of effective anti-inflammatory drug candidates among novel thiazolopyridines

Autor: T. I. Chaban, V. S. Matiychuk, V. V. Ogurtsov, I. G. Chaban, I. A. Nektegayev

Publikováno v: The Ukrainian Biochemical Journal, Vol 92, Iss 2, Pp 132-139 (2020)

In an effort to develop novel anti-inflammatory agents, a series of thiazolo[4,5-b]pyridines were synthesized and modified at the N3 position. The structures of the obtained compounds were confirmed by 1H NMR spectroscopy and elemental analysis. The

Externí odkaz: https://doaj.org/article/242d7b3868fa42f2835fa3987cd0e259

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Synthesis, Anti-Inflammatory Properties and Molecular Docking of 2-(5-Aryltetrazol-2-yl)-and 2-(1H-Tetrazol-5-ylsulphanyl)-N-Thiazol-2-ylacetamides

Autor: V. T. Foliush, V. V. Ogurtsov, T. I. Chaban, Vasyl S. Matiychuk

Publikováno v: Russian Journal of Bioorganic Chemistry. 47:889-895

By the reaction of chloroacetamidothiazole with 5-aryltetrazoles and 5-mercaptotetrazoles 2-(5-aryltetrazol-2-yl)- and 2-(1H-tetrazol-5-ylsulfanyl)-N-thiazol-2-ylacetamides were prepared. The study of the anti-inflammatory properties of the synthesiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c54a34155fb0bd673915f0071979986
https://doi.org/10.1134/s1068162021040051

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СИНТЕЗ ТА ДОСЛІДЖЕННЯ АНТИМІКРОБНОЇ АКТИВНОСТІ ДЕЯКИХ ПІРАЗОЛЗАМІЩЕНИХ 7H-[1,2,4]ТРИАЗОЛО[3,4-B][1,3,4]ТІАДІАЗИНІВ

Autor: Vasyl S. Matiychuk, Iryna Myrko, V. V. Ogurtsov, T. I. Chaban

Publikováno v: Фармацевтичний часопис. :5-13

Мета роботи. Здійснити синтез деяких нових піразолзаміщених 7H-[1,2,4]триазоло[3,4-b][1,3,4]тіадіазинів та провести дослідження антимікробних в�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f87c9bf84bade1c9f17e83677ac3779
https://doi.org/10.11603/2312-0967.2021.1.11986

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Synthesis, Molecular Docking and Biological Properties of Novel Thiazolo[4,5-b]pyridine Derivatives

Autor: Y. E. Matiichuk, Olga Ya. Shyyka, I. G. Chaban, T. I. Chaban, Vasyl S. Matiychuk, Ihor Nektegayev, V. V. Ogurtsov

Publikováno v: Acta Chimica Slovenica, Vol 67, Iss 4, Pp 1035-1043 (2020)

The synthesis, anti-inflammatory and antioxidant properties of novel 5-hydroxy-7-methyl-3H-thiazolo[4,5-b]pyridin-2-one derivatives were discussed. Fused thiazolo[4,5-b]pyridin-2-ones were synthesized and modified at the N3, C5 and C6 positions of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15617c3d85fbc8d30180e54e279650d9
https://doi.org/10.17344/acsi.2019.5439

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Anti-inflammatory properties of some novel thiazolo[4,5-b]pyridin-2-ones

Autor: Olexandra Komarytsya, Ihor Nektegaev, Vasyl S. Matiychuk, Iryna Myrko, T. I. Chaban, I. G. Chaban, V. V. Ogurtsov

Publikováno v: Pharmacia 67(3): 121-127

Synthesis of novel N3 and C5 substituted thiazolo[4,5-b]pyridin-2-ones was carried out on the basis of [3+3]-cyclocodensation, acylation and alkylation reactions. The structures of the obtained compounds were confirmed by 1H NMR spectroscopy, and ele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d346523255d6b9b13fd78a3d2ec63a
https://doi.org/10.3897/pharmacia.67.e38969

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