Výsledky vyhledávání

Construction of a generalized consensus matrix for recognition of vertebrate pre-mRNA 3'-terminal processing sites

Autor: V. V. Shamin, Nikolay A. Kolchanov, Yury V. Kondrakhin

Publikováno v: Computer applications in the biosciences : CABIOS. 10(6)

Using a set of sequences of 63 cleavage/polyadenylation sites of vertebrate pre-mRNA, a generalized consensus matrix was constructed. The elements of the matrix were the absolute frequencies of oligonucleotides of length l at the ith position of site

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b6cdc88e58e109e76a31c5c94ffb6ff
https://pubmed.ncbi.nlm.nih.gov/7704658

Zobrazit plný text záznamu

[Design of the generalized consensus matrix for recognizing sites of 3'-terminal processing of vertebrate pre-mRNA]

Autor: Iu V, Kondrakhin, V V, Shamin

Publikováno v: Molekuliarnaia biologiia. 28(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9df25bba1822a1de673ea5d24be3fe5a
https://pubmed.ncbi.nlm.nih.gov/8052244

Zobrazit plný text záznamu

[Design of four-helix protein--a possible vaccine against human immunodeficiency virus (HIV-1)]

Autor: A M, Eroshkin, P A, Zhilkin, V V, Shamin

Publikováno v: Molekuliarnaia biologiia. 27(3)

Successful approach to the development of safe and effective synthetic vaccines requires that different B- and T-cell epitopes of the infectious agent be included into the vaccine construction. It is suggested that vaccines should be constructed as p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::000a21b63c1785b7e955e92d51e433a8
https://pubmed.ncbi.nlm.nih.gov/7686249

Zobrazit plný text záznamu

[Model polycistron operon for studying conjugated translation in E. coli cells. The role of a stream of ribosomes]

Autor: V V, Kravchenko, V V, Shamin, I P, Gileva, V A, Likhoshvaĭ, S K, Korzhenevskiĭ, V N, Dobrynin, S A, Filippov, S A, Chuvpilo, V G, Korobko

Publikováno v: Bioorganicheskaia khimiia. 16(12)

The role of "stream" of ribosomes upon translation of polycistronic mRNAs has been studied using an artificial polycistron. It has been found that the levels of activation of cistron Ci + 1 out of two adjacent cistrons (Ci and Ci + 1) depends, in add

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e3685e4ae1417db0f0cdb2c26fe65fda
https://pubmed.ncbi.nlm.nih.gov/2128600

Zobrazit plný text záznamu

[Formation and properties of artificial polycistrons containing truncated genes for E. coli tryptophan operon and phage M13 envelope protein]

Autor: V V, Kravchenko, I P, Gileva, V V, Shamin, V A, Kulichkov, V N, Dobrynin

Publikováno v: Bioorganicheskaia khimiia. 13(9)

Using gene fragments encoding the leader peptide of E. coli tryptophane operon (as duplicated fragment HhaI-140) or M13 phage coat protein (as TaqI-381 or HaeIII-1623 fragments) and basing on pDS1 family of plasmids, expression vectors have been cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b2c325a9209730af3531e1d46c44bffb
https://pubmed.ncbi.nlm.nih.gov/3322290

Zobrazit plný text záznamu

[Duplication of a synthetic gene for human leukocyte interferon and its expression in polycistron mRNA with coupled translation system]

Autor: V V, Kravchenko, I P, Gileva, V V, Shamin, V A, Kulichkov, V N, Dobrynin

Publikováno v: Bioorganicheskaia khimiia. 13(9)

Using a chemically synthesised adapter, the coding part of an artificial gene for human leukocyte alpha 2 interferon (ifn-alpha 2) has been duplicated. The adapter contained a termination signal of the first gene (TAA) within the Shine-Dalgarno seque

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91d19e4e2d134785885b0ffae19082a4
https://pubmed.ncbi.nlm.nih.gov/3322291

Zobrazit plný text záznamu

[Effect of alternative secondary structures on the effectiveness of translation of polycistron mRNA]

Autor: V V, Kravchenko, V V, Shamin, I P, Gileva, V A, Likhoshvaĭ, V N, Dobrynin

Publikováno v: Doklady Akademii nauk SSSR. 301(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cccec3422acf0c2fdb083b1f74b32513
https://pubmed.ncbi.nlm.nih.gov/3056680

Zobrazit plný text záznamu

[Mechanism of regulation of polycistron mRNA. The role of mutual position of cistrons]

Autor: V V, Kravchenko, V V, Shamin, I P, Gileva, V A, Likhoshvaĭ, V A, Kulichkov

Publikováno v: Doklady Akademii nauk SSSR. 295(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d97a396ac8eeb998a09af3b181f63e67
https://pubmed.ncbi.nlm.nih.gov/2441945

Zobrazit plný text záznamu

[Effectiveness of distal gene translation in polycistrons depends upon the arrangement of regulatory signals on a template]

Autor: V V, Kravchenko, V V, Shamin, I P, Gileva, V A, Likhoshvaĭ, V N, Dobrynin

Publikováno v: Bioorganicheskaia khimiia. 14(10)

The role of the translational terminator and initiator signals arrangement for two adjacent genes in polycistronic mRNA has been studied. Semisynthetic beta-galactosidase gene (lacZ) of E. coli and fragment of phage M13 DNA (with promoter PVIII, gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28b6bb5a0f301836076919b8b2ae1bb2
https://pubmed.ncbi.nlm.nih.gov/3233097

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání