Zobrazeno 1 - 10
of 39
pro vyhledávání: '"V V, Gurevich"'
Autor:
E V, Gurevich, V V, Gurevich
Publikováno v:
British journal of pharmacology. 172(13)
Traditional pharmacology is defined as the science that deals with drugs and their actions. While small molecule drugs have clear advantages, there are many cases where they have proved to be ineffective, prone to unacceptable side effects, or where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87b05ce4b6833ec925d0b2c393c61b18
https://pubmed.ncbi.nlm.nih.gov/25572005
https://pubmed.ncbi.nlm.nih.gov/25572005
Publikováno v:
Handbook of experimental pharmacology. (186)
Arrestins are versatile regulators of cellular signaling expressed in every cell in the body. Arrestins bind active phosphorylated forms of their cognate G-protein-coupled receptors, shutting down G-protein activation and linking receptors to alterna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::01d9d5799c1a798880d8faa9c8b3a991
https://pubmed.ncbi.nlm.nih.gov/18491047
https://pubmed.ncbi.nlm.nih.gov/18491047
Publikováno v:
The Journal of biological chemistry. 275(52)
Arrestins quench the signaling of a wide variety of G protein-coupled receptors by virtue of high-affinity binding to phosphorylated activated receptors. The high selectivity of arrestins for this particular functional form of receptor ensures their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de7436a029223112e06467c6b5eb69c2
https://pubmed.ncbi.nlm.nih.gov/11024026
https://pubmed.ncbi.nlm.nih.gov/11024026
Autor:
W C, Smith, E V, Gurevich, D R, Dugger, S A, Vishnivetskiy, C L, Shelamer, J H, McDowell, V V, Gurevich
Publikováno v:
Investigative ophthalmologyvisual science. 41(9)
To clone, localize, and determine functional binding characteristics of rod and cone arrestins from the retina of the tiger salamander (Ambystoma tigrinum).Two arrestins from salamander retina were cloned on the basis of their homology to known arres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d870c3b42e3691102137239c0cfe155
https://pubmed.ncbi.nlm.nih.gov/10937552
https://pubmed.ncbi.nlm.nih.gov/10937552
Autor:
V V, Gurevich, J L, Benovic
Publikováno v:
Methods in enzymology. 315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f912e134cc68d124993ac419c1de36a1
https://pubmed.ncbi.nlm.nih.gov/10736718
https://pubmed.ncbi.nlm.nih.gov/10736718
Publikováno v:
Cell. 97(2)
G protein-coupled signaling is utilized by a wide variety of eukaryotes for communicating information from the extracellular environment. Signal termination is achieved by the action of the arrestins, which bind to activated, phosphorylated G protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fcff5ce8f58cf4131b714df4f111ccf
https://pubmed.ncbi.nlm.nih.gov/10219246
https://pubmed.ncbi.nlm.nih.gov/10219246
Autor:
O B, Goodman, J G, Krupnick, F, Santini, V V, Gurevich, R B, Penn, A W, Gagnon, J H, Keen, J L, Benovic
Publikováno v:
Advances in pharmacology (San Diego, Calif.). 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f35619984ffd58f6d5b9b820e4e02bf5
https://pubmed.ncbi.nlm.nih.gov/9327931
https://pubmed.ncbi.nlm.nih.gov/9327931
Publikováno v:
The Journal of biological chemistry. 272(38)
Recent studies have identified agonist-dependent phosphorylation as a critical event in the rapid uncoupling of the m2 muscarinic cholinergic receptors (mAChR) from G-proteins and sequestration of the receptors away from the cell surface. However, mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8262479cc576842b5fee5b7751c9de66
https://pubmed.ncbi.nlm.nih.gov/9295310
https://pubmed.ncbi.nlm.nih.gov/9295310
Publikováno v:
The Journal of biological chemistry. 272(29)
Quenching of phototransduction in retinal rod cells involves phosphorylation of photoactivated rhodopsin by the enzyme rhodopsin kinase followed by binding of the protein arrestin. Although it has been proposed that the mechanism of arrestin quenchin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::354fa338cfacbfaee6aa26ea51bf9057
https://pubmed.ncbi.nlm.nih.gov/9218446
https://pubmed.ncbi.nlm.nih.gov/9218446
Publikováno v:
The Journal of biological chemistry. 272(23)
Previously we demonstrated that nonvisual arrestins exhibit a high affinity interaction with clathrin, consistent with an adaptor function in the internalization of G protein-coupled receptors (Goodman, O. B., Jr., Krupnick, J. G., Santini, F., Gurev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::585e569af5242cf2a54a627c61cf566c
https://pubmed.ncbi.nlm.nih.gov/9169477
https://pubmed.ncbi.nlm.nih.gov/9169477