Výsledky vyhledávání - "V V, Firstova"

Akademický článek

Identification of Immunological Correlates of Protection during Development of Specific Immunity to Francisella tularensis

Autor: A. S. Kartseva, M. V. Silkina, T. A. Ivashchenko, Ya. O. Romanenko, L. V. Sayapina, V. V. Firstova

Publikováno v: Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 15-24 (2024)

Live tularemia vaccine is one of the most effective bacterial vaccines. However, it also has high residual virulence for laboratory animals and may cause adverse reactions in individuals with compromised immune systems. The development of a safe and

Externí odkaz: https://doaj.org/article/34c531eb01724a0a8c30342d0651fc5b

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Akademický článek

Monoclonal Antibodies Capable of Inhibiting the Interaction of the Receptor Binding Domain of SARS-CoV-2 Virus with the Angiotensin-Converting Receptor 2 of Human Cells

Autor: T. A. Ivashchenko, Ya. O. Romanenko, A. S. Kartseva, M. V. Silkina, M. A. Mar’in, A. E. Khlyntseva, N. A. Zeninskaya, I. G. Shemyakin, V. V. Firstova

Publikováno v: Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 111-117 (2024)

The aim of the work was to evaluate the ability of monoclonal antibodies to inhibit the interaction of the receptor binding domain (RBD) in S protein of SARS-CoV-2 virus variants, Wuhan-Hu-1 and BQ 1.1, with the angiotensin-converting receptor 2 (ACE

Externí odkaz: https://doaj.org/article/47abd4b9f6f641cf80ab4fc14a4f8dcd

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Akademický článek

Humoral immune response to shiga toxin 2 (Stx2) in children with escherichiosis with hemolytic-uremic syndrome

Autor: Maria A. Shkuratova, A. E. Khlyntseva, O. V. Kalmantaeva, N. N. Kartsev, A. L. Muzurov, V. V. Firstova

Publikováno v: Инфекция и иммунитет, Vol 14, Iss 3, Pp 557-563 (2024)

Shiga toxin-producing Escherichia coli (STEC) causes acute intestinal infections and also causes acute renal failure, especially in children. Shiga toxins (Stx) occupy a central place in the pathogenesis of hemolytic uremic syndrome (HUS) in Escheric

Externí odkaz: https://doaj.org/article/504479433d4a4b209a03a3e4744ee44f

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Akademický článek

Evaluation of the long-term memory T cell in mice after immunization with a live tularemia vaccine

Autor: A. S. Kartseva, M. V. Silkina, G. M. Titareva, T. I. Kombarova, R. I. Mironova, V. V. Firstova

Publikováno v: Медицинская иммунология, Vol 25, Iss 3, Pp 673-678 (2023)

The vaccine strain F. tularensis 15 NIIEG induces long-lived cell-mediated immunity but exhibits a certain reactogenicity and genetic instability. Progress in development of a vaccine against tularemia has been limited by a lack of information regard

Externí odkaz: https://doaj.org/article/d3438754f4644d6c8b6e2fb301782238

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Akademický článek

Characterization of Immunogenic and Protective Properties of the Modified Variants of the Strain Francisella tularensis 15 NIIEG

Autor: A. S. Kartseva, O. V. Kalmantaeva, M. V. Silkina, T. I. Kombarova, V. M. Pavlov, A. N. Mokrievich, V. V. Firstova

Publikováno v: Проблемы особо опасных инфекций, Vol 0, Iss 3, Pp 62-69 (2020)

Francisella tularensis is an intracellular bacterium that causes tularemia. Progress in creating a safe and effective vaccine for the prevention of tularemia is challenging due to a lack of knowledge about immunological parameters indicative of prote

Externí odkaz: https://doaj.org/article/79a4472219244325836fcac8859e2970

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Akademický článek

Current understanding of Bacillus anthracis toxin molecules organization and approaches for blocking their cytotoxic action

Autor: V. V. Firstova, I. G. Shemyakin, I. A. Dyatlov

Publikováno v: Инфекция и иммунитет, Vol 9, Iss 5-6, Pp 639-647 (2020)

Here, we review the data on mechanisms inhibiting cytotoxic effect of anthrax toxin on the immune system cells. Various disease forms, immunopathogenesis and contemporary methods for anthrax treatment are discussed. In addition, an anthrax toxin was

Externí odkaz: https://doaj.org/article/4a376f50f66641bb8895bee6f747be03

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Akademický článek

Detecting specific memory t and b cells in volunteers annually revaccinated with live anthrax vaccine

Autor: V. V. Firstova, A. S. Kartseva, M. V. Silkina, M. A. Marin, Ia. O. Muntian, A. K. Ryabko, I. G. Shemyakin

Publikováno v: Инфекция и иммунитет, Vol 9, Iss 3-4, Pp 495-503 (2019)

Currently, live anthrax vaccine has been used for vaccine prophylaxis in Russia and neighbor countries for seve ral decades, but precise mechanism of post-vaccination protection mechanism remains unclear. Here, we provide data on examining serum anti

Externí odkaz: https://doaj.org/article/2f65465c0b2849d3b5eff8ad2193e61e

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