Zobrazeno 1 - 10
of 17
pro vyhledávání: '"V V, Bychko"'
Autor:
A. V. Kravchenko, E. A. Orlova-Morozova, T. E. Shimonova, O. A. Kozyrev, F. I. Nagimova, N. G. Zaharova, E. S. Ivanova, U. A. Kuimova, A. A. Popova, O. E. Chernova, O. S. Tonkih, D. A. Gusev, A. A. Yakovlev, V. V. Pokrovsky, V. V. Bychko, N. V. Vostokova
Publikováno v:
Журнал инфектологии, Vol 10, Iss 2, Pp 76-82 (2018)
A randomized multicenter 96-week study of an elsulfavirine (ESV), non-nucleoside reverse transcriptase inhibitor (NNRTI) of novel generation, in combination with 2 nucleoside/ nucleotide reverse transcriptase inhibitors (NRTIs) was conducted in naive
Externí odkaz:
https://doaj.org/article/ccd16d06c41c4c1cac7a9639593806e6
Autor:
Ya. A. Ivanenkov, Pavel M. Yamanushkin, V. M. Kisil, A. V. Ivashchenko, Ilya Okun, Andrey Alexandrovich Ivashchenko, Oleg D. Mitkin, O. M. Korzinov, V. Yu. Vedenskii, Elena A. Bulanova, I. A. Leneva, V. V. Bychko
Publikováno v:
Pharmaceutical Chemistry Journal. 48:569-581
New substituted ethyl esters of 2,4-bis-aminomethyl-5-hydroxy-1H-indole-3-carboxylic acids, 8-aminomethyl-2-methyl-2,3-dihydro-1H,7H-[1,3]-oxazino-[5,6-e]indole-9-carboxylic acids, and members of the previously unknown 4,5-dihydro-1H-pyrrolo[4,3,2-de
Autor:
V. V. Bychko, O. M. Korzinov, Oleg D. Mitkin, V. Yu. Vedenskii, Elena A. Bulanova, Ilya Okun, I. A. Leneva, V. M. Kisil, Pavel M. Yamanushkin, A. V. Ivashchenko
Publikováno v:
Pharmaceutical Chemistry Journal. 47:636-650
New substituted ethyl 5-hydroxy-1,2-dimethyl-1H-indole-3-carboxylates and 7,8-dimethyl-1,2,3,7-tetrahydro[1,3]oxazino[5,6-e]indole-9-carboxylates including arbidol analogs in addition to 6-hydroxy-1-methyl-7-pyridin-3-yl-4,5-dihydropyrrolo[4,3,2-de]i
Autor:
A V, Ivashchenko, P M, Iamanushkin, O D, Mit'kin, E V, Ezhova, O M, Korzinov, N A, Shevkun, R N, Karapetian, V V, Bychko, A A, Ivashchenko, V Z, Agrba, B A, Lapin, S V, Orlov, I É, Kuznetsov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 77(12)
Pharmacological safety of a new type of HCV inhibitor, AV0012, was studied including acute, subchronic and chronic toxicity in mice, rats and monkeys. Genotoxicity was assessed using the Ames test and the chromosomal aberrations assay in the bone mar
Autor:
A V, Ivashchenko, P M, Iamanushkin, O D, Mit'kin, E V, Ezhova, O M, Korzinov, E A, Bulanova, A G, Koriakova, P V, Vyshemirskaia, V V, Bychko, A A, Ivashchenko
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 77(10)
Several novel compounds were found to be potent inhibitors of the HCV (JFH-1 isolate) infection in vitro. Human serum did not significantly reduce antiviral activity of the lead compound, AVR560 (4-fold). The immunohistochemistry studies with the Huh
Autor:
A V, Ivashchenko, P M, Iamanushkin, O D, Mit'kin, E V, Ezhova, O M, Korzinov, N A, Shevkun, A G, Koriakova, R N, Karapetian, V V, Bychko, A A, Ivashchenko, V Z, Agrba, B A, Lapin, S V, Orlov
Publikováno v:
Eksperimental'naia i klinicheskaia farmakologiia. 77(4)
In vitro immunohistochemical investigations on the human hepatoma cell line (Huh7) infected with hepatitis C virus (HCV) strain JFH-1 showed that AV0012 compound blocks the early stages of viral infection. AV0012 also blocked viral infection spread i
Autor:
M A, Bundule, V V, Bychko, Iu B, Saulitis, E E, Liepin'sh, G P, Borisova, I A, Petrovskiĭ, V V, Tsibinogin, P P, Pumpen, E Ia, Gren
Publikováno v:
Doklady Akademii nauk SSSR. 312(4)
Publikováno v:
Doklady Akademii nauk SSSR. 274(5)
Publikováno v:
Bioorganicheskaia khimiia. 12(3)
The nucleotide sequence of the 3'-terminal region of the cloned bovine leukaemia virus cDNA (1474 bp) was elucidated using both Sanger and Maxam-Gilbert techniques. This DNA region contains U3 and R parts of the BLV LTR and an upstream sequence with
Publikováno v:
Molekuliarnaia biologiia. 15(5)
A series of plasmids with tetracycline resistance genes (Tcr-operon) subjected to transcription from chloramphenicol acetyl transferase promoter (Cmr-promoter) have been constructed on the basis of plasmid pBR325, AprCmrTcr. For this purpose, a 0.8 M