Zobrazeno 1 - 10
of 373
pro vyhledávání: '"V Tse"'
Publikováno v:
Continence, Vol 2, Iss , Pp 1- (2022)
Externí odkaz:
https://doaj.org/article/4058bbe09f4b4a80ad2806cdb27568d1
Autor:
Rita M. Meganck, Caitlin E. Edwards, Michael L. Mallory, Rhianna E. Lee, Hong Dang, Alexis B. Bailey, Jason A. Wykoff, Samuel C. Gallant, Deanna R. Zhu, Boyd L. Yount, Takafumi Kato, Kendall M. Shaffer, Satoko Nakano, Anne Marie Cawley, Vishwaraj Sontake, Jeremy R. Wang, Robert S. Hagan, Melissa B. Miller, Purushothama Rao Tata, Scott H. Randell, Longping V. Tse, Camille Ehre, Kenichi Okuda, Richard C. Boucher, Ralph S. Baric
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114076- (2024)
Summary: The severe acute respiratory syndrome coronavirus 2 pandemic is characterized by the emergence of novel variants of concern (VOCs) that replace ancestral strains. Here, we dissect the complex selective pressures by evaluating variant fitness
Externí odkaz:
https://doaj.org/article/f8f7061e966c4c31ad0d17d536355449
Autor:
Ellen Young, Boyd Yount, Petraleigh Pantoja, Sandra Henein, Rita M. Meganck, Jennifer McBride, Jennifer E. Munt, Thomas J. Baric, Deanna Zhu, Trevor Scobey, Stephanie Dong, Longping V. Tse, Melween I. Martinez, Armando G. Burgos, Rachel L. Graham, Laura White, Aravinda DeSilva, Carlos A. Sariol, Ralph S. Baric
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Here, the authors report a live chimeric DENV2/4 EDII virus, encoding DENV2 and DENV4 neutralizing epitopes, that replicates efficiently in primates and simultaneously elicits neutralizing DENV2 and DENV4 type-specific antibodies, providing domain-sp
Externí odkaz:
https://doaj.org/article/6da0934f0e114ea8bd63f572e1f9e010
Autor:
Rita M Meganck, Deanna Zhu, Stephanie Dong, Lisa J Snoderly-Foster, Yago R Dalben, Devina Thiono, Laura J White, Arivianda M DeSilva, Ralph S Baric, Longping V Tse
Publikováno v:
eLife, Vol 12 (2023)
A hallmark of dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://doaj.org/article/052e2b8492e2439d954641c9e43adbfa
Autor:
Matthew R. Chang, Luke Tomasovic, Natalia A. Kuzmina, Adam J. Ronk, Patrick O. Byrne, Rebecca Johnson, Nadia Storm, Eduardo Olmedillas, Yixuan J. Hou, Alexandra Schäfer, Sarah R. Leist, Longping V. Tse, Hanzhong Ke, Christian Coherd, Katrina Nguyen, Maliwan Kamkaew, Anna Honko, Quan Zhu, Galit Alter, Erica Ollmann Saphire, Jason S. McLellan, Anthony Griffiths, Ralph S. Baric, Alexander Bukreyev, Wayne A. Marasco
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
COVID-19 can be treated with monoclonal antibodies against SARS-CoV-2, but emerging new variants might show resistance towards existing therapy. Here authors show that anti-SARS-CoV-2 spike human single-chain antibody fragments could gain neutralizin
Externí odkaz:
https://doaj.org/article/d418ec52ee6b432581629e7a51ee58b4
Autor:
Longping V. Tse, Rita M. Meganck, Stephanie Dong, Lily E. Adams, Laura J. White, Michael L. Mallory, Ramesh Jadi, Aravinda M. de Silva, Ralph S. Baric
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Maturation of dengue viruses (DENVs) alters the structure, immunity, and infectivity of the virion and highly mature particles represent the dominant form in vivo. The production of highly mature virions principally relies on the structure a
Externí odkaz:
https://doaj.org/article/60abca8488114aa194c89a1d68e2e9f3
Autor:
Ana C. Puhl, Ethan J. Fritch, Thomas R. Lane, Longping V. Tse, Boyd L. Yount, Carolina Q. Sacramento, Natalia Fintelman-Rodrigues, Tatyana Almeida Tavella, Fabio Trindade Maranhão Costa, Stuart Weston, James Logue, Matthew Frieman, Lakshmanane Premkumar, Kenneth H. Pearce, Brett L. Hurst, Carolina Horta Andrade, James A. Levi, Nicole J. Johnson, Samantha C. Kisthardt, Frank Scholle, Thiago Moreno L. Souza, Nathaniel John Moorman, Ralph S. Baric, Peter B. Madrid, Sean Ekins
Publikováno v:
ACS Omega, Vol 6, Iss 11, Pp 7454-7468 (2021)
Externí odkaz:
https://doaj.org/article/f5c5fda4ba7d411a9be4f5d7993c395f
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Emerging coronaviruses (CoV) are constant global public health threats to society. Multiple ongoing clinical trials for vaccines and antivirals against CoVs showcase the availability of medical interventions to both prevent and treat the future emerg
Externí odkaz:
https://doaj.org/article/fb10e439aeef47708bec3eaead6dddc7
Autor:
Victoria J Madigan, Julianne A Yuziuk, Anna M Chiarella, Tyne O Tyson, Rita M Meganck, Zachary C Elmore, Longping V Tse, Nathaniel A Hathaway, Aravind Asokan
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007988 (2019)
Adeno-associated viruses (AAV) are Dependoparvoviruses that have shown promise as recombinant vectors for gene therapy. While infectious pathways of AAV are well studied, gaps remain in our understanding of host factors affecting vector genome expres
Externí odkaz:
https://doaj.org/article/fc7fbedd06ca440da188d4b61628143e
Autor:
Rita M. Meganck, Deanna Zhu, Stephanie Dong, Lisa J. Snoderly-Foster, Yago R. Dalben, Devina Thiono, Laura J. White, Aravinda M. DeSilva, Ralph S. Baric, Longping V. Tse
Publikováno v:
bioRxiv
A hallmark of Dengue virus (DENV) pathogenesis is the potential for antibody-dependent enhancement, which is associated with deadly DENV secondary infection, complicates the identification of correlates of protection, and negatively impacts the safet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ed5d83705e9b49ba9f8de7f86938f1
https://europepmc.org/articles/PMC10081285/
https://europepmc.org/articles/PMC10081285/