Zobrazeno 1 - 10
of 446
pro vyhledávání: '"V Swanson"'
Autor:
Mushtaq Ahmed, Eric Farris, Rosemary V. Swanson, Shibali Das, Yan Yang, Tyler Martin, Shabaana A. Khader
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTTuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis (Mtb), affects the lungs of infected individuals (pulmonary TB) but can also affect other sites (extrapulmonary TB). The only licensed vaccine Mycobacterium bo
Externí odkaz:
https://doaj.org/article/b8b785f8090d483bb14fe5784170183b
Autor:
Molly E. V. Swanson, Miran Mrkela, Helen C. Murray, Maize C. Cao, Clinton Turner, Maurice A. Curtis, Richard L. M. Faull, Adam K. Walker, Emma L. Scotter
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-22 (2023)
Abstract Microglia, the innate immune cells of the brain, are activated by damage or disease. In mouse models of amyotrophic lateral sclerosis (ALS), microglia shift from neurotrophic to neurotoxic states with disease progression. It remains unclear
Externí odkaz:
https://doaj.org/article/ffaa51da88b7483d88b75ccc62336f16
Autor:
Sarah Waters, Molly E. V. Swanson, Birger V. Dieriks, Yibin B. Zhang, Natasha L. Grimsey, Helen C. Murray, Clinton Turner, Henry J. Waldvogel, Richard L. M. Faull, Jiyan An, Robert Bowser, Maurice A. Curtis, Mike Dragunow, Emma Scotter
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease involving progressive degeneration of upper and lower motor neurons. The pattern of lower motor neuron loss along the spinal cord follows the pattern of deposition of p
Externí odkaz:
https://doaj.org/article/075e0657417440b8988eb257ce9ef0e0
Autor:
Molly E. V. Swanson, Emma L. Scotter, Leon C. D. Smyth, Helen C. Murray, Brigid Ryan, Clinton Turner, Richard L. M. Faull, Mike Dragunow, Maurice A. Curtis
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Abstract In Alzheimer’s disease (AD), microglia are affected by disease processes, but may also drive pathogenesis. AD pathology-associated microglial populations have been identified with single-cell RNA-Seq, but have not been validated in human b
Externí odkaz:
https://doaj.org/article/fd4bdb9a974b40289fbe32b437cd3db9
Autor:
Helen C. Murray, Birger Victor Dieriks, Molly E. V. Swanson, Praju Vikas Anekal, Clinton Turner, Richard L. M. Faull, Leonardo Belluscio, Alan Koretsky, Maurice A. Curtis
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Olfactory dysfunction is an early and prevalent symptom of Alzheimer’s disease (AD) and the olfactory bulb is a nexus of beta-amyloid plaque and tau neurofibrillary tangle (NFT) pathology during early AD progression. To mitigate the accumu
Externí odkaz:
https://doaj.org/article/e03ed8358b8a4a90b1985b46dadf7659
Autor:
Rosemary V. Swanson, Ananya Gupta, Taylor W. Foreman, Lan Lu, Jose Alberto Choreno-Parra, Stanley Kimbung Mbandi, Bruce A. Rosa, Sadia Akter, Shibali Das, Mushtaq Ahmed, Maria de la Luz Garcia-Hernandez, Dhiraj K. Singh, Ekaterina Esaulova, Maxim N. Artyomov, Jennifer Gommerman, Smriti Mehra, Joaquin Zuniga, Makedonka Mitreva, Thomas J. Scriba, Javier Rangel-Moreno, Deepak Kaushal, Shabaana A. Khader
Publikováno v:
Nature Immunology. 24:855-868
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::020de5abbf1564fcba9fd84c67aaa09d
https://doi.org/10.1038/s41590-023-01476-3
https://doi.org/10.1038/s41590-023-01476-3
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The current tuberculosis (TB) vaccine, Bacille Calmette-Guerin (BCG), is effective in preventing TB in young children but was developed without a basic understanding of human immunology. Most modern TB vaccine candidates have targeted CD4+ T cell res
Externí odkaz:
https://doaj.org/article/232d06d099f04601846b1f08e44c83e0
Autor:
Raul C. Camacho, Seohee You, Katharine E. D’Aquino, Wenyu Li, Yuanping Wang, Joseph Gunnet, James Littrell, Jian Shen Qi, Lijuan Kang, Wenying Jian, Mary MacDonald, Timothy Tat, Derek Steiner, Yue-Mei Zhang, James Lanter, Raymond Patch, Rui Zhang, Jiali Li, Suzanne Edavettal, Wilson Edwards, Thai Dinh, Li Ying Wang, Judy Connor, Michael Hunter, Ellen Chi, Ronald V. Swanson, James N. Leonard, Martin A. Case
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
The long circulating half-life and inherently bivalent architecture of IgGs provide an ideal vehicle for presenting otherwise short-lived G-protein-coupled receptor agonists in a format that enables avidity-driven enhancement of potency. Here, we des
Externí odkaz:
https://doaj.org/article/5eb7ffd685414dc1807d86d35890f6a4
Autor:
Justin Rustenhoven, Amy M. Smith, Leon C. Smyth, Deidre Jansson, Emma L. Scotter, Molly E. V. Swanson, Miranda Aalderink, Natacha Coppieters, Pritika Narayan, Renee Handley, Chris Overall, Thomas I. H. Park, Patrick Schweder, Peter Heppner, Maurice A. Curtis, Richard L. M. Faull, Mike Dragunow
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-16 (2018)
Abstract Background Microglia play critical roles in the brain during homeostasis and pathological conditions. Understanding the molecular events underpinning microglial functions and activation states will further enable us to target these cells for
Externí odkaz:
https://doaj.org/article/61d01fe126004e1d9256ea1766c25fa5
Autor:
Karen V. Swanson, Mustafa Girnary, Tomaz Alves, Jenny PY Ting, Kimon Divaris, Jim Beck, Carolina Maschietto Pucinelli, Raquel Assed Bezerra da Silva, Dilek Uyan, Justin E. Wilson, William T. Seaman, Jennifer Webster‐Cyriaque, Nishma Vias, Yizu Jiao, Lloyd Cantley, Arnaud Marlier, Roland R. Arnold, Julie T. Marchesan
Publikováno v:
Journal of Periodontology. 93:1366-1377
Periodontal destruction can be the result of different known and yet-to-be-discovered biological pathways. Recent human genetic association studies have implicated interferon-gamma inducible protein 16 (IFI16) and absent in melanoma 2 (AIM2) with hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccfc6ec186372cc4923d9caf186c80c
https://doi.org/10.1002/jper.21-0668
https://doi.org/10.1002/jper.21-0668