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P380 Changes in faecal microbiome and metabolome are more pronounced in Crohn’s disease patients who adhered to the CD-TREAT diet and responded by calprotectin

Autor: V Svolos, R Hansen, R K Russell, D R Gaya, J P Seenan, J Macdonald, D Wilson, P Henderson, S Din, G T Ho, C Quince, U Z Ijaz, S Milling, B Nichols, R Papadopoulou, S McKirdy, L Gervais, S Shields, K Gerasimidis

Publikováno v: Journal of Crohn's and Colitis. 17:i513-i515

Background Treatment with the CD-TREAT solid food diet improves disease activity indices, faecal calprotectin (FCAL) levels and quality of life in adults and children with active Crohn’s disease (CD); particularly in patients who adhere to the diet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eab0b656c79bc9f17acb1d6efb9b9ef4
https://doi.org/10.1093/ecco-jcc/jjac190.0510

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P804 Development and Validation of the Glasgow Exclusive Enteral Nutrition Index of Compliance (GENIE)

Autor: A Jatkowska, B White, B Nichols, V Svolos, K Gkikas, R Hansen, R K Russell, D Gaya, E Brownson, J P Seenan, S Milling, J MacDonald, K Gerasimidis

Publikováno v: Journal of Crohn's and Colitis. 17:i937-i938

Background Treatment adherence is key to the efficacy of exclusive enteral nutrition (100% EN) in active Crohn’s disease (CD), but there are currently no biomarkers to objectively support this. We explored faecal parameters as putative biomarkers o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::078f8e1db626f0e64c5f30d07c78b546
https://doi.org/10.1093/ecco-jcc/jjac190.0934

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DOP31 Gut metabolomic and compositional signatures predict response to treatment with exclusive enteral nutrition in children with active Crohn’s disease

Autor: K Gerasimidis, B Nichols, A Briola, J Havlik, A Mascellani, S Milling, U Ijaz, C Quince, V Svolos, R K Russell, R Hansen

Publikováno v: Journal of Crohn's and Colitis. 17:i96-i96

Background Predicting response to treatment with exclusive enteral nutrition (EEN) in paediatric Crohn’s disease (CD) can lead to more personalised, cost-effective, and efficacious therapy. We explored the ability of pre-treatment clinical and mult

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::93e95d52e8e4b0e429a1681f0bd0cd73
https://doi.org/10.1093/ecco-jcc/jjac190.0071

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DOP68 CD-TREAT diet induces remission and improves quality of life in an open label trial in children and adults with active Crohn’s Disease

Autor: V Svolos, R Hansen, R Russell, D R Gaya, S John Paul, J Macdonald, B Nichols, R Papadopoulou, M Logan, S Mckirdy, R Gervais, U Ijaz, S Milling, S Shields, D Wilson, P Henderson, S Din, G T Ho, K Gerasimidis

Publikováno v: Journal of Crohn's and Colitis. 16:i112-i112

Background Exclusive enteral nutrition (EEN) is an established induction treatment for active Crohn’s disease (CD) with a proposed mechanism of action involving the gut microbiome. We have previously shown that CD-TREAT diet, a food-based diet with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97d9257d266d68b29f731dfd189dc177
https://doi.org/10.1093/ecco-jcc/jjab232.107

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P326 The effect of compliance during exclusive enteral nutrition on faecal calprotectin levels in children with Crohn’s disease

Autor: S Mckirdy, R Russell, R Hansen, V Svolos, K Gkikas, M Logan, K Gerasimidis

Publikováno v: Journal of Crohn's and Colitis. 16:i347-i347

Background It is yet unclear whether suboptimal response to exclusive enteral nutrition (EEN), in some children with Crohn’s disease (CD), is explained by poor compliance. All proprietary feeds used for EEN are gluten-free; hence patients’ compli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63b67efcfbaf1b2b33dba9c62b9db7ce
https://doi.org/10.1093/ecco-jcc/jjab232.453

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P705 The effects of commonly consumed dietary fibres on the gut microbiome and its fibre fermentative capacity in adults with inflammatory bowel disease in remission

Autor: K Gerasimidis, B Nichols, M McGowan, V Svolos, R Papadopoulou, M Kokkorou, M Rebull, T Bello Gonzalez, R Hansen, R K Russell, D R Gaya

Publikováno v: Journal of Crohn's and Colitis. 16:i602-i602

Background It has been suggested that the gut microbiome of patients with inflammatory bowel disease (IBD) is unable to ferment dietary fibre. This project explored the in vitro effect of fibre fermentation on production of short chain fatty acids (S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::392351ea0e66af91b44a5c47b49fa663
https://doi.org/10.1093/ecco-jcc/jjab232.826

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