Zobrazeno 1 - 10 of 10 pro vyhledávání: '"V S, Latter"'
1
Efficacy of a hydroxynaphthoquinone, 566C80, in experimental Pneumocystis carinii pneumonitis
Autor: M. Pudney, V L Gray, Walter T. Hughes, W E Gutteridge, V S Latter
Publikováno v: Antimicrobial Agents and Chemotherapy. 34:225-228
The efficacy of a new class of drugs for Pneumocystis carinii pneumonitis was demonstrated. 566C80, a hydroxynaphthoquinone, administered orally in a dose of greater than or equal to 100 mg/kg of body weight per day prophylactically prevented P. cari
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb6a1d6660237c7cd58e91025c77e5e
https://doi.org/10.1128/aac.34.2.225
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2
566C80: a potent broad spectrum anti-infective agent with activity against malaria and opportunistic infections in AIDS patients
Autor: A T, Hudson, M, Dickins, C D, Ginger, W E, Gutteridge, T, Holdich, D B, Hutchinson, M, Pudney, A W, Randall, V S, Latter
Publikováno v: Drugs under experimental and clinical research. 17(9)
566C80 is a novel hydroxynaphthoquinone with broad-spectrum anti-parasitic properties. In vitro the compound was more potent against Plasmodium falciparum than any of the established anti-malarial drugs. It had good activity against the pathogen in A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9002d32b5fb30091640bc9de4f4f59e0
https://pubmed.ncbi.nlm.nih.gov/1822435
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3
Novel anti-malarial hydroxynaphthoquinones with potent broad spectrum anti-protozoal activity
Autor: N. Mchardy, M. Fry, A. W. Randall, C. D. Ginger, Alan Thomas Hudson, V. S. Latter, B. Hill, R. B. Williams
Publikováno v: Parasitology. 90:45-55
Novel hydroxynaphthoquinones are reported with outstanding efficacy against Plasmodium, Eimeria and Theileria species. Biochemical evidence is presented for the selective toxicity of these compounds being due to inhibition of parasite respiratory sys
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac24141a56ea977d6aa0fbaa9864bbaf
https://doi.org/10.1017/s0031182000049003
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4
Pyrazolo[3,4-d]pyrimidine ribonucleosides as anticoccidials. 3. Synthesis and activity of some nucleosides of 4-[(arylalkenyl)thio]pyrazolo[3,4-d]pyrimidines
Autor: J L, Rideout, T A, Krenitsky, E Y, Chao, G B, Elion, R B, Williams, V S, Latter
Publikováno v: Journal of Medicinal Chemistry. 26:1489-1494
Ribonucleosides of 4-(alkylthio)-1H-pyrazolo[3,4-d]pyrimidines have been shown to be useful anticoccidial agents [Krenitsky, T. A.; Rideout, J. L.; Koszalka, G. W.; Inmon, R. B.; Chao, E. Y.; Elion, G. B.; Latter, V. S.; Williams, R. B. J. Med. Chem.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7e8670837e4c95e8dde193eb4631c63
https://doi.org/10.1021/jm00364a024
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7
The sporulation of Eimeria tenella as revealed by a novel preparative method
Autor: V. S. Latter, J. E. Beesley
Publikováno v: Zeitschrift fur Parasitenkunde (Berlin, Germany). 67(3)
A simple technique for obtaining ultra-thin sections of coccidian oocysts is reported. Oocyst walls, the main barriers to fixatives, dehydrating agents and embedding media are ruptured by brief immersion of the organism in liquid nitrogen. Adequate p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0746ee5aec14ac26af6fcdd2351871b
https://pubmed.ncbi.nlm.nih.gov/7136188
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