Zobrazeno 1 - 10
of 61
pro vyhledávání: '"V R, Chechetkin"'
Autor:
Vasily V. Lobzin, V. R. Chechetkin
A world-wide COVID-19 pandemic intensified strongly the studies of molecular mechanisms related to the coronaviruses. The origin of coronaviruses and the risks of human-to-human, animal-to-human, and human-to-animal transmission of coronaviral infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce99a140e05783b347d6b0326687739
Autor:
Vasily V. Lobzin, V. R. Chechetkin
Publikováno v:
Journal of Biomolecular Structure & Dynamics
article-version (VoR) Version of Record
Journal of Biomolecular Structure and Dynamics
article-version (VoR) Version of Record
Journal of Biomolecular Structure and Dynamics
The genomic ssRNA of coronaviruses is packaged within a helical nucleocapsid. Due to transitional symmetry of a helix, weakly specific cooperative interaction between ssRNA and nucleocapsid proteins leads to the natural selection of specific quasi-pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b8bc1fd9f0752f1e4b3d1c4875e4a6e
http://arxiv.org/abs/2007.10274
http://arxiv.org/abs/2007.10274
Autor:
V. R. Chechetkin, V. V. Lobzin
In many processes, the variations in underlying characteristics can be approximated by noisy multi-periodic patterns. If large-scale patterns are superimposed by a noise with long-range correlations, the detection of multi-periodic patterns becomes e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd8f93330f3651c9113458644b5c9b82
http://arxiv.org/abs/1912.02230
http://arxiv.org/abs/1912.02230
Autor:
O. V. Kretova, M. A. Gorbacheva, D. M. Fedoseeva, Y. V. Kravatsky, V. R. Chechetkin, N. A. Tchurikov
Publikováno v:
Molecular Biology. 52:510-513
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4f1d7448579d195f46298902fb29184
https://doi.org/10.1134/s0026893318040118
https://doi.org/10.1134/s0026893318040118
Autor:
Maria A. Gorbacheva, Nickolai A. Tchurikov, Y. V. Kravatsky, V. R. Chechetkin, Olga V. Kretova, D. M. Fedoseeva
Publikováno v:
Molecular Biology. 52:393-397
HIV-1 is one of the most variable viruses. The development of gene therapy technology using RNAi for AIDS/HIV-1 treatment is a potential alternative for traditional anti-retroviral therapy. Anti-HIV-1 siRNA should aim to exploit the most conserved vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a84e881cdae985f1c1e8284f2af89b1
https://doi.org/10.1134/s002689331803007x
https://doi.org/10.1134/s002689331803007x
Autor:
D. M. Fedoseeva, Olga V. Kretova, Maria A. Gorbacheva, Y V Kravatskya, V. R. Chechetkin, Nickolai A. Tchurikov
Publikováno v:
Молекулярная биология. 52:591-594
Gene therapy for AIDS based on RNA interference (RNAi) is currently looked upon as a promising alternative to conventional antiretroviral chemotherapy. The high variability of HIV-1 is the main challenge in developing new approaches to AIDS therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a24101a2663bd0099a0728d3947b605
https://doi.org/10.1134/s0026898418040110
https://doi.org/10.1134/s0026898418040110
Autor:
D. M. Fedoseeva, Nataliya V. Melnikova, Maria A. Gorbacheva, Yuri V. Kravatsky, V. R. Chechetkin, Maria P. Gashnikova, Olga V. Kretova, Natalya M. Gashnikova, Nickolai A. Tchurikov
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss, Pp 330-344 (2017)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
RNAi has been suggested for use in gene therapy of HIV/AIDS, but the main problem is that HIV-1 is highly variable and could escape attack from the small interfering RNAs (siRNAs) due to even single nucleotide substitutions in the potential targets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f771ded70583ccf64ba886ac3b33c16
http://www.sciencedirect.com/science/article/pii/S2162253117302202
http://www.sciencedirect.com/science/article/pii/S2162253117302202
Autor:
D. M. Fedoseeva, Nickolai A. Tchurikov, Yuri V. Kravatsky, V. R. Chechetkin, Olga V. Kretova, Ivan Y Slovohotov, E. S. Klushevskaya
Publikováno v:
Cells
Volume 8
Issue 11
Cells, Vol 8, Iss 11, p 1393 (2019)
Volume 8
Issue 11
Cells, Vol 8, Iss 11, p 1393 (2019)
Human rDNA clusters form numerous contacts with different chromosomal regions as evidenced by chromosome conformation capture data. Heterochromatization of rDNA genes leads to heterochromatization in different chromosomal regions coupled with the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f299e8af37870b6a1069df7104f79051
Autor:
Nickolai A. Tchurikov, V. R. Chechetkin, Maria A. Gorbacheva, Olga V. Kretova, D. M. Fedoseeva, Natalya M. Gashnikova, Yuri V. Kravatsky, Dmitri V. Sosin, Ildar R. Alembekov
Publikováno v:
Gene. 583:78-83
Highly active antiretroviral therapy has greatly reduced the morbidity and mortality of AIDS. However, many of the antiretroviral drugs are toxic with long-term use, and all currently used anti-HIV agents generate drug-resistant mutants. Therefore, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd1ba0392f564bfa77d4916b3fd3ec1
https://doi.org/10.1016/j.gene.2016.03.001
https://doi.org/10.1016/j.gene.2016.03.001
Autor:
Y. V. Kravatsky, V. R. Chechetkin, D. M. Fedoseeva, M. A. Gorbacheva, O. V. Kretova, N. A. Tchurikov
Publikováno v:
Molecular Biology. 50:417-421
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f8dd6bba91626bed0da9bc12a2ef004
https://doi.org/10.1134/s0026893316020114
https://doi.org/10.1134/s0026893316020114