Zobrazeno 1 - 10
of 22
pro vyhledávání: '"V P, Shirinskiĭ"'
Publikováno v:
Терапевтический архив, Vol 80, Iss 8, Pp 63-65 (2008)
Aim. To study activity of rheumatoid arthritis (RA) and cholesterol content in subfractions of blood serum lipoproteins in the course of simvastatin treatment. Material and methods. The pilot study enrolled 16 patients with active rheumatoid arthriti
Externí odkaz:
https://doaj.org/article/b2ccefef48e9437b94f258a7bc31a6d3
Autor:
A Iu, Khapchaev, M V, Samsonov, O A, Kazakova, E L, Vilitkevich, M V, Sidorova, A A, Az'muko, A S, Molokoedov, Zh D, Bespalova, V P, Shirinskiĭ
Publikováno v:
Biofizika. 57(5)
Novel peptides originating from the peptide inhibitor of myosin light chain kinase, L-PIK (Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys), have been studied for ability to attenuate the thrombin-induced hyperpermeability of endothelial cell monolayer in cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::338cdd709400bb1909f0581a8d03cad0
https://pubmed.ncbi.nlm.nih.gov/23136768
https://pubmed.ncbi.nlm.nih.gov/23136768
Autor:
E V, Shreĭder, E V, Bazaeva, O V, Stukalova, M A, Saidova, A V, Chadin, V P, Shirinskiĭ, A N, Meshkov, A N, Samko, E P, Mazygula, S A, Boĭtsov
Publikováno v:
Kardiologiia. 52(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c1e628797f75fce4df71e8be82b47b5
https://pubmed.ncbi.nlm.nih.gov/22304360
https://pubmed.ncbi.nlm.nih.gov/22304360
Autor:
A V, Marchenko, E O, Stepanova, A V, Sekridova, M V, Sidorova, V N, Bushuev, Zh D, Bespalova, V P, Shirinskiĭ
Publikováno v:
Biofizika. 55(6)
The ability of novel cell-permeating peptide molecules derived from the peptide inhibitor of the myosin light chain kinase (MLCK) L-PIK (Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys) to inhibit this kinase in vitro and attenuate the thrombin-induced hyperperm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f318dd503e14b226ff8d35ed85cab0b
https://pubmed.ncbi.nlm.nih.gov/21268344
https://pubmed.ncbi.nlm.nih.gov/21268344
Autor:
O V, Stepanova, A V, Chadin, A G, Masiutin, T G, Kulikova, Ia V, Gurin, I A, Sergeeva, V P, Shirinskiĭ
Publikováno v:
Biofizika. 55(5)
It has been shown that Y-27632, an inhibitor of Rho-associated kinase, delays sarcomere assembly in rat neonatal cardiomyocytes pretreated with angiotensin II. Y-27632 affects the beat rate of cardiomyocytes; however, this effect is only observed at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abf726899ab3649559272baaf1aed27a
https://pubmed.ncbi.nlm.nih.gov/21033356
https://pubmed.ncbi.nlm.nih.gov/21033356
Autor:
A V, Sekridova, M V, Sidorova, A A, Az'muko, A S, Molokoedov, V N, Bushuev, A V, Marchenko, O V, Shcherbakova, V P, Shirinskiĭ, Zh D, Bespalova
Publikováno v:
Bioorganicheskaia khimiia. 36(4)
Myosin light chain kinase (MLCK) is the key regulator of various forms of cell motility including endothelial and epithelial permeability in particular. One of the potential MLCK inhibitors to be used in humans is a membrane permeable peptide H-RKKYK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::80d11c8e182d375be92200d761fd6e5a
https://pubmed.ncbi.nlm.nih.gov/20823918
https://pubmed.ncbi.nlm.nih.gov/20823918
Autor:
A V, Vorotnikov, O V, Shchrbakova, T V, Kudriashova, O S, Tarasova, V P, Shirinskiĭ, G, Pfitzer, V A, Tkachuk
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 95(10)
Rho-kinase is a key enzyme of the receptor-dependent signal cascades and is regarded today as the most prospective target for pharmacological therapy of smooth muscle contractility disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a4771810ed641d9ba9ad78d21e38adf
https://pubmed.ncbi.nlm.nih.gov/19957896
https://pubmed.ncbi.nlm.nih.gov/19957896
Autor:
A V, Marchenko, M V, Sidorova, A V, Sekridova, V N, Bushuev, V L, Lakomkin, Ts R, Orlova, O V, Stepanova, V I, Kapel'ko, D M, Watterson, L J, Van Eldik, Zh D, Bespalova, V P, Shirinskiĭ
Publikováno v:
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 95(5)
Nonapeptide H-Arg-Lys-Lys-Tyr-Lys-Tyr-Arg-Arg-Lys-NH2 corresponding to a modified sequence of autoinhibitory region of myosin light chain kinase (MLCK) was synthesized from L-amino acids and from D-amino acids. Using nuclear magnetic resonance spectr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62f66ef98cf6b470c03b8f2c39d680a3
https://pubmed.ncbi.nlm.nih.gov/19569527
https://pubmed.ncbi.nlm.nih.gov/19569527
Publikováno v:
Molekuliarnaia biologiia. 42(5)
This review analyzes the current state in investigations of molecular, genetic and cellular mechanisms of cardiac development as well as perspectives to use this knowledge for treatment of cardiac failure by means of replenishing cardiomyocytes in da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::021a9bc851d5cc198451b6bf029d2ed4
https://pubmed.ncbi.nlm.nih.gov/18988534
https://pubmed.ncbi.nlm.nih.gov/18988534
Publikováno v:
Biofizika. 51(5)
The skeletal myosin light chain kinase (skMLCK) was identified in human and chicken embryo myocardium but not in embryo and adult rat heart using western blotting. The content of skMLCK and myosin-activating protein kinases: RhaA-activated protein ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9085b11c44890db254287d1aaee6f51d
https://pubmed.ncbi.nlm.nih.gov/17131835
https://pubmed.ncbi.nlm.nih.gov/17131835