Výsledky vyhledávání - "V P, Addonizio"

Effects of simulated extracorporeal circulation on human leukocyte elastase release, superoxide generation, and procoagulant activity

Autor: G. Weinbaum, R. F. Stahl, Umberto Kucich, Nina Stenach, C. O'connor, V. P. Addonizio, David S. Warsaw, Carol A. Fisher

Publikováno v: The Journal of Thoracic and Cardiovascular Surgery. 101:230-239

Activated leukocytes are thought to contribute to respiratory dysfunction, alterations in microvascular permeability, disseminated intravascular coagulation, and thrombosis, all of which can complicate extracorporeal circulation. The purpose of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96e6ae3044b606976184ace04260e986
https://doi.org/10.1016/s0022-5223(19)36757-1

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Increased activation of the coagulation and fibrinolytic systems leads to hemorrhagic complications during left ventricular assist implantation

Autor: E R, Livingston, C A, Fisher, E J, Bibidakis, A S, Pathak, B A, Todd, S, Furukawa, J B, McClurken, V P, Addonizio, V, Jeevanandam

Publikováno v: Circulation. 94

Left ventricular assist devices (LVADs) have provided a new therapeutic option for patients with end-stage heart failure. Despite advances in device design, there remains an apparent bleeding diathesis, which leads to increased transfusion requiremen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea20337099c5afd6fb33e54ce61314a6
https://pubmed.ncbi.nlm.nih.gov/9355922

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Adult orthotopic heart transplantation using undersized pediatric donor hearts. Technique and postoperative management

Autor: V, Jeevanandam, P, Mather, S, Furukawa, B, Todd, T, Regillo, A A, Bove, J, McClurken, V P, Addonizio

Publikováno v: Circulation. 90(5 Pt 2)

Because of the critical shortage of adult donor hearts, many recipients die awaiting transplantation of an organ of appropriate size. Undersized hearts (donor/recipient weight ratio0.7) have been used for heterotopic heart transplantation. We report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dc21e80e4bad3da68287b51efa1b4ea1
https://pubmed.ncbi.nlm.nih.gov/7955288

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The effects of heparin bound surface modification (Carmeda Bioactive Surface) on human platelet alterations during simulated extracorporeal circulation

Autor: N, Stenach, R L, Korn, C A, Fisher, V, Jeevanandam, V P, Addonizio

Publikováno v: The journal of extra-corporeal technology. 24(3)

To determine if treatment with covalently bound heparin (Carmeda Bioactive Surface (CBAS)) to the synthetic surface of the extracorporeal circuit (ECC) would alter the stereotypic pattern of adverse platelet alterations, 450 ml of heparinized blood (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bb408e9f24fc9502a424a5e060b7337
https://pubmed.ncbi.nlm.nih.gov/10148074

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Effects of simulated extracorporeal circulation on human leukocyte elastase release, superoxide generation, and procoagulant activity

Autor: R F, Stahl, C A, Fisher, U, Kucich, G, Weinbaum, D S, Warsaw, N, Stenach, C, O'Connor, V P, Addonizio

Publikováno v: The Journal of thoracic and cardiovascular surgery. 101(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::829f1ce8b0c829171fce8dcd2c48e8c6
https://pubmed.ncbi.nlm.nih.gov/1846928

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Platelet function in cardiopulmonary bypass and artificial organs

Autor: V P, Addonizio

Publikováno v: Hematology/oncology clinics of North America. 4(1)

Extensive contact between blood and synthetic surfaces is associated with both quantitative and qualitative changes in platelet function. Cardiopulmonary bypass is associated with a decline in the circulating platelet count, release of platelet alpha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8f346091ed7e72ed04c2e343fe549679
https://pubmed.ncbi.nlm.nih.gov/2179210

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Assay of prekallikrein in human plasma: comparison of amidolytic, esterolytic, coagulation, and immunochemical assays

Autor: C A, Fisher, A H, Schmaier, V P, Addonizio, R W, Colman

Publikováno v: Blood. 59:963-970

Using the substrate H-D-Pro-Phe-Arg-p-nitroanilide-HCl, an amidolytic assay was designed to measure prekallikrein in plasma. At a substrate concentration of 1 mM (Km = 0.2 mM), the amidolysis of purified kallikrein at 1 coagulant unit/ml was observed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8e91f21b3a81c9e1474f732373858a
https://doi.org/10.1182/blood.v59.5.963.bloodjournal595963

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Preservation of human platelets with prostaglandin E1 during in vitro simulation of cardiopulmonary bypass

Autor: S Niewiarowski, Robert W. Colman, Edmunds Lh, V P Addonizio, Macarak Ej

Publikováno v: Circulation Research. 44:350-357

spiral coil membrane oxygenator. Platelet counts fall to 20% of initial levels, plasma levels of low affinity platelet factor 4 (LA-PF4) rise from 0 to 66% of that in control platelet rich plasma, and sensitivity to aggregating agents diminishes. Inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723c186f37cda3387a3efbe5b5c0a117
https://doi.org/10.1161/01.res.44.3.350

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