Výsledky vyhledávání - "V O Topuzyan"

Synthesis and Anticholinesterase Activity of [(4Z)-2-Aryl-4-(arylmethylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]alkanoic Acids

Autor: V. O. Topuzyan, Rafael Tamazyan, A. G. Aivazyan, L. Kh. Galstyan, V. M. Kazoyan

Publikováno v: Russian Journal of Organic Chemistry. 54:1369-1377

ω-[(4Z)-2-Aryl-4-arylmethylidene-5-oxo-4,5-dihydro-1H-imidazol-1-yl]alkanoic acids were synthesized by reaction of N-substituted α,β-dehydropeptides with chloro(trimethyl)silane or 1,1,1,3,3,3-hexamethyldisilazane. Both initial peptides and (4H)-i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b62393f4c1221a47362630558348603a
https://doi.org/10.1134/s1070428018090178

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Synthesis, Anticholinesterase, and Antibacterial Activity of N-Aroyl-a-Aminoacrylic Acid Dialkylaminoalkylamides

Autor: V. O. Topuzyan, R. V. Paronikyan, Z. G. Alebyan

Publikováno v: Pharmaceutical Chemistry Journal. 49:304-308

N-Aroyl-α-aminoacrylic acid 2-(dialkylamino)alkylamides and their quaternary ammonium salts were synthesized and their physicochemical properties were determined. Results obtained from studies of their interactions with human erythrocyte acetylcholi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::435372b000eb83683639946377ba64aa
https://doi.org/10.1007/s11094-015-1274-0

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Derivatives of α,β-dehydro amino acids: VI. Reaction of 4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one with piperidin-2-ylmethanamine

Autor: V. O. Topuzyan, A. G. Aivazyan, V. V. Grigoryan, Rafael Tamazyan, A. R. Manvelyan

Publikováno v: Russian Journal of Organic Chemistry. 49:886-889

4-Benzylidene-2-phenyl-1,3-oxazol-5(4H)-one reacts with piperidin-2-ylmethanamine to give N-{(Z)-3-oxo-3-[(piperidin-2-ylmethyl)amino]-1-phenylprop-1-en-2-yl}benzamide, N-(4-benzyl-3-oxooctahydro-2N-pyrido[1,2-a]pyrazin-4-yl)benzamide, or/and (Z)-4-b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f041210d116be5f04ebe4175e48f41b5
https://doi.org/10.1134/s1070428013060146

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Synthesis and Anticholinesterase Properties of Choline esters of α-Amino Acids

Autor: I. R. Karapetyan, V. O. Topuzyan, G. P. Alebyan

Publikováno v: Pharmaceutical Chemistry Journal. 48:163-165

2-(Dimethylamino)ethyl esters of a number of N-substituted α-amino acids and their quaternary ammonium salts were synthesized and their physiochemical properties were determined. We report here studies of their interactions with erythrocyte acetylch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6bc9340009a715383c177317def89f2d
https://doi.org/10.1007/s11094-014-1070-2

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Derivatives of α,β-dehydro amino acids: III. Reaction of 4-arylmethylidene-4,5-dihydro-1,3-oxazol-5-ones with hexamethyldisilazane

Autor: A. A. Oganesyan, L. G. Arutyunyan, V. O. Topuzyan

Publikováno v: Russian Journal of Organic Chemistry. 43:868-871

4-Arylmethylidene-4,5-dihydro-1,3-oxazol-5-ones reacted with hexamethyldisilazane in ethyl acetate, acetonitrile, or DMF at room temperature to give mainly 2-acylamino-3-arylmethylideneprop-2-enamides, whereas in boiling DMF the corresponding 4-arylm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4f934f744f6149b2d154f417ba539b5
https://doi.org/10.1134/s1070428007060127

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