Zobrazeno 1 - 10
of 16
pro vyhledávání: '"V N, Tashlitskiĭ"'
Autor:
M V, Dariĭ, A R, Rakhimova, V N, Tashlitskiĭ, S V, Kostiuk, N N, Veĭko, A A, Ivanov, A L, Zhuze, E S, Gromova
Publikováno v:
Molekuliarnaia biologiia. 47(2)
Cancer cells are characterized by the hypermethylation of promoter regions of tumor suppressor genes. DNA methyltransferase inhibitors cause re-activation of these genes that allows considering DNA methyltransferases as targets for anticancer therapy
Autor:
E K, Fetisova, A V, Avetisian, D S, Iziumov, M V, Korotetskaia, V N, Tashlitskiĭ, V P, Skulachev, B V, Cherniak
Publikováno v:
Tsitologiia. 52(12)
Mitochondria-targeted antioxidants of the SkQR1 family, being accumulated in energized mitochondria, protect cells from oxidative stress by increasing the level of reduced glutathione and decreasing the cell-damaging effect induced by hydrogen peroxi
Autor:
M B, Gottikh, V N, Tashlitskiĭ
Publikováno v:
Vestnik oftalmologii. 126(5)
Bilberry has been long used in folk medicine and credited for an ability to improve vision, primarily night vision. The major active ingredients of bilberries are antocyans. Experimental and clinical studies confirmed the ability of bilberry antocyan
Autor:
S P, Korolev, V N, Tashlitskiĭ, M A, Smolov, A V, Gromyko, A L, Zhuze, Iu Iu, Agapkina, M B, Gottikh
Publikováno v:
Molekuliarnaia biologiia. 44(4)
HIV-1 integrase is responsible for one of the key steps of the viral replication, integration of the viral cDNA into the host cell genome. Integration inhibition leads to complete block of the virus replication. In this study inhibition of integratio
Publikováno v:
Bioorganicheskaia khimiia. 29(3)
Conjugates of amines or short peptides with oligonucleotides containing 5'-terminal carboxyl group were prepared by solid phase chemical synthesis. A correlation between the physicochemical parameters and retention times of the synthesized conjugates
Publikováno v:
Biofizika. 46(6)
The notion of the DNA-recognizing segment of a protein for three-dimensional structures of DNA-protein complexes was formalized. Algorithms for calculating two parameters, hydrogen bonds and hydrophobic contacts, that characterize the interaction of
Publikováno v:
Molekuliarnaia biologiia. 34(1)
Autor:
E M, Zubin, S I, Antsypovich, T S, Oretskaya, E A, Romanova, E M, Volkov, V N, Tashlitskiĭ, Z A, Shabarova
Publikováno v:
Bioorganicheskaia khimiia. 23(10)
A method for preparing a modified derivative of 2'-amino-2'-deoxy-arabino-adenosine ready for directed insertion into an oligonucleotide chain during solid-phase synthesis was elaborated. A series of the title oligonucleotides (6-25-mers) containing
Publikováno v:
Biokhimiia (Moscow, Russia). 61(7)
The effect of correlations between kinetic parameters of two inducible substrates on allosteric activation of EcoRII endonuclease hydrolysis of one substrate was studied. The pairs of DNA duplexes were constructed that were the substrates of EcoRII r
Autor:
S I, Antsypovich, T S, Oretskaia, E A, Romanova, E M, Volkov, V N, Tashlitskiĭ, M, Vasseur, Z A, Shabarova
Publikováno v:
Bioorganicheskaia khimiia. 22(4)
Synthesis of cross-linked modified DNA duplexes is described. The structure of the duplexes was confirmed by digestion with the AluI restriction endonuclease. Thermostability and resistance to enzymatic hydrolysis of the cross-linked duplexes were st