Zobrazeno 1 - 10
of 53
pro vyhledávání: '"V N, Prozorovskiĭ"'
Autor:
M A Sanzhakov, O. M. Ipatova, E G Tikhonova, V N Prozorovskiĭ, N V Medvedeva, T I Tarkhovskaia
Publikováno v:
Biomeditsinskaya Khimiya. 59:585-590
Low bioavailability of rifampicin, one of the main antituberculous drug, stimulates searches of its new optimized formulations. The present study has showen possibility of rifampicin embedding into nanoparticles from plant phosphatidylcholine (diamet
Autor:
N V Medvedeva, E G Tikhonova, V N Prozorovskiĭ, A V Shironin, T S Zakharova, T I Torkhovskaia, O. M. Ipatova, M A Sanzhakov
Publikováno v:
Biomeditsinskaya Khimiya. 57:671-676
The ultrafine formulation on the base of plant phosphatidylcholine and antiinflammatory remedy indomethacin with nanoparticles less than 50 nm was obtained. Drug bioavailability after its peroral administration to rats was more than 2 fold higher as
Publikováno v:
Biomeditsinskaia khimiia. 60(6)
One of the main ways to increase the effectiveness of well-known medical formulations well-established in clinical medicine - development of delivery systems using new technological approaches and nanomaterials. Currently, much attention is given to
Autor:
M A, Sanzhakov, O M, Ipatova, T I, Torkhovskaia, V N, Prozorovskiĭ, E G, Tikhonova, O S, Druzhilovskaia, N V, Medvedeva
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (8)
The increase of tuberculosis incidence in last decade stimulated elaboration of both new antituberculous drugs and also searches ofoptimiting delivery systems for existing drugs. It is determined by their side effects and low bioavailability of effec
Autor:
A V, Shironin, O M, Ipatova, N V, Medvedeva, V N, Prozorovskiĭ, E G, Tikhonova, T S, Zakharova, M A, Sanzhakov, T I, Torkhovskaia
Publikováno v:
Biomeditsinskaia khimiia. 57(6)
The ultrafine formulation on the base of plant phosphatidylcholine and antiinflammatory remedy indomethacin with nanoparticles less than 50 nm was obtained. Drug bioavailability after its peroral administration to rats was more than 2 fold higher as
Autor:
T I Torkhovskaia, V. S. Baranova, Alexander I. Archakov, N. D. Ivanova, A V Shironin, N V Medvedeva, V N Prozorovskiĭ, O. M. Ipatova
Publikováno v:
Biomeditsinskaia khimiia. 56(1)
The recent studies in nanotechnology resulted in the development of novel formulations with improved bioavailability. This is especially important for oral administered drugs as the most convenient formulations. The current review deals with the proc
Publikováno v:
Biomeditsinskaia khimiia. 55(2)
The complexes of phospholipids nanoparticles (as the injection form of newly developed hepatoprotector phosphogliv) with the antitumor drug doxorubicin or with glucocorticoid budesonide have been investigated for their pharmacological activity in com
Publikováno v:
Biomeditsinskaia khimiia. 53(4)
The efficiency of methotrexate use in basic therapy of rheumatoid arthritis is limited because of risk of side effects and fast drug efflux from zone of joints as well. The new stabilized form of methotrexate was elaborated with phospholipid micelles
Publikováno v:
Biomeditsinskaia khimiia. 51(1)
The antioxidant action of the extract from Aronia melanocarpa leaves on the brain was investigated. The intraperitoneal injection of extract in the dose of 0.2 g/kg prevented manifestations of oxidative stress in the brain induced by immobilization o
Publikováno v:
Biomeditsinskaia khimiia. 49(1)
On the basis of analysis of own and literature data on insulin-receptor interaction two centers responsible for receptor binding were identified on 3D-structure of insulin with receptor. Two extracellular domains of insulin receptor interact with the