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pro vyhledávání: '"V M Kindt"'
Autor:
C S Lin, Richard K. Harrison, Francis J. Dumont, Samuel Koprak, V M Kindt, Sewell Tonya J, Mathew J. Wyvratt, Thomas R. Beattie, John Siekierka, Mary-Jo Staruch
Publikováno v:
The Journal of Experimental Medicine
FK-506 inhibits Ca(2+)-dependent transcription of lymphokine genes in T cells, and thereby acts as a powerful immunosuppressant. However, its potential therapeutic applications may be seriously limited by several side effects, including nephrotoxicit