Zobrazeno 1 - 10
of 21
pro vyhledávání: '"V M Gordon"'
Publikováno v:
Clinical and Translational Science
Autor:
James E. Samuel, V M Gordon
Publikováno v:
Journal of Biological Chemistry. 269:4853-4859
The role for proteolytic activation of Shiga-like toxin type II variant (SLT-IIv) A subunit was examined using site-directed mutagenesis. Processing of the enzymatically active A subunit by trypsin results in cleavage at an arginine residue(s) (Arg24
An enzymatic mutant of Shiga-like toxin II variant is a vaccine candidate for edema disease of swine
Publikováno v:
Infection and Immunity. 60:485-490
Edema disease (ED) of weanling pigs is caused by an infection with Escherichia coli that produces Shiga-like toxin II variant (SLT-IIv). Pathology identical to that caused by ED can be duplicated in pigs that are injected with less than 10 ng of puri
Autor:
Lloyd S. Gray, Ingrid Ehrmann, Margaretta Allietta, Erik L. Hewlett, V M Gordon, Mary C. Gray
Publikováno v:
Journal of Biological Chemistry. 266:17503-17508
Adenylate cyclase (AC) toxin from Bordetella pertussis interacts with and enters eukaryotic cells to catalyze the production of supraphysiologic levels of cyclic AMP. Although the calmodulin-activated enzymatic activity (ability to convert ATP to cyc
Publikováno v:
Gut. 60:A250-A251
Introduction The NHS Plan in July 2000 gave cancer services a high priority and government backing for reform of cancer services in England. One of the aims was to promote early detection of cancer. This led to introduction of 2-week wait for diagnos
Publikováno v:
Gut. 62:A283.1-A283
Introduction The ‘Registrar of the Week’ service initially started in response to a Primary Care Trust initiative for Gastroenterology advice to GP’s. This started as project ‘Batphone’. The Gastroenterology department saw an ideal opportun
Publikováno v:
Gut. 62:A203.2-A203
Introduction Good nutrition is an effective intervention in decompensated liver disease 1 . Protein Energy Malnutrition (PEM) is found in 65–90% of patients with advanced liver disease and almost 100% of those awaiting transplant 1 . There is an as
Autor:
V M, Gordon, F O, Bonkovsky
Publikováno v:
The Journal of clinical ethics. 7(4)
Publikováno v:
Infection and immunity. 64(1)
Escherichia coli strains producing Shiga-like toxin II variant (SLT-IIe, formerly called SLT-IIv) cause edema disease in weaned pigs. Vaccination of pigs with a genetically modified form of Shiga-like toxin IIe, SLT-IIe(E167Q), has been previously sh
Autor:
J E, Samuel, V M, Gordon
Publikováno v:
The Journal of biological chemistry. 269(7)
The role for proteolytic activation of Shiga-like toxin type II variant (SLT-IIv) A subunit was examined using site-directed mutagenesis. Processing of the enzymatically active A subunit by trypsin results in cleavage at an arginine residue(s) (Arg24