Zobrazeno 1 - 10
of 27
pro vyhledávání: '"V M, Tischenko"'
Publikováno v:
Molecular Immunology. 92:199-210
Human IgG4 (hIgG4) has weak pro-inflammatory activity. The structural basis for this is still unclear. Here a 3D model of myeloma hIgG4 was created at ∼3nm resolution using electron microscopy (EM) with negative staining and single-particle 3D reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ddb00bc8264f9e48f7edc14bad8347b
https://doi.org/10.1016/j.molimm.2017.10.014
https://doi.org/10.1016/j.molimm.2017.10.014
Autor:
V. M. Tischenko
Publikováno v:
Biochemistry (Moscow). 80:21-30
A long-lived metastable minor fraction has been detected and characterized in myeloma protein IgG4 MAM by hydro- and thermodynamic methods. The sedimentation constants of the minor and the major protein fractions are different. The stability of the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e48970bf0c19473dc30e6f485166ddaf
https://doi.org/10.1134/s0006297915010034
https://doi.org/10.1134/s0006297915010034
Autor:
D. A. Prohorov, V. M. Tischenko
Publikováno v:
Biophysics. 58:460-464
Several experimental methods (circular dichroism, viscosity, intrinsic fluorescence, and fluorescence labeling) were used to study the conformational folding/unfolding transitions in a compact monomeric form of the Caf113-149 subunit under the action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da47fff7fcaeb74be44c603c3f91046e
https://doi.org/10.1134/s0006350913040155
https://doi.org/10.1134/s0006350913040155
Autor:
M. A. Timchenko, V. M. Tischenko
Publikováno v:
Biochemistry (Moscow). 78:667-673
Fc fragments (hFc) of human myeloma IgG2 proteins LOM and SIN having core hinge (Cys-Cys-Val-Glu-Cys-Pro-Pro-Cys) were first obtained by a modified proteolytic procedure. The thermostability of CH2 domains inside of standard Fc, hFc fragments, and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e9b858a1d7a57e713507c9a15fefe4
https://doi.org/10.1134/s0006297913060126
https://doi.org/10.1134/s0006297913060126
Autor:
Xiaodi Yu, Stefan D. Knight, V. M. Tischenko, Anton V. Zavialov, Sheila MacIntyre, Elham Moslehi-Mohebi, L.J. Fooks, G. Askarieh
Publikováno v:
Journal of Molecular Biology. 417:294-308
The chaperone/usher pathway assembles surface virulence organelles of Gram-negative bacteria, consisting of fibers of linearly polymerized protein subunits. Fiber subunits are connected through 'donor strand complementation': each subunit completes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36778477376f40b02f0a180a893139be
https://doi.org/10.1016/j.jmb.2012.01.020
https://doi.org/10.1016/j.jmb.2012.01.020
Autor:
V. M. Tischenko
Publikováno v:
Molecular Biology. 45:967-975
Isolated constant domains of two Bence Jones proteins, VAD and BIR, are able to form amyloid fibrils, but only the first one retains this feature within the intact protein. The conformation and stability of these proteins were studied using scanning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86c8c666a1217fce76a4ab6b7a2daa71
https://doi.org/10.1134/s002689331105013x
https://doi.org/10.1134/s002689331105013x
Autor:
V. M. Tischenko
Publikováno v:
Biophysics. 56:602-605
It is shown by several methods (circular dichroism, viscometry, intrinsic fluorescence, and fluorescence of labels) that, as in the case of small globular proteins, the folding-unfolding transition in the Caf113–149 subunit under the action of two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b0e3bf7f60a33a7dcabee7efa9b7c94
https://doi.org/10.1134/s0006350911040270
https://doi.org/10.1134/s0006350911040270
Autor:
V M, Tischenko
Publikováno v:
Molekuliarnaia biologiia. 48(3)
Human myeloma immunoglobulin second subclass LOM and SIN, their Fc fragment and firstly obtained hFc fragment in which there is not only low portion of the hinge region, but also its core portion (Cys-Cys-Val-Glu-Cys-Pro-Pro-Cys), have been studied b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0b49bc7561db30a8cb93cee7e6fb2a1
https://pubmed.ncbi.nlm.nih.gov/25831897
https://pubmed.ncbi.nlm.nih.gov/25831897
Autor:
Sheila MacIntyre, Bjørn Olav Brandsdal, Johan Åqvist, Vladimir P. Zav'yalov, Stefan D. Knight, L.J. Fooks, V. M. Tischenko, Anton V. Zavialov
Publikováno v:
Biochemical Journal. 389:685-694
Periplasmic chaperone/usher machineries are used for assembly of filamentous adhesion organelles of Gram-negative pathogens in a process that has been suggested to be driven by folding energy. Structures of mutant chaperone–subunit complexes reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627b357e46023c326efcda66f5216c18
https://doi.org/10.1042/bj20050426
https://doi.org/10.1042/bj20050426
Publikováno v:
Immunology Letters. 90:43-47
Earlier, the electron microscopy and hydrodynamic studies revealed the transformation of the globule-like form of the human (h) IgG3 Kus hinge into a rod-like shape under non-denaturing perturbations [Eur. J. Biochem. 190 (1990) 393]. In this work, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743f272486421ceade7156859d93067a
https://doi.org/10.1016/s0165-2478(03)00161-5
https://doi.org/10.1016/s0165-2478(03)00161-5