Zobrazeno 1 - 10
of 32
pro vyhledávání: '"V M, Rangnekar"'
Autor:
S, Porntadavity, Y, Xu, K, Kiningham, V M, Rangnekar, V, Prachayasittikul, V, Prachayasitikul, D K, St Clair
Publikováno v:
DNA and Cell Biology. 20:473-481
Induction of manganese superoxide dismutase (MnSOD) in response to oxidative stress has been well established in animals, tissues, and cell culture. However, the role of the human MnSOD (hMnSOD) promoter in stimulus-dependent activation of transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0692738a3b346b9f822316a602923bb
https://doi.org/10.1089/104454901316976109
https://doi.org/10.1089/104454901316976109
Autor:
S, Boehrer, K U, Chow, E, Puccetti, M, Ruthardt, S, Godzisard, A, Krapohl, B, Schneider, D, Hoelzer, P S, Mitrou, V M, Rangnekar, E, Weidmann
Publikováno v:
The Hematology Journal. 2:103-107
Prostate apoptosis response gene-4, known as par-4, is a new proapoptotic factor functionally required but not sufficient for apoptosis. Since there is evidence from prostate cancer cells that par-4 is involved in regulation of bcl-2 we assessed expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3febe8c0bb1e328e1ff5898f8ac4b61
https://doi.org/10.1038/sj.thj.6200089
https://doi.org/10.1038/sj.thj.6200089
Autor:
Jonathan D. Licht, Yang Shi, Raymond H. See, V M Rangnekar, Ricky W. Johnstone, S Muthukkumar, Christoph Englert, Stephen P. Sugrue, James C. Wang, Thomas M. Roberts, S F Sells, Daniel A. Haber
Publikováno v:
Molecular and Cellular Biology. 16:6945-6956
The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms' tumor. In this study, we identified par-4 (for prostate apoptosis response) as a WT1-intera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac72e8832917c80a85653b619058ea41
https://doi.org/10.1128/mcb.16.12.6945
https://doi.org/10.1128/mcb.16.12.6945
Publikováno v:
Journal of Biological Chemistry. 267:6240-6248
Human melanoma cells, A375-C6, were "committed" to growth arrest within a few hours of exposure to interleukin-1 (IL-1). Co-treatment with actinomycin D rescued the cells from the "commitment," suggesting that "early" gene activation events may be cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89cc70fecbc571e8592baa1c15cc068c
https://doi.org/10.1016/s0021-9258(18)42687-7
https://doi.org/10.1016/s0021-9258(18)42687-7
Publikováno v:
Journal of Biological Chemistry. 266:2415-2422
Interleukin-1 (IL-1) is an antiproliferative factor for growing human melanoma A375-C6 cells. To define the molecular basis for the action of IL-1, we set out to identify early genes induced by the cytokine in the absence of de novo protein synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce54a8922700ef8beb999d9e024217a5
https://doi.org/10.1016/s0021-9258(18)52260-2
https://doi.org/10.1016/s0021-9258(18)52260-2
Autor:
V M, Rangnekar
Publikováno v:
Apoptosis : an international journal on programmed cell death. 3(2)
The prostate apoptosis response-4 (par-4) gene was isolated in a differential screen for immediate-early genes that are up-regulated during apoptosis of prostate cancer cells. Unlike most other immediate-early genes, par-4 is exclusively induced duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e6cbe74f32bb3d9c1b6d1fb21568bb0
https://pubmed.ncbi.nlm.nih.gov/14646502
https://pubmed.ncbi.nlm.nih.gov/14646502
Publikováno v:
Cancer metastasis reviews. 20(3-4)
Transformation and malignant progression of prostate cancer is regulated by the inability of prostatic epithelial cells to undergo apoptosis rather than by increased cell proliferation. The basic apoptotic machinery of most prostate cancer cells is i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::019f5beb6bcc62431887ae24534ef32c
https://pubmed.ncbi.nlm.nih.gov/12085964
https://pubmed.ncbi.nlm.nih.gov/12085964
Publikováno v:
Cancer research. 61(19)
Prostate cancer cells are generally resistant to apoptosis by conventional therapy. During a search for molecules that may overcome prostate cancer cell survival mechanisms, we identified the prostate apoptosis response-4 (Par-4) gene. Par-4 induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2bafc6a350703a05943d7028758f33f
https://pubmed.ncbi.nlm.nih.gov/11585763
https://pubmed.ncbi.nlm.nih.gov/11585763
Publikováno v:
Cancer gene therapy. 5(1)
Although cloned as an "immediate-early gene," recent studies show that EGR-1 functions in growth regulation and suppression of transformation by transactivation of the transforming growth factor beta-1 (TGF-beta1) gene and cooperation with Sp1, Jun-B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1aa9919798f3aff6354ff4cc726bfd8
https://pubmed.ncbi.nlm.nih.gov/9476963
https://pubmed.ncbi.nlm.nih.gov/9476963
Autor:
E R, Boghaert, S F, Sells, A J, Walid, P, Malone, N M, Williams, M H, Weinstein, R, Strange, V M, Rangnekar
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 8(8)
Prostate apoptosis response 4 (par-4) is a recently identified gene that encodes a transcription factor, Par-4, with a leucine zipper domain. Par-4 protein is constitutively expressed in various cell lines and is functionally required but not suffici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c419d933b4b929aaa9fa433c68ed88cd
https://pubmed.ncbi.nlm.nih.gov/9269897
https://pubmed.ncbi.nlm.nih.gov/9269897