Zobrazeno 1 - 7
of 7
pro vyhledávání: '"V M, Gehle"'
Publikováno v:
Alcoholism, clinical and experimental research. 25(12)
In previous studies, genetic correlations were observed between hypnotic sensitivity to ethanol and high-affinity neurotensin receptor (NTS1) binding. Provisional quantitative trait loci (QTLs) were identified for these traits, and some of these QTLs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec71c33f38d8672611e16ae01f7ba372
https://pubmed.ncbi.nlm.nih.gov/11781501
https://pubmed.ncbi.nlm.nih.gov/11781501
Autor:
V M, Gehle, V G, Erwin
Publikováno v:
Alcoholism, clinical and experimental research. 24(5)
It has been proposed that development of tolerance to the behavioral effects of ethanol depends on the degree of impairment produced by the drug; that is, more sensitive individuals should develop greater tolerance. Tests of this hypothesis with resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6e3fe0efc8a669e826b416426824552
https://pubmed.ncbi.nlm.nih.gov/10832898
https://pubmed.ncbi.nlm.nih.gov/10832898
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 293(1)
Genetic regulation of acute tolerance to ethanol may be associated with ethanol consumption and other ethanol-related behaviors in rodents. We have used lines of mice, selectively bred for high and low acute functional tolerance (HAFT and LAFT, respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::99a9423cc07fdc8a8f872297c7bcc272
https://pubmed.ncbi.nlm.nih.gov/10734169
https://pubmed.ncbi.nlm.nih.gov/10734169
Publikováno v:
Alcoholism, clinical and experimental research. 23(11)
Low doses of the N-methyl-D-aspartate receptor (NMDAR) antagonist MK-801 (dizocilpine) or ethanol increase locomotor activity to a lesser extent in long-sleep (LS), than in short-sleep (SS), mice. LS mice also have fewer brain [3H]MK-801 binding site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d2508b1de90b3faca067f1dc3217bdc6
https://pubmed.ncbi.nlm.nih.gov/10591587
https://pubmed.ncbi.nlm.nih.gov/10591587
Autor:
V M, Gehle, V G, Erwin
Publikováno v:
Alcoholism, clinical and experimental research. 22(2)
The C57BL/6, DBA/2, and recombinant inbred (RI) strains derived from them (BxD RIs) are the most frequently studied mouse strains with regard to genetic regulation of voluntary ethanol consumption (YEC). We have studied VEC in an alternate genetic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::900b7cb4565ac5ff8be1f602a2076a91
https://pubmed.ncbi.nlm.nih.gov/9581646
https://pubmed.ncbi.nlm.nih.gov/9581646
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 280(2)
We have analyzed LSXSS recumbinant inbred for ethanol-induced activity using 2.0 g/kg ethanol and a new method we call ethanol activation slope. The ethanol activation slope provides a robust dose-response measure of ethanol activation, independent o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69f3dc6be4b52f1e02c08ac253436e58
https://pubmed.ncbi.nlm.nih.gov/9023307
https://pubmed.ncbi.nlm.nih.gov/9023307
Autor:
K, Sumikawa, V M, Gehle
Publikováno v:
The Journal of biological chemistry. 267(9)
Each subunit of the nicotinic acetylcholine receptor (AChR) contains two conserved cysteine residues, which are known to form a disulfide bond, in the N-terminal extracellular domain. The role of this retained structural feature in the biogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb2bdf758f88da03fdb0bdc7a8b0443b
https://pubmed.ncbi.nlm.nih.gov/1556136
https://pubmed.ncbi.nlm.nih.gov/1556136