Zobrazeno 1 - 8
of 8
pro vyhledávání: '"V M, Cutuli"'
Publikováno v:
European review for medical and pharmacological sciences. 5(1)
Previous studies indicate that blood levels of cyclosporin-A are increased by concomittant administration of grapefruit juice in healthy subjects and patients. It was suggested that grapefruit juice could inhibit the metabolism of cyclosporin-A by CY
Autor:
G, Clementi, C E, Fiore, N G, Mangano, V M, Cutuli, P, Pennisi, A, Caruso, A, Prato, M, Matera, M, Amico-Roxas
Publikováno v:
Pharmacologytoxicology. 88(1)
Our previous studies show that chronic administration of L-arginine decreases cyclosporin-A-induced bone loss. The present study was designed to investigate whether a soy diet could prevent cyclosporin A-induced osteopenia and eventually improve the
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 50(10)
Two series of novel derivatives based on the thienopyrimidine and pyrimidoindole ring systems, both N-substituted in position 3, have been synthesized. The compounds were obtained by reaction of N-amino groups of 5,6-dimethyl-thieno[2,3-d]pyrimidin-2
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 49(4)
The dialkylamino-alkylation of 3H-pyridazino[4,5-b][1,4]benzothiazin-4(10H)-one-5,5-dioxide 5 produced the 3-dialkylaminoalkyl-derivatives 6. To the same compounds we arrived by selective reduction of the corresponding N-oxides 4, derived from the ox
Publikováno v:
Drugs under experimental and clinical research. 20(1)
Intramuscular administration of medprotine, a protein fraction of human placenta (30-300 kDa), produced dose-dependent and long lasting analgesia as evaluated by various analgesic tests in mice. Activity was found in a dose range of 0.05-0.6 mg/kg in
Publikováno v:
Journal of physiology, Paris. 87(6)
Different classes of GABAergic drugs--baclofen, GABA, muscimol, Na-valproate, Mg-valproate and diazepam--were tested per os on ethanol-induced gastric lesions in rats. The GABAB agonist baclofen failed to affect gastric susceptibility to ethanol dama
Publikováno v:
Drugs under experimental and clinical research. 19(5)
The effects of propionyl-L-carnitine (PLC) in various models of inflammation were studied in rats and mice. PLC (50-200 mg/kg i.p.) dose-dependently inhibited the granuloma pouch induced by croton oil in rats, but failed to inhibit either cotton pell
Publikováno v:
Drugs under experimental and clinical research. 18(11-12)
In this study the pharmacological evaluation of MED-15, a non-acidic prodrug of tolmetin, is described. After oral administration the new compound shows a marked anti-inflammatory activity similar to that of tolmetin, but with minor ulcerogenic actio