Zobrazeno 1 - 10
of 13
pro vyhledávání: '"V L Rothman"'
Autor:
V. L. Rothman, Mark P. Solomon, Mark S. Granick, D. Albo, George P. Tuszynski, Analia Castiglioni, J. P. Arnoletti
Publikováno v:
Cancer. 76:998-1005
Background. Thrombospondin is a high molecular weight adhesive glycoprotein that has been shown to function in mechanisms of tumor progression. The authors' previous studies have shown that thrombospondin promotes human lung carcinoma invasion by up-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74abe215c7e1c72214765ea49e84386c
https://doi.org/10.1002/1097-0142(19950915)76:6<998::aid-cncr2820760613>3.0.co
https://doi.org/10.1002/1097-0142(19950915)76:6<998::aid-cncr2820760613>3.0.co
Publikováno v:
The Journal of Cell Biology
We have previously shown that peptides derived from the thrombospondin sequence, CSVTCG, promoted tumor cell adhesion. To further investigate this observation, the CSVTCG-tumor cell adhesion receptor from A549 human lung adenocarcinoma cells was isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39a024446932bd3201c1c956bb09114
http://europepmc.org/articles/PMC2119506
http://europepmc.org/articles/PMC2119506
Publikováno v:
The Journal of Cell Biology
Thrombospondin (TSP), a major platelet-secreted protein, has recently been shown to have activity in tumor cell metastasis, cell adhesion, and platelet aggregation. The type 1 repeats of TSP contain two copies of CSVTCG and one copy of CSTSCG, per ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a76a41aaf49029e56a62bb0229db7d
https://doi.org/10.1083/jcb.116.1.209
https://doi.org/10.1083/jcb.116.1.209
Publikováno v:
Histology and histopathology. 12(4)
Thrombospondin-1 (TSP-1) is a matrix protein implicated in mechanisms of tumor metastasis. TSP-1 has a characteristic Cysteine-Serine-Valine-Threonine-Cysteine-Glycine (CSVTCG) sequence that functions as a tumor cell adhesion domain. Our laboratory h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a1c4dc9fd5d05718699da6f0927169d
https://pubmed.ncbi.nlm.nih.gov/9302563
https://pubmed.ncbi.nlm.nih.gov/9302563
Autor:
Renato V. Iozzo, Edward A. Fisher, V L Rothman, G P Tuszynski, Ilia Fuki, K M Kuhn, Kevin Jon Williams, I R Lomazov, T L Swenson
Publikováno v:
The Journal of clinical investigation. 100(6)
Cell-surface heparan sulfate proteoglycans have been shown to participate in lipoprotein catabolism, but the roles of specific proteoglycan classes have not been examined previously. Here, we studied the involvement of the syndecan proteoglycan famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2608bef543fc4854cde0676297706871
https://pubmed.ncbi.nlm.nih.gov/9294130
https://pubmed.ncbi.nlm.nih.gov/9294130
Autor:
J P, Arnoletti, D, Albo, M S, Granick, M P, Solomon, A, Castiglioni, V L, Rothman, G P, Tuszynski
Publikováno v:
Cancer. 76(6)
Thrombospondin is a high molecular weight adhesive glycoprotein that has been shown to function in mechanisms of tumor progression. The authors' previous studies have shown that thrombospondin promotes human lung carcinoma invasion by up-regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2e1b9665e76544f4cb2ea682f177ed1a
https://pubmed.ncbi.nlm.nih.gov/8625226
https://pubmed.ncbi.nlm.nih.gov/8625226
Autor:
M.P. Solomon, G.P. Tuszynski, A. Castiglioni, V. L. Rothman, D. Albo, J. P. Arnoletti, M.S. Granick
Publikováno v:
Biochemical and biophysical research communications. 203(2)
A growing body of evidence has recently implicated TSP and TGF-beta in the process of malignancy, such as tumor cell proliferation, tumor angiogenesis, and metastasis. The purpose of the present study was to evaluate potential mechanisms of TSP and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73a092a8d7bde67088fcc1e98acb01a
https://pubmed.ncbi.nlm.nih.gov/8093068
https://pubmed.ncbi.nlm.nih.gov/8093068
Publikováno v:
Oncology research. 5(4-5)
Thrombospondin (TSP) was evaluated for its effect on the capacity of human A549 lung adenocarcinoma cells to invade and degrade fibrin gels. Cells suspended in DMEM containing 0.01 units/mL plasminogen were added to a 2.5 mm diameter well in a 2 mm t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92878ce474ada06252f8a8d972c5a579
https://pubmed.ncbi.nlm.nih.gov/8305744
https://pubmed.ncbi.nlm.nih.gov/8305744
Autor:
G P, Tuszynski, M, Smith, V L, Rothman, D M, Capuzzi, R R, Joseph, J, Katz, E C, Besa, J, Treat, H I, Switalska
Publikováno v:
Thrombosis and haemostasis. 67(6)
Thrombospondin (TSP), a large glycoprotein present in platelets, and various normal and tumor tissues, has recently been shown to promote cell adhesion and platelet aggregation. Most importantly because TSP has been shown to promote metastasis of mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28533189a151b38d16cb9e4d3e9ec95b
https://pubmed.ncbi.nlm.nih.gov/1509400
https://pubmed.ncbi.nlm.nih.gov/1509400
Publikováno v:
Blood. 72:109-115
Thrombospondin (TSP), isolated from human platelets, promotes aggregation of both nonstimulated platelets and platelets stimulated with thrombin or ADP. The TSP-promoted aggregation is specific since a monoclonal antibody against TSP inhibits the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6ab1aef2566d27f47c53d01380157b
https://doi.org/10.1182/blood.v72.1.109.109
https://doi.org/10.1182/blood.v72.1.109.109