Zobrazeno 1 - 8
of 8
pro vyhledávání: '"V L, Tybulewicz"'
Publikováno v:
Blood. 96(7)
The tyrosine kinase Syk has been proposed to play a critical role in the antiapoptotic effect of interleukin (IL)-5 in human eosinophils. However, little is known about the involvement of Syk in other IL-5-mediated activation events. To further addre
Autor:
F, Colucci, D, Guy-Grand, A, Wilson, M, Turner, E, Schweighoffer, V L, Tybulewicz, J P, Di Santo
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 164(10)
The Syk protein tyrosine kinase (PTK) is essential for B, but not T or NK, cell development, although certain T cell subsets (i.e., gamma delta T cells of intestine and skin) appear to be dependent on Syk. In this report, we have re-evaluated the rol
Publikováno v:
European journal of immunology. 29(9)
The T cell repertoire is shaped by positive and negative selection of thymocytes. TCR-mediated signals that determine these selection processes are only partly understood. The CD45 tyrosine phosphatase has been shown to be important for signal transd
Publikováno v:
European journal of immunology. 29(2)
Vav, a guanine nucleotide exchange factor for members of the Rho family of small GTPases, is activated through engagement of B and T lymphocyte antigen receptors. It is important for establishing the signaling threshold of the TCR, as mice lacking Va
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(4)
Fc gamma RIIB are low-affinity receptors for IgG whose intracytoplasmic domain contains an immunoreceptor tyrosine-based inhibition motif (ITIM). Fc gamma RIIB inhibit cell activation triggered by receptors that signal via immunoreceptor tyrosine-bas
Publikováno v:
Blood. 88(7)
Interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5 are major hematopoietic cytokines produced by activated T cells and exhibit similar biologic activities by signaling through a common receptor subunit (beta c).
Publikováno v:
The Biochemical journal. 234(1)
The transposon Tn7 is unusual as it transposes at high frequencies from episomal elements to a unique site in the Escherichia coli chromosome. This unique site is within a region of dyad symmetry that we have demonstrated to be the transcriptional te
Publikováno v:
Journal of molecular biology. 179(2)
The nucleotide sequence has been determined of a 12,368 base-pair region of DNA cloned from the non-sulphur photosynthetic bacterium Rhodopseudomonas blastica. It contains a cluster of six genes of which five encode the subunits of F1-ATPase; the six