Zobrazeno 1 - 10
of 17
pro vyhledávání: '"V L, Hopwood"'
Publikováno v:
International journal of oncology. 7(4)
The development of human cancer is generally considered to be the result of genetic mutations that cause a progressively more malignant phenotype. We propose that such genetic changes can be observed in a small number of lymphocytic metaphase plates.
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 7(4)
The purpose of this study was to measure DNA repair capacity and mutagen sensitivity in patients who have had three or more primary forms of cancer. It was hypothesized that, if abnormalities in DNA repair and mutagen sensitivity were cancer suscepti
Publikováno v:
Annals of clinical and laboratory science. 28(1)
Chronic lymphocytic leukemia (CLL) is most characteristically associated with the cytogenetic abnormalities +12, 13q14, and 14q32. Recently abnormalities of chromosome 6 have been reported in patients with mantle zone lymphoma, CLL mixed type, and a
Publikováno v:
Anticancer research. 16(6B)
We have modified and shortened the routine fluorescence in situ hybridization (FISH) technique by using microwave or formalin pretreatment for artificially aging and microwave heating only for dehydrating the regular chromosome preparations. The all-
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 4(7)
Chromosomal anomalies were analyzed in the lymphocyte cultures among 96 untreated lung cancer patients and 74 clinically normal comparison subjects. The analysis revealed that15% of the lung cancer patients showed structural or numerical rearrangemen
Autor:
S, Gagos, V L, Hopwood, D, Iliopoulos, A, Kostakis, P, Karayannakos, H, Yatzides, G D, Skalkeas, S, Pathak
Publikováno v:
Anticancer research. 15(2)
The purpose of this study was to identify specific chromosomal abnormalities that might be involved in colon cancer metastasis. For this reason, we performed extensive karyotypic analysis on two colon cancer cell lines (SW480 and SW620) established f
Autor:
V L, Hopwood, S, Pathak
Publikováno v:
American biotechnology laboratory. 12(11)
Publikováno v:
International Journal of Oncology.
To ascertain whether the bcl-2 oncogene plays a role in the initial stages of skin carcinogenesis by preventing differentiation of epidermal keratinocytes, we transfected primary human keratinocytes with the human bcl-2 gene and then determined wheth
Autor:
G N, Thalmann, P E, Anezinis, S M, Chang, H E, Zhau, E E, Kim, V L, Hopwood, S, Pathak, A C, von Eschenbach, L W, Chung
Publikováno v:
Cancer research. 54(10)
Our laboratory has previously reported on the derivation of LNCaP cell sublines from LNCaP tumors maintained in castrated and intact athymic male mice. These LNCaP sublines differ from the parental line in tumorigenicity and androgen dependence. This
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 2(6)
We studied chromosomal alterations in the peripheral blood lymphocytes of 10 individuals with colorectal polyps and 10 asymptomatic first-degree relatives of patients with colon cancer or colorectal polyps. The analysis was performed on T-lymphocytes