Zobrazeno 1 - 10
of 65
pro vyhledávání: '"V L, Andronova"'
Autor:
V. L. Andronova, G. A. Galegov, V. V. Musiyak, O. A. Vozdvizhenskaya, G. L. Levit, V. P. Krasnov
Publikováno v:
Вопросы вирусологии, Vol 65, Iss 6, Pp 373-380 (2021)
Introduction. Herpes simplex viruses type 1 (HSV-1) are extremely widespread throughout the world and, similar to other herpesviruses, establish lifelong persistent infection in the host. Reactivating sporadically, HSV-1 elicits recurrences in both i
Externí odkaz:
https://doaj.org/article/f68105461a154e859169cdde219cf587
Autor:
G. A. Galegov, V. L. Andronova
Publikováno v:
Вопросы вирусологии, Vol 64, Iss 1, Pp 12-15 (2019)
The new domestic antiretroviral drug 6HP, which is ammonium-3’-azido-3’-deoxythymidine-5’-carbomoylphosphonate, shows a high level of anti-HIV activity in cultures of lymphoblastoid cells. In a organism, the 6HP is converted to azidothymidine,
Externí odkaz:
https://doaj.org/article/15b2afc7317d44eaa3c2ab681963e43f
Autor:
V. L. Andronova
Publikováno v:
Вопросы вирусологии, Vol 63, Iss 6, Pp 250-260 (2018)
A number of synthetic compounds, such as the nucleoside analog ganciclovir, its L-valine ester (a metabolic precursor of ganciclovir) and pyrophosphate analog foscarnet, are permitted for the treatment of HCMV-related diseases in the WHO European Reg
Externí odkaz:
https://doaj.org/article/8ee069e58d204d94925bf5b65f9de228
Autor:
V. L. Andronova
Publikováno v:
Вопросы вирусологии, Vol 63, Iss 5, Pp 202-211 (2018)
Modern chemotherapy of cytomegalovirus (CMV) infections has a very limited arsenal of first-line drugs. These are preparations of ganciclovir (GCV) belonging to the class of modified nucleosides and its metabolic precursor ganciclovir valine ester. A
Externí odkaz:
https://doaj.org/article/98588fe3e7b44c3e927576d6bf31b4fc
Autor:
D. G. Maldov, V. L. Andronova, S. S. Grigorian, E. I. Isaeva, A. A. Balakina, A. A. Terentyev, A. V. Ilyichev, G. A. Galegov
Publikováno v:
Вопросы вирусологии, Vol 63, Iss 5, Pp 218-223 (2018)
Increased protease activity and a significant amount of granzyme B were observed in in organs of mice infected with acute herpes simplex virus HSV-1 with the introduction of Stimforte (100 or 250 µg/mouse). Thus, this drug activates killer cells, wh
Externí odkaz:
https://doaj.org/article/9137d308374745df946c1e5d4a91dde1
Autor:
D. A. Gruzdev, A. A. Telegina, V. A. Ol’shevskaya, V. L. Andronova, G. A. Galegov, V. V. Zarubaev, G. L. Levit, V. P. Krasnov
Publikováno v:
Russian Chemical Bulletin. 71:2375-2382
Autor:
V. L. Andronova
Publikováno v:
Вопросы вирусологии, Vol 63, Iss 4, Pp 149-159 (2018)
A key role in the treatment of herpesviral infections is played by modified nucleosides and their predecessors - acyclovir, its L-valine ester (valaciclovir) and famciclovir (prodrug of penciclovir). The biological activity of compounds of this class
Externí odkaz:
https://doaj.org/article/2ad8573b629a4838a444d751f2e98da6
Publikováno v:
Вопросы вирусологии, Vol 62, Iss 5, Pp 211-218 (2017)
The combined action of the immunostimulatory drug Stimforte and the basic etiotropic drug acyclovir commonly used to treat herpes infections was studied using the model of lethal experimental infection of mice BALB/c with herpes simplex virus type 1.
Externí odkaz:
https://doaj.org/article/8f4daad6d8ee420eba980e52a8d50ed4
Publikováno v:
Acta Naturae. 14:16-38
1,4-Pyrazine-3-carboxamide-based antiviral compounds have been under intensive study for the last 20 years. One of these compounds, favipiravir (6-fluoro-3-hydroxypyrazine-2-carboxamide, T-705), is approved for use against the influenza infection in
Publikováno v:
Вопросы вирусологии, Vol 61, Iss 4, Pp 172-175 (2016)
In the study of the immunostimulation preparation Stimforte activity using the model of the experimental herpes virus infection BALB/c, mice has shown that sera from mice treated with the drug on the 4th and 7th day after infection possessed a 3 time
Externí odkaz:
https://doaj.org/article/0698c0f1ff3d478485e4075a55d47b36