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pro vyhledávání: '"V K, Ramiya"'
Publikováno v:
Revue Scientifique et Technique de l'OIE. 17:108-120
Studies of the major histocompatibility complex (MHC) of cattle over the past twenty years have revealed a reasonably detailed picture of the genetic organisation and function of the genes within this genetic system. Serological and biochemical analy
Publikováno v:
Pediatric diabetes. 2(4)
Type 1 (insulin-dependent) diabetes is one of the most costly chronic diseases of children and adolescents in North America and Europe. It occurs in genetically predisposed individuals when the immune system attacks and destroys specifically the insu
Autor:
N K Maclaren, V K Ramiya
Publikováno v:
Hormone research. 48
Insulin-dependent diabetes (IDD) is a chronic immune-endocrine disease in which there is a progressive destruction of insulin-secreting pancreatic beta cells, caused primarily by autoreactive T cells. Many islet cell proteins including insulin, gluta
Autor:
M S, Hanson, M, Cetkovic-Cvrlje, V K, Ramiya, M A, Atkinson, N K, Maclaren, B, Singh, J F, Elliott, D V, Serreze, E H, Leiter
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 157(3)
Two homozygous lines of transgenic NOD/Lt mice expressing MHC class II I-E molecules at quantitatively different levels were utilized to study mechanisms of I-E-mediated diabetes prevention. In line 12, I-E expression on APC at levels comparable with